BOston Neonatal Brain Injury Data for Hypoxic Ischemic Encephalopathy (BONBID-HIE): II. 2-year Neurocognitive Outcome and NICU Outcome
This dataset aims to improve biomarker development for HIE prognosis, benefiting clinicians and researchers in neonatal care, but it is incremental as it builds on an existing dataset.
The paper introduces the second release of the BONBID-HIE dataset, which includes MRI and clinical data from 237 patients to address the challenge of predicting neurocognitive outcomes in newborns with Hypoxic Ischemic Encephalopathy, despite therapeutic advances.
Hypoxic Ischemic Encephalopathy (HIE) affects approximately 1-5/1000 newborns globally and leads to adverse neurocognitive outcomes in 30% to 50% of cases by two years of age. Despite therapeutic advances with Therapeutic Hypothermia (TH), prognosis remains challenging, highlighting the need for improved biomarkers. This paper introduces the second release of the Boston Neonatal Brain Injury Dataset for Hypoxic-Ischemic Encephalopathy (BONBID-HIE), an open-source, comprehensive MRI and clinical dataset featuring 237 patients, including NICU outcomes and 2-year neurocognitive outcomes from Massachusetts General Hospital and Boston Children's Hospital.