Accurate Leukocyte Detection Based on Deformable-DETR and Multi-Level Feature Fusion for Aiding Diagnosis of Blood DiseasesYifei Chen, Chenyan Zhang, Ben Chen et al.
In standard hospital blood tests, the traditional process requires doctors to manually isolate leukocytes from microscopic images of patients' blood using microscopes. These isolated leukocytes are then categorized via automatic leukocyte classifiers to determine the proportion and volume of different types of leukocytes present in the blood samples, aiding disease diagnosis. This methodology is not only time-consuming and labor-intensive, but it also has a high propensity for errors due to factors such as image quality and environmental conditions, which could potentially lead to incorrect subsequent classifications and misdiagnosis. To address these issues, this paper proposes an innovative method of leukocyte detection: the Multi-level Feature Fusion and Deformable Self-attention DETR (MFDS-DETR). To tackle the issue of leukocyte scale disparity, we designed the High-level Screening-feature Fusion Pyramid (HS-FPN), enabling multi-level fusion. This model uses high-level features as weights to filter low-level feature information via a channel attention module and then merges the screened information with the high-level features, thus enhancing the model's feature expression capability. Further, we address the issue of leukocyte feature scarcity by incorporating a multi-scale deformable self-attention module in the encoder and using the self-attention and cross-deformable attention mechanisms in the decoder, which aids in the extraction of the global features of the leukocyte feature maps. The effectiveness, superiority, and generalizability of the proposed MFDS-DETR method are confirmed through comparisons with other cutting-edge leukocyte detection models using the private WBCDD, public LISC and BCCD datasets. Our source code and private WBCCD dataset are available at https://github.com/JustlfC03/MFDS-DETR.
24.3AIDec 3, 2025
MemVerse: Multimodal Memory for Lifelong Learning AgentsJunming Liu, Yifei Sun, Weihua Cheng et al.
Despite rapid progress in large-scale language and vision models, AI agents still suffer from a fundamental limitation: they cannot remember. Without reliable memory, agents catastrophically forget past experiences, struggle with long-horizon reasoning, and fail to operate coherently in multimodal or interactive environments. We introduce MemVerse, a model-agnostic, plug-and-play memory framework that bridges fast parametric recall with hierarchical retrieval-based memory, enabling scalable and adaptive multimodal intelligence. MemVerse maintains short-term memory for recent context while transforming raw multimodal experiences into structured long-term memories organized as hierarchical knowledge graphs. This design supports continual consolidation, adaptive forgetting, and bounded memory growth. To handle real-time demands, MemVerse introduces a periodic distillation mechanism that compresses essential knowledge from long-term memory into the parametric model, allowing fast, differentiable recall while preserving interpretability. Extensive experiments demonstrate that MemVerse significantly improves multimodal reasoning and continual learning efficiency, empowering agents to remember, adapt, and reason coherently across extended interactions.
8.3CLNov 30, 2025
Table as a Modality for Large Language ModelsLiyao Li, Chao Ye, Wentao Ye et al.
To migrate the remarkable successes of Large Language Models (LLMs), the community has made numerous efforts to generalize them to the table reasoning tasks for the widely deployed tabular data. Despite that, in this work, by showing a probing experiment on our proposed StructQA benchmark, we postulate that even the most advanced LLMs (such as GPTs) may still fall short of coping with tabular data. More specifically, the current scheme often simply relies on serializing the tabular data, together with the meta information, then inputting them through the LLMs. We argue that the loss of structural information is the root of this shortcoming. In this work, we further propose TAMO, which bears an ideology to treat the tables as an independent modality integrated with the text tokens. The resulting model in TAMO is a multimodal framework consisting of a hypergraph neural network as the global table encoder seamlessly integrated with the mainstream LLM. Empirical results on various benchmarking datasets, including HiTab, WikiTQ, WikiSQL, FeTaQA, and StructQA, have demonstrated significant improvements on generalization with an average relative gain of 42.65%.
6.2CVNov 12, 2025
WDT-MD: Wavelet Diffusion Transformers for Microaneurysm Detection in Fundus ImagesYifei Sun, Yuzhi He, Junhao Jia et al.
Microaneurysms (MAs), the earliest pathognomonic signs of Diabetic Retinopathy (DR), present as sub-60 $μm$ lesions in fundus images with highly variable photometric and morphological characteristics, rendering manual screening not only labor-intensive but inherently error-prone. While diffusion-based anomaly detection has emerged as a promising approach for automated MA screening, its clinical application is hindered by three fundamental limitations. First, these models often fall prey to "identity mapping", where they inadvertently replicate the input image. Second, they struggle to distinguish MAs from other anomalies, leading to high false positives. Third, their suboptimal reconstruction of normal features hampers overall performance. To address these challenges, we propose a Wavelet Diffusion Transformer framework for MA Detection (WDT-MD), which features three key innovations: a noise-encoded image conditioning mechanism to avoid "identity mapping" by perturbing image conditions during training; pseudo-normal pattern synthesis via inpainting to introduce pixel-level supervision, enabling discrimination between MAs and other anomalies; and a wavelet diffusion Transformer architecture that combines the global modeling capability of diffusion Transformers with multi-scale wavelet analysis to enhance reconstruction of normal retinal features. Comprehensive experiments on the IDRiD and e-ophtha MA datasets demonstrate that WDT-MD outperforms state-of-the-art methods in both pixel-level and image-level MA detection. This advancement holds significant promise for improving early DR screening.
