Imaging the time series of one single referenced EEG electrode for Epileptic Seizures Risk Analysis
This work addresses seizure risk analysis for epileptic patients but is incremental, building on existing methods without major innovations.
The study tackled seizure forecasting in refractory epilepsy by transforming single-electrode EEG time series into images using known methods and using a CNN's softmax layer output for likelihood estimation, achieving improved performance with patient-specific thresholds.
The time series captured by a single scalp electrode (plus the reference electrode) of refractory epileptic patients is used to forecast seizures susceptibility. The time series is preprocessed, segmented, and each segment transformed into an image, using three different known methods: Recurrence Plot, Gramian Angular Field, Markov Transition Field. The likelihood of the occurrence of a seizure in a future predefined time window is computed by averaging the output of the softmax layer of a CNN, differently from the usual consideration of the output of the classification layer. By thresholding this likelihood, seizure forecasting has better performance. Interestingly, for almost every patient, the best threshold was different from 50%. The results show that this technique can predict with good results for some seizures and patients. However, more tests, namely more patients and more seizures, are needed to better understand the real potential of this technique.