Depth-induced Saliency Comparison Network for Diagnosis of Alzheimer's Disease via Jointly Analysis of Visual Stimuli and Eye Movements
This work addresses the problem of non-invasive biomarker detection for Alzheimer's Disease diagnosis, but it appears incremental as it builds on existing methods for eye movement analysis.
The paper tackles early diagnosis of Alzheimer's Disease by analyzing eye movements under visual stimuli, proposing a Depth-induced Saliency Comparison Network (DISCN) that achieves consistent validity in classifying eye movements between AD patients and normal controls.
Early diagnosis of Alzheimer's Disease (AD) is very important for following medical treatments, and eye movements under special visual stimuli may serve as a potential non-invasive biomarker for detecting cognitive abnormalities of AD patients. In this paper, we propose an Depth-induced saliency comparison network (DISCN) for eye movement analysis, which may be used for diagnosis the Alzheimers disease. In DISCN, a salient attention module fuses normal eye movements with RGB and depth maps of visual stimuli using hierarchical salient attention (SAA) to evaluate comprehensive saliency maps, which contain information from both visual stimuli and normal eye movement behaviors. In addition, we introduce serial attention module (SEA) to emphasis the most abnormal eye movement behaviors to reduce personal bias for a more robust result. According to our experiments, the DISCN achieves consistent validity in classifying the eye movements between the AD patients and normal controls.