Classification of postoperative surgical site infections from blood measurements with missing data using recurrent neural networks
This addresses a domain-specific problem for healthcare by improving infection detection from incomplete clinical data, but it is incremental as it builds on existing RNN methods.
The paper tackled the problem of detecting surgical site infections from blood measurements with missing data by exploring imputation strategies and using a Gated Recurrent Unit with Decay architecture, achieving results compared across different RNN-based classifiers.
Clinical measurements that can be represented as time series constitute an important fraction of the electronic health records and are often both uncertain and incomplete. Recurrent neural networks are a special class of neural networks that are particularly suitable to process time series data but, in their original formulation, cannot explicitly deal with missing data. In this paper, we explore imputation strategies for handling missing values in classifiers based on recurrent neural network (RNN) and apply a recently proposed recurrent architecture, the Gated Recurrent Unit with Decay, specifically designed to handle missing data. We focus on the problem of detecting surgical site infection in patients by analyzing time series of their blood sample measurements and we compare the results obtained with different RNN-based classifiers.