Yihua Shao

Chongcong Jiang, Tianxingjian Ding, Chuhan Song et al.

Promptable segmentation foundation models such as SAM3 have demonstrated strong generalization capabilities through interactive and concept-based prompting. However, their direct applicability to medical image segmentation remains limited by severe domain shifts, the absence of privileged spatial prompts, and the need to reason over complex anatomical and volumetric structures. Here we present Medical SAM3, a foundation model for universal prompt-driven medical image segmentation, obtained by fully fine-tuning SAM3 on large-scale, heterogeneous 2D and 3D medical imaging datasets with paired segmentation masks and text prompts. Through a systematic analysis of vanilla SAM3, we observe that its performance degrades substantially on medical data, with its apparent competitiveness largely relying on strong geometric priors such as ground-truth-derived bounding boxes. These findings motivate full model adaptation beyond prompt engineering alone. By fine-tuning SAM3's model parameters on 33 datasets spanning 10 medical imaging modalities, Medical SAM3 acquires robust domain-specific representations while preserving prompt-driven flexibility. Extensive experiments across organs, imaging modalities, and dimensionalities demonstrate consistent and significant performance gains, particularly in challenging scenarios characterized by semantic ambiguity, complex morphology, and long-range 3D context. Our results establish Medical SAM3 as a universal, text-guided segmentation foundation model for medical imaging and highlight the importance of holistic model adaptation for achieving robust prompt-driven segmentation under severe domain shift. Code and model will be made available at https://github.com/AIM-Research-Lab/Medical-SAM3.

Run Ling, Ke Cao, Jian Lu et al.

Multi-subject video generation aims to synthesize videos from textual prompts and multiple reference images, ensuring that each subject preserves natural scale and visual fidelity. However, current methods face two challenges: scale inconsistency, where variations in subject size lead to unnatural generation, and permutation sensitivity, where the order of reference inputs causes subject distortion. In this paper, we propose MoFu, a unified framework that tackles both challenges. For scale inconsistency, we introduce Scale-Aware Modulation (SMO), an LLM-guided module that extracts implicit scale cues from the prompt and modulates features to ensure consistent subject sizes. To address permutation sensitivity, we present a simple yet effective Fourier Fusion strategy that processes the frequency information of reference features via the Fast Fourier Transform to produce a unified representation. Besides, we design a Scale-Permutation Stability Loss to jointly encourage scale-consistent and permutation-invariant generation. To further evaluate these challenges, we establish a dedicated benchmark with controlled variations in subject scale and reference permutation. Extensive experiments demonstrate that MoFu significantly outperforms existing methods in preserving natural scale, subject fidelity, and overall visual quality.

Yihong Huang, Fei Ma, Yihua Shao et al.

Vision token pruning has proven to be an effective acceleration technique for the efficient Vision Language Model (VLM). However, existing pruning methods demonstrate excellent performance preservation in visual question answering (VQA) and suffer substantial degradation on visual grounding (VG) tasks. Our analysis of the VLM's processing pipeline reveals that strategies utilizing global semantic similarity and attention scores lose the global spatial reference frame, which is derived from the interactions of tokens' positional information. Motivated by these findings, we propose $\text{Nüwa}$, a two-stage token pruning framework that enables efficient feature aggregation while maintaining spatial integrity. In the first stage, after the vision encoder, we apply three operations, namely separation, alignment, and aggregation, which are inspired by swarm intelligence algorithms to retain information-rich global spatial anchors. In the second stage, within the LLM, we perform text-guided pruning to retain task-relevant visual tokens. Extensive experiments demonstrate that $\text{Nüwa}$ achieves SOTA performance on multiple VQA benchmarks (from 94% to 95%) and yields substantial improvements on visual grounding tasks (from 7% to 47%).

Zhou Hong, Rongsheng Hu, Yicheng Di et al.

Image style transfer aims to integrate the visual patterns of a specific artistic style into a content image while preserving its content structure. Existing methods mainly rely on the generative adversarial network (GAN) or stable diffusion (SD). GAN-based approaches using CNNs or Transformers struggle to jointly capture local and global dependencies, leading to artifacts and disharmonious patterns. SD-based methods reduce such issues but often fail to preserve content structures and suffer from slow inference. To address these issues, we revisit GAN and propose a mamba-based generator, termed as StyMam, to produce high-quality stylized images without introducing artifacts and disharmonious patterns. Specifically, we introduce a mamba-based generator with a residual dual-path strip scanning mechanism and a channel-reweighted spatial attention module. The former efficiently captures local texture features, while the latter models global dependencies. Finally, extensive qualitative and quantitative experiments demonstrate that the proposed method outperforms state-of-the-art algorithms in both quality and speed.