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Jiawen Li, Tian Guan, Huijuan Shi et al.

Foundation models are reshaping computational pathology, yet their capabilities remain shaped by pretraining objectives, data sources, and spatial scales, fragmenting complementary expertise across separate backbones. Here we present ALICE, a unified foundation model trained through multi-stage agglomerative distillation that sequentially distills eight vision-only, vision-language, and slide-level teacher models into dedicated modules of a single backbone. ALICE is pretrained on 24,985,184 tile-level pathology images and 155,604 high-resolution images, and evaluated across 21 task scenarios, 96 downstream tasks, and 48 data sources, spanning region-of-interest tissue analysis, vision-language multimodal evaluation, and whole-slide clinical assessment. In all three evaluation settings, ALICE achieved the best average rank among task-matched pathology foundation models. These results demonstrate that agglomerative distillation can consolidate complementary capabilities from specialized models into a unified backbone for broad computational pathology applications. The model is available at https://github.com/WonderLandxD/ALICE.

Shengyi Hua, Kangzhe Hu, Conghui He et al.

Recent reasoning-centric Large Language Models (LLMs) have made significant strides, yet they predominantly operate on a passive-inference pattern that assumes complete information. In contrast, real-world clinical intelligence is inherently an iterative investigative process requiring strategic evidence acquisition. To bridge this gap, we formalize medical diagnosis as an Iterative Evidence-Seeking Task. We leverage Reinforcement Learning with Verifiable Rewards (RLVR) to elicit intrinsic reasoning within a closed-loop environment, guided by a novel suite of rewards that enforce diagnostic precision and examination consistency. To facilitate this, we introduce the Retrieval-Augmented Generation-based Examination Simulator (RAGES), a high-fidelity clinical oracle that provides realistic, knowledge-grounded follow-up evidence. Empirical results across diverse datasets demonstrate that our framework enables LLMs to transition from passive responders to autonomous assistants. Notably, our model demonstrates comparable performance to larger and reasoning-enhanced baselines, while RAGES proves superior to vanilla LLMs in generating biologically plausible clinical feedback.

Lei Shi, Di Wang, Harry Tran et al.

Recommendation systems, from traditional multi-stage to recent unified generative architectures, face challenges in incorporating diverse contextual signals, such as trending topics, breaking news, cultural events, and cross-surface user activities, into their ranking pipelines. These systems are designed to consume structured behavioral signals with consistent schemas, and lack the reasoning capability to naturally process unstructured or heterogeneously formatted contextual information. Incorporating such signals typically requires feature engineering, bespoke data pipelines, and carefully tuned heuristics. In this paper, we present an LLM-powered agentic recommendation system designed for Connected TV (CTV) content discovery that addresses these limitations. Our system leverages the reasoning capabilities of large language models to naturally process and synthesize diverse signals across varying schemas and structures, eliminating much of the manual integration inherent in traditional ranking and retrieval systems. Recognizing that current LLM-based solutions still fall short of traditional machine learning models in several recommendation tasks, including retrieval efficiency, personalization precision, and scalability, we adopt an agentic architecture that orchestrates specialized components, allowing each sub-task to be handled by the most suitable method, whether LLM-based or traditional ML. The main contribution of this work is our engineering approach to successfully overcoming the practical limitations of enabling LLM for recommendation, particularly inference latency. We share insights from our work and discuss the trade-offs and lessons learned in building a hybrid system that combines the flexibility of LLMs with the performance of established recommendation techniques.

Bo Huang, Fengxiang Li, Hao Xu et al.

We present KAT-Coder-V2.5, a coding-focused agentic model trained to act autonomously inside real, executable repositories rather than as a single-turn code generator. Its capability is bottlenecked less by model scale than by the scarcity of reproducible environments, verifiable rewards, and high-value trajectories, which we address with an end-to-end agentic post-training framework. AutoBuilder reconstructs multilingual repositories into sandboxed environments with fail-to-pass and pass-to-pass verification at scale, from which we regenerate self-contained task specifications, recover near-miss trajectories, and distill supervision through process-aware filtering, while KwaiClawEnv synthesizes large-scale tool-use trajectories from executable services and real task seeds. We further scale reinforcement learning with harness randomization, a reliability-hardened sandbox, an asymmetric actor--critic PPO with hindsight-augmented value estimation, and a harness-oriented reward framework, and unify SWE, Agent-Claw, and WebCoding experts via Multi-Teacher On-Policy Distillation. Across six software-engineering and agentic benchmarks, KAT-Coder-V2.5 delivers the best agentic tool-use result on PinchBench and ranks second only to the frontier Opus 4.8 on repository-level software engineering. Our service is available at https://streamlake.com/product/kat-coder.

Cheng He, Kunyu Peng, Shangen Han et al.

Cross-subject EEG stress detection remains challenging because discriminative stress-related patterns are both subject-dependent and frequency-specific. Conventional Riemannian methods model spatial covariance mainly in the time domain, overlooking neural oscillations that are critical for high-level cognitive state decoding, while standard temporal tokenization often fragments inter-slice temporal coherence. To address these limitations, we propose \method{}, an Intra-Inter Riemannian Manifold Attention Network for EEG-based stress detection. \method{} constructs spatial covariance matrices independently at each frequency point and maps them to the SPD tangent space, preserving channel-wise geometry together with frequency-specific discriminative cues. It further introduces frequency cluster aggregation to select informative spectral components and reduce redundancy by forming compact, data-driven frequency clusters aligned with EEG rhythms. Finally, an intra-inter slice attention module adaptively integrates local slice-level spectral dynamics and global temporal context across EEG sequences. Experiments on three datasets show that \method{} consistently outperforms five state-of-the-art baselines, achieving up to 82.78\% balanced accuracy while remaining efficient with only 1.60M parameters and 31.95M FLOPs.

Hao Liang, Qifeng Cai, Yibo Lin et al.

The quality of training data fundamentally determines the capabilities of large language models (LLMs), yet no unified benchmark exists to measure how well LLMs, agents, and data-centric workflows actually prepare training data end to end. We view LLM-driven data preparation as comprising two complementary capabilities: data construction, which transforms raw sources into supervised training data, and data quality evaluation, which predicts the training value of candidate datasets before downstream training; throughout, "quality" refers to downstream training utility rather than surface-level textual properties. We introduce DataPrep-Bench, the first unified benchmark that jointly evaluates both capabilities under a shared downstream-grounded protocol over six domains and multiple base models. For data construction, methods consume identical raw sources and are scored by fine-tuning a base model on their outputs jointly with Dolly-15k; alongside this track we release Data-Construction-Skill, a skill-guided agent that lifts the Dolly-only baseline by nearly 20 points absolute on Llama-3.1-8B Finance and is competitive with the strongest agent- and DataFlow-based methods in knowledge-extraction-dense domains. For data quality evaluation, scoring functions are scored by Pearson correlation with downstream performance on a shared candidate pool; we release the Distributional Alignment Score (DAS), a distribution-based evaluator that uses MMD between a candidate dataset and a domain proxy. DAS attains the strongest cross-model correlation in four of six domains and is the only metric clearing r > 0.70 simultaneously in Math, Science, and Medical, outperforming existing quality-, diversity-, and heuristic-based evaluators. DataPrep-Bench provides a unified, downstream-grounded framework for measuring progress on both capabilities as co-equal targets of LLM-driven data preparation.