HCCYNov 13, 2017

COMBINE: a novel drug discovery platform designed to capture insight and experience of users

arXiv:1711.04513v11 citations
Originality Synthesis-oriented
AI Analysis

This addresses inefficiencies for drug discovery researchers by integrating tools, though it appears incremental as it builds on existing concepts of connected applications.

The paper tackles the problem of lost researcher insight and experience in drug discovery due to disconnected software by introducing COMBINE, a user-centric platform that connects applications to capture and utilize this knowledge, demonstrating its use for data organization, sharing, analysis, and visualization with publicly available data.

The insight and experience gained by a researcher are often lost because the current productive and analytics software are inherently data-centric, disconnected, and scattered. The connected nature of insight and experience can be captured if the applications themselves are connected. How connected applications concept is implemented in COnstruct cheMical and BIological NEtwork (COMBINE), a novel user-centric drug discovery platform, is described. Using publicly available data, how COMBINE users capture insight and experience is explained, and how COMBINE users perform data organization, data sharing, data analysis, and data visualization is illustrated.

Foundations

The foundational work for this paper's niche, ranked by how specifically the neighbourhood builds on it — not by global fame.

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