Hao Wu

Qin Lei, Hao Wu

Virtual contrast enhancement (VCE) synthesizes enhanced breast MR images from pre-contrast acquisitions. Modern latent generators offer strong image priors, but their bounded natural-image autoencoders conflict with the non-canonical intensity scale of MRI. We show that the upper bound can alter radiomic fidelity before generation, while scaling source and target independently creates a coordinate inconsistency. We propose Predictive Enhancement Calibration (PEC), which represents each pair in a shared, case-adaptive coordinate during training and predicts its unavailable upper endpoint from the pre-contrast image at inference. We integrate PEC with a pretrained FLUX latent flow transformer via parameter-efficient reference conditioning. Target round trips first isolate representation loss before generation; near-matched conditional models then compare PEC with fixed-wide and separate coordinates under comparable training budgets and backbone settings. On the fixed internal MAMA100 development cohort, PEC improves all eight point estimates in this source-only VCE setting, with paired evidence strongest for MSE and LPIPS.\noindent\textbf{Code:} https://github.com/tanlei0/pec-breast-mri-vce

Hao Wu, Shoucheng Song, Chang Yao et al.

Multi-Agent Debate (MAD) improves the reasoning performance of Large Language Models (LLMs) through multi-round interaction. However, LLMs in MAD are highly susceptible to blind conformity. Existing individual evaluation methods, typically based on confidence or perplexity, fail to reflect the correctness of reasoning and may even exacerbate blind conformity. To address this, we shift the perspective from individual evaluation to group interaction. We define mutual referencing among LLMs as \textbf{Debate Relationships} and recognize that regulating these relationships is the key to mitigating blind conformity. In this paper, we propose a novel framework for \textbf{D}ynamically r\textbf{E}gulating deb\textbf{A}te \textbf{R}elationships (DEAR) from the group perspective. At first, DEAR quantifies consensus and divergence as \textit{group evidence} to capture the debate state. Then, DEAR operates through three stages: 1) What: perceiving group consultation tendency and uncertainty; 2) Who: introducing a Selection RL-Agent to dynamically select reference peers; and 3) How: adopting a Behavior RL-Agent to adaptively adjust generation behaviors. Notably, we formulate the execution of the two RL-Agents as a sequential decision-making process, jointly optimizing via multi-agent reinforcement learning. Extensive experiments demonstrate that DEAR achieves superior performance while significantly reducing token consumption.