Adaptive Weighted Multiview Kernel Matrix Factorization with its application in Alzheimer's Disease Analysis -- A clustering Perspective
This work addresses Alzheimer's disease analysis by improving clustering performance across image and genetic data, though it appears incremental as it builds on existing matrix factorization techniques.
The authors tackled the problem of clustering Alzheimer's disease data from multiple modalities by proposing an adaptive weighted multiview kernel matrix factorization method, which achieved better prediction accuracy on the ADNI dataset compared to linear approaches.
Recent technology and equipment advancements provide with us opportunities to better analyze Alzheimer's disease (AD), where we could collect and employ the data from different image and genetic modalities that may potentially enhance the predictive performance. To perform better clustering in AD analysis, in this paper we propose a novel model to leverage data from all different modalities/views, which can learn the weights of each view adaptively. Different from previous vanilla Non-negative Matrix Factorization which assumes data is linearly separable, we propose a simple yet efficient method based on kernel matrix factorization, which is not only able to deal with non-linear data structure but also can achieve better prediction accuracy. Experimental results on ADNI dataset demonstrate the effectiveness of our proposed method, which indicate promising prospects of kernel application in AD analysis.