CVMar 10, 2025

LLaVA-RadZ: Can Multimodal Large Language Models Effectively Tackle Zero-shot Radiology Recognition?

arXiv:2503.07487v26 citationsh-index: 11
Originality Incremental advance
AI Analysis

This work addresses the challenge of fine-grained medical image analysis for healthcare applications, representing an incremental improvement over existing MLLM approaches.

The paper tackles the problem of zero-shot radiology recognition by proposing LLaVA-RadZ, a framework that improves Multimodal Large Language Models (MLLMs) through feature alignment and domain knowledge integration, achieving performance comparable to CLIP-based methods.

Recently, Multimodal Large Language Models (MLLMs) have demonstrated exceptional capabilities in visual understanding and reasoning across various vision-language tasks. However, we found that MLLMs cannot process effectively from fine-grained medical image data in the traditional Visual Question Answering (VQA) pipeline, as they do not exploit the captured features and available medical knowledge fully, results in MLLMs usually performing poorly in zero-shot medical disease recognition. Fortunately, this limitation does not indicate that MLLMs are fundamentally incapable of addressing fine-grained recognition tasks. From a feature representation perspective, MLLMs demonstrate considerable potential for tackling such challenging problems. Thus, to address this challenge, we propose LLaVA-RadZ, a simple yet effective framework for zero-shot medical disease recognition via utilizing the existing MLLM features. Specifically, we design an end-to-end training strategy, termed Decoding-Side Feature Alignment Training (DFAT) to take advantage of the characteristics of the MLLM decoder architecture and incorporate modality-specific tokens tailored for different modalities. Additionally, we introduce a Domain Knowledge Anchoring Module (DKAM) to exploit the intrinsic medical knowledge of large models, which mitigates the category semantic gap in image-text alignment. Extensive experiments demonstrate that our LLaVA-RadZ significantly outperforms traditional MLLMs in zero-shot disease recognition, achieving the comparable performance to the well-established and highly-optimized CLIP-based approaches.

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