Yan Wang

Guanghui Fu, Qing Zhao, Jianqiang Li et al.

In the contemporary landscape of social media, an alarming number of users express negative emotions, some of which manifest as strong suicidal intentions. This situation underscores a profound need for trained psychological counselors who can enact effective mental interventions. However, the development of these professionals is often an imperative but time-consuming task. Consequently, the mobilization of non-professionals or volunteers in this capacity emerges as a pressing concern. Leveraging the capabilities of artificial intelligence, and in particular, the recent advances in large language models, offers a viable solution to this challenge. This paper introduces a novel model constructed on the foundation of large language models to fully assist non-professionals in providing psychological interventions on online user discourses. This framework makes it plausible to harness the power of non-professional counselors in a meaningful way. A comprehensive study was conducted involving ten professional psychological counselors of varying expertise, evaluating the system across five critical dimensions. The findings affirm that our system is capable of analyzing patients' issues with relative accuracy and proffering professional-level strategies recommendations, thereby enhancing support for non-professionals. This research serves as a compelling validation of the application of large language models in the field of psychology and lays the groundwork for a new paradigm of community-based mental health support.

Ruochi Zhang, Haoran Wu, Yuting Xiu et al.

In recent years, the scientific community has become increasingly interested on peptides with non-canonical amino acids due to their superior stability and resistance to proteolytic degradation. These peptides present promising modifications to biological, pharmacological, and physiochemical attributes in both endogenous and engineered peptides. Notwithstanding their considerable advantages, the scientific community exhibits a conspicuous absence of an effective pre-trained model adept at distilling feature representations from such complex peptide sequences. We herein propose PepLand, a novel pre-training architecture for representation and property analysis of peptides spanning both canonical and non-canonical amino acids. In essence, PepLand leverages a comprehensive multi-view heterogeneous graph neural network tailored to unveil the subtle structural representations of peptides. Empirical validations underscore PepLand's effectiveness across an array of peptide property predictions, encompassing protein-protein interactions, permeability, solubility, and synthesizability. The rigorous evaluation confirms PepLand's unparalleled capability in capturing salient synthetic peptide features, thereby laying a robust foundation for transformative advances in peptide-centric research domains. We have made all the source code utilized in this study publicly accessible via GitHub at https://github.com/zhangruochi/pepland

Zhiheng Cheng, Qingyue Wei, Hongru Zhu et al.

The Segment Anything Model (SAM) has garnered significant attention for its versatile segmentation abilities and intuitive prompt-based interface. However, its application in medical imaging presents challenges, requiring either substantial training costs and extensive medical datasets for full model fine-tuning or high-quality prompts for optimal performance. This paper introduces H-SAM: a prompt-free adaptation of SAM tailored for efficient fine-tuning of medical images via a two-stage hierarchical decoding procedure. In the initial stage, H-SAM employs SAM's original decoder to generate a prior probabilistic mask, guiding a more intricate decoding process in the second stage. Specifically, we propose two key designs: 1) A class-balanced, mask-guided self-attention mechanism addressing the unbalanced label distribution, enhancing image embedding; 2) A learnable mask cross-attention mechanism spatially modulating the interplay among different image regions based on the prior mask. Moreover, the inclusion of a hierarchical pixel decoder in H-SAM enhances its proficiency in capturing fine-grained and localized details. This approach enables SAM to effectively integrate learned medical priors, facilitating enhanced adaptation for medical image segmentation with limited samples. Our H-SAM demonstrates a 4.78% improvement in average Dice compared to existing prompt-free SAM variants for multi-organ segmentation using only 10% of 2D slices. Notably, without using any unlabeled data, H-SAM even outperforms state-of-the-art semi-supervised models relying on extensive unlabeled training data across various medical datasets. Our code is available at https://github.com/Cccccczh404/H-SAM.

Xinjie Zhang, Ren Yang, Dailan He et al.

Implicit neural representations (INRs) have emerged as a promising approach for video storage and processing, showing remarkable versatility across various video tasks. However, existing methods often fail to fully leverage their representation capabilities, primarily due to inadequate alignment of intermediate features during target frame decoding. This paper introduces a universal boosting framework for current implicit video representation approaches. Specifically, we utilize a conditional decoder with a temporal-aware affine transform module, which uses the frame index as a prior condition to effectively align intermediate features with target frames. Besides, we introduce a sinusoidal NeRV-like block to generate diverse intermediate features and achieve a more balanced parameter distribution, thereby enhancing the model's capacity. With a high-frequency information-preserving reconstruction loss, our approach successfully boosts multiple baseline INRs in the reconstruction quality and convergence speed for video regression, and exhibits superior inpainting and interpolation results. Further, we integrate a consistent entropy minimization technique and develop video codecs based on these boosted INRs. Experiments on the UVG dataset confirm that our enhanced codecs significantly outperform baseline INRs and offer competitive rate-distortion performance compared to traditional and learning-based codecs. Code is available at https://github.com/Xinjie-Q/Boosting-NeRV.

