Spatio-temporal Multi-task Learning for Cardiac MRI Left Ventricle Quantification
This work provides an automated and robust solution for cardiac LV quantification, which is crucial for cardiologists to diagnose cardiovascular diseases, reducing the time-consuming and variable manual contouring process.
This paper proposes a spatio-temporal multi-task learning approach to quantify cardiac left ventricle (LV) morphology, regional-wall thickness (RWT), and detect cardiac phase from 3D Cine-MR image sequences. The method achieved high prediction accuracy with an average mean absolute error (MAE) of 129 mm^2 for LV/Myo cavity, 1.23 mm for RWT, 1.76 mm for LV dimensions, and a 9.0% error rate for phase classification.
Quantitative assessment of cardiac left ventricle (LV) morphology is essential to assess cardiac function and improve the diagnosis of different cardiovascular diseases. In current clinical practice, LV quantification depends on the measurement of myocardial shape indices, which is usually achieved by manual contouring of the endo- and epicardial. However, this process subjected to inter and intra-observer variability, and it is a time-consuming and tedious task. In this paper, we propose a spatio-temporal multi-task learning approach to obtain a complete set of measurements quantifying cardiac LV morphology, regional-wall thickness (RWT), and additionally detecting the cardiac phase cycle (systole and diastole) for a given 3D Cine-magnetic resonance (MR) image sequence. We first segment cardiac LVs using an encoder-decoder network and then introduce a multitask framework to regress 11 LV indices and classify the cardiac phase, as parallel tasks during model optimization. The proposed deep learning model is based on the 3D spatio-temporal convolutions, which extract spatial and temporal features from MR images. We demonstrate the efficacy of the proposed method using cine-MR sequences of 145 subjects and comparing the performance with other state-of-the-art quantification methods. The proposed method obtained high prediction accuracy, with an average mean absolute error (MAE) of 129 $mm^2$, 1.23 $mm$, 1.76 $mm$, Pearson correlation coefficient (PCC) of 96.4%, 87.2%, and 97.5% for LV and myocardium (Myo) cavity regions, 6 RWTs, 3 LV dimensions, and an error rate of 9.0\% for phase classification. The experimental results highlight the robustness of the proposed method, despite varying degrees of cardiac morphology, image appearance, and low contrast in the cardiac MR sequences.