Yang Zhao

Xiaofan Li, Chenming Wu, Zhao Yang et al.

This paper presents DriVerse, a generative model for simulating navigation-driven driving scenes from a single image and a future trajectory. Previous autonomous driving world models either directly feed the trajectory or discrete control signals into the generation pipeline, leading to poor alignment between the control inputs and the implicit features of the 2D base generative model, which results in low-fidelity video outputs. Some methods use coarse textual commands or discrete vehicle control signals, which lack the precision to guide fine-grained, trajectory-specific video generation, making them unsuitable for evaluating actual autonomous driving algorithms. DriVerse introduces explicit trajectory guidance in two complementary forms: it tokenizes trajectories into textual prompts using a predefined trend vocabulary for seamless language integration, and converts 3D trajectories into 2D spatial motion priors to enhance control over static content within the driving scene. To better handle dynamic objects, we further introduce a lightweight motion alignment module, which focuses on the inter-frame consistency of dynamic pixels, significantly enhancing the temporal coherence of moving elements over long sequences. With minimal training and no need for additional data, DriVerse outperforms specialized models on future video generation tasks across both the nuScenes and Waymo datasets. The code and models will be released to the public.

Xiuyuan Hu, Guoqing Liu, Yang Zhao et al. · tsinghua

De novo drug design is a pivotal issue in pharmacology and a new area of focus in AI for science research. A central challenge in this field is to generate molecules with specific properties while also producing a wide range of diverse candidates. Although advanced technologies such as transformer models and reinforcement learning have been applied in drug design, their potential has not been fully realized. Therefore, we propose MolRL-MGPT, a reinforcement learning algorithm with multiple GPT agents for drug molecular generation. To promote molecular diversity, we encourage the agents to collaborate in searching for desirable molecules in diverse directions. Our algorithm has shown promising results on the GuacaMol benchmark and exhibits efficacy in designing inhibitors against SARS-CoV-2 protein targets. The codes are available at: https://github.com/HXYfighter/MolRL-MGPT.

Xiaowei Yuan, Zhao Yang, Yequan Wang et al.

In the Retrieval-Augmented Generation (RAG) system, advanced Large Language Models (LLMs) have emerged as effective Query Likelihood Models (QLMs) in an unsupervised way, which re-rank documents based on the probability of generating the query given the content of a document. However, directly prompting LLMs to approximate QLMs inherently is biased, where the estimated distribution might diverge from the actual document-specific distribution. In this study, we introduce a novel framework, $\mathrm{UR^3}$, which leverages Bayesian decision theory to both quantify and mitigate this estimation bias. Specifically, $\mathrm{UR^3}$ reformulates the problem as maximizing the probability of document generation, thereby harmonizing the optimization of query and document generation probabilities under a unified risk minimization objective. Our empirical results indicate that $\mathrm{UR^3}$ significantly enhances re-ranking, particularly in improving the Top-1 accuracy. It benefits the QA tasks by achieving higher accuracy with fewer input documents.