COMMA: Coordinate-aware Modulated Mamba Network for 3D Dispersed Vessel Segmentation
This addresses the challenge of accurate 3D vessel segmentation in medical imaging, which is essential for applications like diagnosis and treatment planning, though it appears incremental by building on existing Mamba-based methods.
The paper tackles the problem of 3D vascular structure segmentation by introducing COMMA, a network that improves spatial location awareness through global and local branches, achieving superior performance on six datasets with computational efficiency, especially for small vessels.
Accurate segmentation of 3D vascular structures is essential for various medical imaging applications. The dispersed nature of vascular structures leads to inherent spatial uncertainty and necessitates location awareness, yet most current 3D medical segmentation models rely on the patch-wise training strategy that usually loses this spatial context. In this study, we introduce the Coordinate-aware Modulated Mamba Network (COMMA) and contribute a manually labeled dataset of 570 cases, the largest publicly available 3D vessel dataset to date. COMMA leverages both entire and cropped patch data through global and local branches, ensuring robust and efficient spatial location awareness. Specifically, COMMA employs a channel-compressed Mamba (ccMamba) block to encode entire image data, capturing long-range dependencies while optimizing computational costs. Additionally, we propose a coordinate-aware modulated (CaM) block to enhance interactions between the global and local branches, allowing the local branch to better perceive spatial information. We evaluate COMMA on six datasets, covering two imaging modalities and five types of vascular tissues. The results demonstrate COMMA's superior performance compared to state-of-the-art methods with computational efficiency, especially in segmenting small vessels. Ablation studies further highlight the importance of our proposed modules and spatial information. The code and data will be open source at https://github.com/shigen-StoneRoot/COMMA.