Brain Modelling as a Service: The Virtual Brain on EBRAINS
This addresses the need for scalable and collaborative tools in brain science research, particularly for large cohort studies and clinical applications, though it is incremental as it builds on existing TVB technology.
The paper introduces The Virtual Brain (TVB) as an open-source cloud ecosystem on EBRAINS, providing services for constructing, simulating, and analyzing brain network models to facilitate reproducible research and clinical translation.
The Virtual Brain (TVB) is now available as open-source cloud ecosystem on EBRAINS, a shared digital research platform for brain science. It offers services for constructing, simulating and analysing brain network models (BNMs) including the TVB network simulator; magnetic resonance imaging (MRI) processing pipelines to extract structural and functional connectomes; multiscale co-simulation of spiking and large-scale networks; a domain specific language for automatic high-performance code generation from user-specified models; simulation-ready BNMs of patients and healthy volunteers; Bayesian inference of epilepsy spread; data and code for mouse brain simulation; and extensive educational material. TVB cloud services facilitate reproducible online collaboration and discovery of data assets, models, and software embedded in scalable and secure workflows, a precondition for research on large cohort data sets, better generalizability and clinical translation.