NANAAug 1, 2016

On the Adjoint Operator in Photoacoustic Tomography

arXiv:1602.02027126 citations
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This work addresses the need for efficient adjoint operators in variational PAT reconstruction, which is crucial for handling incomplete data in practical imaging scenarios.

The paper provides a mathematical derivation and numerical implementation of the adjoint operator for photoacoustic tomography (PAT) forward model, enabling variational image reconstruction with incomplete or subsampled data. The adjoint is implemented using a k-space time domain wave propagation solver and demonstrated on 2D and 3D examples with inhomogeneous sound speed.

Photoacoustic Tomography (PAT) is an emerging biomedical "imaging from coupled physics" technique, in which the image contrast is due to optical absorption, but the information is carried to the surface of the tissue as ultrasound pulses. Many algorithms and formulae for PAT image reconstruction have been proposed for the case when a complete data set is available. In many practical imaging scenarios, however, it is not possible to obtain the full data, or the data may be sub-sampled for faster data acquisition. In such cases, image reconstruction algorithms that can incorporate prior knowledge to ameliorate the loss of data are required. Hence, recently there has been an increased interest in using variational image reconstruction. A crucial ingredient for the application of these techniques is the adjoint of the PAT forward operator, which is described in this article from physical, theoretical and numerical perspectives. First, a simple mathematical derivation of the adjoint of the PAT forward operator in the continuous framework is presented. Then, an efficient numerical implementation of the adjoint using a k-space time domain wave propagation model is described and illustrated in the context of variational PAT image reconstruction, on both 2D and 3D examples including inhomogeneous sound speed. The principal advantage of this analytical adjoint over an algebraic adjoint (obtained by taking the direct adjoint of the particular numerical forward scheme used) is that it can be implemented using currently available fast wave propagation solvers.

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