3.3ITNov 5, 2024
Receiver-Centric Generative Semantic CommunicationsXunze Liu, Yifei Sun, Zhaorui Wang et al.
This paper investigates semantic communications between a transmitter and a receiver, where original data, such as videos of interest to the receiver, is stored at the transmitter. Although significant process has been made in semantic communications, a fundamental design problem is that the semantic information is extracted based on certain criteria at the transmitter alone, without considering the receiver's specific information needs. As a result, critical information of primary concern to the receiver may be lost. In such cases, the semantic transmission becomes meaningless to the receiver, as all received information is irrelevant to its interests. To solve this problem, this paper presents a receiver-centric generative semantic communication system, where each transmission is initialized by the receiver. Specifically, the receiver first sends its request for the desired semantic information to the transmitter at the start of each transmission. Then, the transmitter extracts the required semantic information accordingly. A key challenge is how the transmitter understands the receiver's requests for semantic information and extracts the required semantic information in a reasonable and robust manner. We address this challenge by designing a well-structured framework and leveraging off-the-shelf generative AI products, such as GPT-4, along with several specialized tools for detection and estimation. Evaluation results demonstrate the feasibility and effectiveness of the proposed new semantic communication system.
3.6CVNov 21, 2025
ReBrain: Brain MRI Reconstruction from Sparse CT Slice via Retrieval-Augmented DiffusionJunming Liu, Yifei Sun, Weihua Cheng et al.
Magnetic Resonance Imaging (MRI) plays a crucial role in brain disease diagnosis, but it is not always feasible for certain patients due to physical or clinical constraints. Recent studies attempt to synthesize MRI from Computed Tomography (CT) scans; however, low-dose protocols often result in highly sparse CT volumes with poor through-plane resolution, making accurate reconstruction of the full brain MRI volume particularly challenging. To address this, we propose ReBrain, a retrieval-augmented diffusion framework for brain MRI reconstruction. Given any 3D CT scan with limited slices, we first employ a Brownian Bridge Diffusion Model (BBDM) to synthesize MRI slices along the 2D dimension. Simultaneously, we retrieve structurally and pathologically similar CT slices from a comprehensive prior database via a fine-tuned retrieval model. These retrieved slices are used as references, incorporated through a ControlNet branch to guide the generation of intermediate MRI slices and ensure structural continuity. We further account for rare retrieval failures when the database lacks suitable references and apply spherical linear interpolation to provide supplementary guidance. Extensive experiments on SynthRAD2023 and BraTS demonstrate that ReBrain achieves state-of-the-art performance in cross-modal reconstruction under sparse conditions.
4.1LGOct 21, 2025
Towards Universal Solvers: Using PGD Attack in Active Learning to Increase Generalizability of Neural Operators as Knowledge Distillation from Numerical PDE SolversYifei Sun
Nonlinear PDE solvers require fine space-time discretizations and local linearizations, leading to high memory cost and slow runtimes. Neural operators such as FNOs and DeepONets offer fast single-shot inference by learning function-to-function mappings and truncating high-frequency components, but they suffer from poor out-of-distribution (OOD) generalization, often failing on inputs outside the training distribution. We propose an adversarial teacher-student distillation framework in which a differentiable numerical solver supervises a compact neural operator while a PGD-style active sampling loop searches for worst-case inputs under smoothness and energy constraints to expand the training set. Using differentiable spectral solvers enables gradient-based adversarial search and stabilizes sample mining. Experiments on Burgers and Navier-Stokes systems demonstrate that adversarial distillation substantially improves OOD robustness while preserving the low parameter cost and fast inference of neural operators.
1.5NEOct 24, 2017
Simplex Search Based Brain Storm OptimizationWei Chen, YingYing Cao, Shi Cheng et al.
Through modeling human's brainstorming process, the brain storm optimization (BSO) algorithm has become a promising population-based evolutionary algorithm. However, BSO is pointed out that it possesses a degenerated L-curve phenomenon, i.e., it often gets near optimum quickly but needs much more cost to improve the accuracy. To overcome this question in this paper, an excellent direct search based local solver, the Nelder-Mead Simplex (NMS) method is adopted in BSO. Through combining BSO's exploration ability and NMS's exploitation ability together, a simplex search based BSO (Simplex-BSO) is developed via a better balance between global exploration and local exploitation. Simplex-BSO is shown to be able to eliminate the degenerated L-curve phenomenon on unimodal functions, and alleviate significantly this phenomenon on multimodal functions. Large number of experimental results show that Simplex-BSO is a promising algorithm for global optimization problems.