CVMay 5, 2025

Structure Causal Models and LLMs Integration in Medical Visual Question Answering

arXiv:2505.02703v111 citationsh-index: 31IEEE Transactions on Medical Imaging
Originality Incremental advance
AI Analysis

This work addresses bias in medical image-question answering for healthcare applications, representing an incremental improvement with a novel causal graph structure.

The authors tackled the problem of cross-modal bias in Medical Visual Question Answering (MedVQA) by proposing a causal inference framework, which significantly improved accuracy on three datasets and achieved true causal correlations.

Medical Visual Question Answering (MedVQA) aims to answer medical questions according to medical images. However, the complexity of medical data leads to confounders that are difficult to observe, so bias between images and questions is inevitable. Such cross-modal bias makes it challenging to infer medically meaningful answers. In this work, we propose a causal inference framework for the MedVQA task, which effectively eliminates the relative confounding effect between the image and the question to ensure the precision of the question-answering (QA) session. We are the first to introduce a novel causal graph structure that represents the interaction between visual and textual elements, explicitly capturing how different questions influence visual features. During optimization, we apply the mutual information to discover spurious correlations and propose a multi-variable resampling front-door adjustment method to eliminate the relative confounding effect, which aims to align features based on their true causal relevance to the question-answering task. In addition, we also introduce a prompt strategy that combines multiple prompt forms to improve the model's ability to understand complex medical data and answer accurately. Extensive experiments on three MedVQA datasets demonstrate that 1) our method significantly improves the accuracy of MedVQA, and 2) our method achieves true causal correlations in the face of complex medical data.

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