Deep Learning-based Intraoperative MRI Reconstruction
This addresses the need for faster, high-quality MRI reconstructions during brain surgery, but it is incremental as it builds on existing deep learning methods applied to a specific medical imaging domain.
The study tackled the problem of reconstructing accelerated intraoperative MRI during brain tumor surgery using a deep learning model, finding that it was favored over conventional compressed sense reconstruction in 33/40 to 39/40 cases for two readers, with higher scores in 72% of cases for those readers, though it had artifacts like striping and reduced signal.
Purpose: To evaluate the quality of deep learning reconstruction for prospectively accelerated intraoperative magnetic resonance imaging (iMRI) during resective brain tumor surgery. Materials and Methods: Accelerated iMRI was performed during brain surgery using dual surface coils positioned around the area of resection. A deep learning (DL) model was trained on the fastMRI neuro dataset to mimic the data from the iMRI protocol. Evaluation was performed on imaging material from 40 patients imaged between 01.11.2021 - 01.06.2023 that underwent iMRI during tumor resection surgery. A comparative analysis was conducted between the conventional compressed sense (CS) method and the trained DL reconstruction method. Blinded evaluation of multiple image quality metrics was performed by two working neuro-radiologists and a working neurosurgeon on a 1 to 5 Likert scale (1=non diagnostic, 2=poor, 3=acceptable, 4=good, 5=excellent), and the favored reconstruction variant. Results: The DL reconstruction was strongly favored or favored over the CS reconstruction for 33/40, 39/40, and 8/40 of cases for reader 1, 2, and 3, respectively. Two of three readers consistently assigned higher ratings for the DL reconstructions, and the DL reconstructions had a higher score than their respective CS counterparts for 72%, 72%, and 14% of the cases for reader 1, 2, and 3, respectively. Still, the DL reconstructions exhibited shortcomings such as a striping artifact and reduced signal. Conclusion: DL shows promise to allow for high-quality reconstructions of intraoperative MRI with equal to or improved perceived spatial resolution, signal-to-noise ratio, diagnostic confidence, diagnostic conspicuity, and spatial resolution compared to compressed sense.