Improving Tuberculosis (TB) Prediction using Synthetically Generated Computed Tomography (CT) Images
This work addresses the challenge of diagnosing TB in low-resource settings where CT scans are scarce, though it is incremental as it builds on existing image generation methods.
The paper tackled the problem of limited CT scan availability for tuberculosis (TB) diagnosis by generating synthetic CT images from X-rays, resulting in a 7.50% improvement in TB identification accuracy and up to 12.16% better property distinction compared to X-ray baselines.
The evaluation of infectious disease processes on radiologic images is an important and challenging task in medical image analysis. Pulmonary infections can often be best imaged and evaluated through computed tomography (CT) scans, which are often not available in low-resource environments and difficult to obtain for critically ill patients. On the other hand, X-ray, a different type of imaging procedure, is inexpensive, often available at the bedside and more widely available, but offers a simpler, two dimensional image. We show that by relying on a model that learns to generate CT images from X-rays synthetically, we can improve the automatic disease classification accuracy and provide clinicians with a different look at the pulmonary disease process. Specifically, we investigate Tuberculosis (TB), a deadly bacterial infectious disease that predominantly affects the lungs, but also other organ systems. We show that relying on synthetically generated CT improves TB identification by 7.50% and distinguishes TB properties up to 12.16% better than the X-ray baseline.