Deep MR Brain Image Super-Resolution Using Spatio-Structural Priors
This work addresses the need for high-resolution MR images in medical diagnostics, offering an incremental improvement by integrating novel priors into existing network architectures.
The paper tackles the problem of enhancing low-resolution Magnetic Resonance (MR) brain images for accurate diagnostics by proposing a deep learning method that incorporates spatio-structural priors, resulting in significant practical gains in SNR and image quality measures compared to existing state-of-the-art methods.
High resolution Magnetic Resonance (MR) images are desired for accurate diagnostics. In practice, image resolution is restricted by factors like hardware and processing constraints. Recently, deep learning methods have been shown to produce compelling state-of-the-art results for image enhancement/super-resolution. Paying particular attention to desired hi-resolution MR image structure, we propose a new regularized network that exploits image priors, namely a low-rank structure and a sharpness prior to enhance deep MR image super-resolution (SR). Our contributions are then incorporating these priors in an analytically tractable fashion \color{black} as well as towards a novel prior guided network architecture that accomplishes the super-resolution task. This is particularly challenging for the low rank prior since the rank is not a differentiable function of the image matrix(and hence the network parameters), an issue we address by pursuing differentiable approximations of the rank. Sharpness is emphasized by the variance of the Laplacian which we show can be implemented by a fixed feedback layer at the output of the network. As a key extension, we modify the fixed feedback (Laplacian) layer by learning a new set of training data driven filters that are optimized for enhanced sharpness. Experiments performed on publicly available MR brain image databases and comparisons against existing state-of-the-art methods show that the proposed prior guided network offers significant practical gains in terms of improved SNR/image quality measures. Because our priors are on output images, the proposed method is versatile and can be combined with a wide variety of existing network architectures to further enhance their performance.