Unsupervised Adaptation of Polyp Segmentation Models via Coarse-to-Fine Self-Supervision
This addresses privacy and security concerns in medical imaging by enabling adaptation without source data, though it is incremental as it builds on existing SFDA approaches.
The paper tackles the problem of Source-Free Domain Adaptation (SFDA) for polyp segmentation, where annotated source data is unavailable, by proposing RPANet with coarse-to-fine self-supervision, achieving significant performance improvements over state-of-the-art methods on three cross-domain tasks.
Unsupervised Domain Adaptation~(UDA) has attracted a surge of interest over the past decade but is difficult to be used in real-world applications. Considering the privacy-preservation issues and security concerns, in this work, we study a practical problem of Source-Free Domain Adaptation (SFDA), which eliminates the reliance on annotated source data. Current SFDA methods focus on extracting domain knowledge from the source-trained model but neglects the intrinsic structure of the target domain. Moreover, they typically utilize pseudo labels for self-training in the target domain, but suffer from the notorious error accumulation problem. To address these issues, we propose a new SFDA framework, called Region-to-Pixel Adaptation Network~(RPANet), which learns the region-level and pixel-level discriminative representations through coarse-to-fine self-supervision. The proposed RPANet consists of two modules, Foreground-aware Contrastive Learning (FCL) and Confidence-Calibrated Pseudo-Labeling (CCPL), which explicitly address the key challenges of ``how to distinguish'' and ``how to refine''. To be specific, FCL introduces a supervised contrastive learning paradigm in the region level to contrast different region centroids across different target images, which efficiently involves all pseudo labels while robust to noisy samples. CCPL designs a novel fusion strategy to reduce the overconfidence problem of pseudo labels by fusing two different target predictions without introducing any additional network modules. Extensive experiments on three cross-domain polyp segmentation tasks reveal that RPANet significantly outperforms state-of-the-art SFDA and UDA methods without access to source data, revealing the potential of SFDA in medical applications.