Jing Cui

Yu Cai, Cheng Jin, Jiabo Ma et al.

Pathology foundation models (PFMs) have enabled robust generalization in computational pathology through large-scale datasets and expansive architectures, but their substantial computational cost, particularly for gigapixel whole slide images, limits clinical accessibility and scalability. Here, we present LitePath, a deployment-friendly foundational framework designed to mitigate model over-parameterization and patch level redundancy. LitePath integrates LiteFM, a compact model distilled from three large PFMs (Virchow2, H-Optimus-1 and UNI2) using 190 million patches, and the Adaptive Patch Selector (APS), a lightweight component for task-specific patch selection. The framework reduces model parameters by 28x and lowers FLOPs by 403.5x relative to Virchow2, enabling deployment on low-power edge hardware such as the NVIDIA Jetson Orin Nano Super. On this device, LitePath processes 208 slides per hour, 104.5x faster than Virchow2, and consumes 0.36 kWh per 3,000 slides, 171x lower than Virchow2 on an RTX3090 GPU. We validated accuracy using 37 cohorts across four organs and 26 tasks (26 internal, 9 external, and 2 prospective), comprising 15,672 slides from 9,808 patients disjoint from the pretraining data. LitePath ranks second among 19 evaluated models and outperforms larger models including H-Optimus-1, mSTAR, UNI2 and GPFM, while retaining 99.71% of the AUC of Virchow2 on average. To quantify the balance between accuracy and efficiency, we propose the Deployability Score (D-Score), defined as the weighted geometric mean of normalized AUC and normalized FLOP, where LitePath achieves the highest value, surpassing Virchow2 by 10.64%. These results demonstrate that LitePath enables rapid, cost-effective and energy-efficient pathology image analysis on accessible hardware while maintaining accuracy comparable to state-of-the-art PFMs and reducing the carbon footprint of AI deployment.

Miao Ye, Suxiao Wang, Jiaguang Han et al.

Detecting anomalies in the data collected by WSNs can provide crucial evidence for assessing the reliability and stability of WSNs. Existing methods for WSN anomaly detection often face challenges such as the limited extraction of spatiotemporal correlation features, the absence of sample labels, few anomaly samples, and an imbalanced sample distribution. To address these issues, a spatiotemporal correlation detection model (MTAD-RD) considering both model architecture and a two-stage training strategy perspective is proposed. In terms of model structure design, the proposed MTAD-RD backbone network includes a retentive network (RetNet) enhanced by a cross-retention (CR) module, a multigranular feature fusion module, and a graph attention network module to extract internode correlation information. This proposed model can integrate the intermodal correlation features and spatial features of WSN neighbor nodes while extracting global information from time series data. Moreover, its serialized inference characteristic can remarkably reduce inference overhead. For model training, a two-stage training approach was designed. First, a contrastive learning proxy task was designed for time series data with graph structure information in WSNs, enabling the backbone network to learn transferable features from unlabeled data using unsupervised contrastive learning methods, thereby addressing the issue of missing sample labels in the dataset. Then, a caching-based sample sampler was designed to divide samples into few-shot and contrastive learning data. A specific joint loss function was developed to jointly train the dual-graph discriminator network to address the problem of sample imbalance effectively. In experiments carried out on real public datasets, the designed MTAD-RD anomaly detection method achieved an F1 score of 90.97%, outperforming existing supervised WSN anomaly detection methods.