Shipeng Wang

Zheni Zeng, Bangchen Yin, Shipeng Wang et al.

Natural language is expected to be a key medium for various human-machine interactions in the era of large language models. When it comes to the biochemistry field, a series of tasks around molecules (e.g., property prediction, molecule mining, etc.) are of great significance while having a high technical threshold. Bridging the molecule expressions in natural language and chemical language can not only hugely improve the interpretability and reduce the operation difficulty of these tasks, but also fuse the chemical knowledge scattered in complementary materials for a deeper comprehension of molecules. Based on these benefits, we propose the conversational molecular design, a novel task adopting natural language for describing and editing target molecules. To better accomplish this task, we design ChatMol, a knowledgeable and versatile generative pre-trained model, enhanced by injecting experimental property information, molecular spatial knowledge, and the associations between natural and chemical languages into it. Several typical solutions including large language models (e.g., ChatGPT) are evaluated, proving the challenge of conversational molecular design and the effectiveness of our knowledge enhancement method. Case observations and analysis are conducted to provide directions for further exploration of natural-language interaction in molecular discovery.

Shipeng Wang, Qingzhong Li, Lizhen Cui et al.

Crowdsourcing, in which human intelligence and productivity is dynamically mobilized to tackle tasks too complex for automation alone to handle, has grown to be an important research topic and inspired new businesses (e.g., Uber, Airbnb). Over the years, crowdsourcing has morphed from providing a platform where workers and tasks can be matched up manually into one which leverages data-driven algorithmic management approaches powered by artificial intelligence (AI) to achieve increasingly sophisticated optimization objectives. In this paper, we provide a survey presenting a unique systematic overview on how AI can empower crowdsourcing to improve its efficiency - which we refer to as AI-Empowered Crowdsourcing(AIEC). We propose a taxonomy which divides AIEC into three major areas: 1) task delegation, 2) motivating workers, and 3) quality control, focusing on the major objectives which need to be accomplished. We discuss the limitations and insights, and curate the challenges of doing research in each of these areas to highlight promising future research directions.