TorchDrug: A Powerful and Flexible Machine Learning Platform for Drug Discovery
This provides a tool for machine learning researchers to accelerate drug discovery, though it is incremental as it builds on existing methods.
The authors tackled the lack of domain knowledge, benchmarks, and data pipelines hindering machine learning in drug discovery by developing TorchDrug, a platform that benchmarks tasks like molecular property prediction and achieves state-of-the-art results using techniques such as geometric deep learning.
Machine learning has huge potential to revolutionize the field of drug discovery and is attracting increasing attention in recent years. However, lacking domain knowledge (e.g., which tasks to work on), standard benchmarks and data preprocessing pipelines are the main obstacles for machine learning researchers to work in this domain. To facilitate the progress of machine learning for drug discovery, we develop TorchDrug, a powerful and flexible machine learning platform for drug discovery built on top of PyTorch. TorchDrug benchmarks a variety of important tasks in drug discovery, including molecular property prediction, pretrained molecular representations, de novo molecular design and optimization, retrosynthsis prediction, and biomedical knowledge graph reasoning. State-of-the-art techniques based on geometric deep learning (or graph machine learning), deep generative models, reinforcement learning and knowledge graph reasoning are implemented for these tasks. TorchDrug features a hierarchical interface that facilitates customization from both novices and experts in this domain. Tutorials, benchmark results and documentation are available at https://torchdrug.ai. Code is released under Apache License 2.0.