LGAISPMay 8, 2025

Cardioformer: Advancing AI in ECG Analysis with Multi-Granularity Patching and ResNet

arXiv:2505.05538v11 citationsh-index: 2Has CodeCanadian AI
Originality Incremental advance
AI Analysis

This work addresses automated cardiac disease diagnosis through improved ECG analysis, representing an incremental advance with strong specific gains.

The paper tackled ECG classification by proposing Cardioformer, a multi-granularity hybrid model that integrates cross-channel patching and self-attention, achieving AUROC scores of up to 96.34% on benchmark datasets and outperforming state-of-the-art baselines.

Electrocardiogram (ECG) classification is crucial for automated cardiac disease diagnosis, yet existing methods often struggle to capture local morphological details and long-range temporal dependencies simultaneously. To address these challenges, we propose Cardioformer, a novel multi-granularity hybrid model that integrates cross-channel patching, hierarchical residual learning, and a two-stage self-attention mechanism. Cardioformer first encodes multi-scale token embeddings to capture fine-grained local features and global contextual information and then selectively fuses these representations through intra- and inter-granularity self-attention. Extensive evaluations on three benchmark ECG datasets under subject-independent settings demonstrate that model consistently outperforms four state-of-the-art baselines. Our Cardioformer model achieves the AUROC of 96.34$\pm$0.11, 89.99$\pm$0.12, and 95.59$\pm$1.66 in MIMIC-IV, PTB-XL and PTB dataset respectively outperforming PatchTST, Reformer, Transformer, and Medformer models. It also demonstrates strong cross-dataset generalization, achieving 49.18% AUROC on PTB and 68.41% on PTB-XL when trained on MIMIC-IV. These findings underscore the potential of Cardioformer to advance automated ECG analysis, paving the way for more accurate and robust cardiovascular disease diagnosis. We release the source code at https://github.com/KMobin555/Cardioformer.

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