Determining Multifunctional Genes and Diseases in Human Using Gene Ontology
This work addresses the need for better understanding gene-disease links in biomedical research, but it appears incremental as it builds on a previous study.
The authors tackled the problem of identifying multifunctional genes and their disease associations by leveraging Gene Ontology annotations, resulting in a method to determine these relationships for potential applications in healthcare and diagnostics.
The study of human genes and diseases is very rewarding and can lead to improvements in healthcare, disease diagnostics and drug discovery. In this paper, we further our previous study on gene disease relationship specifically with the multifunctional genes. We investigate the multifunctional gene disease relationship based on the published molecular function annotations of genes from the Gene Ontology which is the most comprehensive source on gene functions.