Zhongjiang He, Zihan Wang, Xinzhang Liu et al.

In this technical report, we present TeleChat, a collection of large language models (LLMs) with parameters of 3 billion, 7 billion and 12 billion. It includes pretrained language models as well as fine-tuned chat models that is aligned with human preferences. TeleChat is initially pretrained on an extensive corpus containing a diverse collection of texts from both English and Chinese languages, including trillions of tokens. Subsequently, the model undergoes fine-tuning to align with human preferences, following a detailed methodology that we describe. We evaluate the performance of TeleChat on various tasks, including language understanding, mathematics, reasoning, code generation, and knowledge-based question answering. Our findings indicate that TeleChat achieves comparable performance to other open-source models of similar size across a wide range of public benchmarks. To support future research and applications utilizing LLMs, we release the fine-tuned model checkpoints of TeleChat's 7B and 12B variant, along with code and a portion of our pretraining data, to the public community.

Xingtong Ge, Xin Zhang, Tongda Xu et al.

The Distribution Matching Distillation (DMD) has been successfully applied to text-to-image diffusion models such as Stable Diffusion (SD) 1.5. However, vanilla DMD suffers from convergence difficulties on large-scale flow-based text-to-image models, such as SD 3.5 and FLUX. In this paper, we first analyze the issues when applying vanilla DMD on large-scale models. Then, to overcome the scalability challenge, we propose implicit distribution alignment (IDA) to regularize the distance between the generator and fake distribution. Furthermore, we propose intra-segment guidance (ISG) to relocate the timestep importance distribution from the teacher model. With IDA alone, DMD converges for SD 3.5; employing both IDA and ISG, DMD converges for SD 3.5 and FLUX.1 dev. Along with other improvements such as scaled up discriminator models, our final model, dubbed \textbf{SenseFlow}, achieves superior performance in distillation for both diffusion based text-to-image models such as SDXL, and flow-matching models such as SD 3.5 Large and FLUX. The source code will be avaliable at https://github.com/XingtongGe/SenseFlow.

Rongwei Xu, Guanfeng Liu, Yan Wang et al.

Trust plays an essential role in an individual's decision-making. Traditional trust prediction models rely on pairwise correlations to infer potential relationships between users. However, in the real world, interactions between users are usually complicated rather than pairwise only. Hypergraphs offer a flexible approach to modeling these complex high-order correlations (not just pairwise connections), since hypergraphs can leverage hyperedeges to link more than two nodes. However, most hypergraph-based methods are generic and cannot be well applied to the trust prediction task. In this paper, we propose an Adaptive Hypergraph Network for Trust Prediction (AHNTP), a novel approach that improves trust prediction accuracy by using higher-order correlations. AHNTP utilizes Motif-based PageRank to capture high-order social influence information. In addition, it constructs hypergroups from both node-level and structure-level attributes to incorporate complex correlation information. Furthermore, AHNTP leverages adaptive hypergraph Graph Convolutional Network (GCN) layers and multilayer perceptrons (MLPs) to generate comprehensive user embeddings, facilitating trust relationship prediction. To enhance model generalization and robustness, we introduce a novel supervised contrastive learning loss for optimization. Extensive experiments demonstrate the superiority of our model over the state-of-the-art approaches in terms of trust prediction accuracy. The source code of this work can be accessed via https://github.com/Sherry-XU1995/AHNTP.

Xiaojun Jia, Yihao Huang, Yang Liu et al.

This paper introduces the Global Challenge for Safe and Secure Large Language Models (LLMs), a pioneering initiative organized by AI Singapore (AISG) and the CyberSG R&D Programme Office (CRPO) to foster the development of advanced defense mechanisms against automated jailbreaking attacks. With the increasing integration of LLMs in critical sectors such as healthcare, finance, and public administration, ensuring these models are resilient to adversarial attacks is vital for preventing misuse and upholding ethical standards. This competition focused on two distinct tracks designed to evaluate and enhance the robustness of LLM security frameworks. Track 1 tasked participants with developing automated methods to probe LLM vulnerabilities by eliciting undesirable responses, effectively testing the limits of existing safety protocols within LLMs. Participants were challenged to devise techniques that could bypass content safeguards across a diverse array of scenarios, from offensive language to misinformation and illegal activities. Through this process, Track 1 aimed to deepen the understanding of LLM vulnerabilities and provide insights for creating more resilient models.