IVCVMay 14, 2025

DCSNet: A Lightweight Knowledge Distillation-Based Model with Explainable AI for Lung Cancer Diagnosis from Histopathological Images

arXiv:2505.09334v13 citationsh-index: 4
Originality Synthesis-oriented
AI Analysis

This work aims to improve early lung cancer detection in resource-constrained healthcare settings, though it is incremental as it applies existing knowledge distillation and XAI methods to a specific medical domain.

The paper tackled the problem of deploying deep learning for lung cancer diagnosis by addressing computational cost and lack of transparency, resulting in a lightweight model (DCSNet) that maintains high diagnostic performance using knowledge distillation and explainable AI techniques.

Lung cancer is a leading cause of cancer-related deaths globally, where early detection and accurate diagnosis are critical for improving survival rates. While deep learning, particularly convolutional neural networks (CNNs), has revolutionized medical image analysis by detecting subtle patterns indicative of early-stage lung cancer, its adoption faces challenges. These models are often computationally expensive and require significant resources, making them unsuitable for resource constrained environments. Additionally, their lack of transparency hinders trust and broader adoption in sensitive fields like healthcare. Knowledge distillation addresses these challenges by transferring knowledge from large, complex models (teachers) to smaller, lightweight models (students). We propose a knowledge distillation-based approach for lung cancer detection, incorporating explainable AI (XAI) techniques to enhance model transparency. Eight CNNs, including ResNet50, EfficientNetB0, EfficientNetB3, and VGG16, are evaluated as teacher models. We developed and trained a lightweight student model, Distilled Custom Student Network (DCSNet) using ResNet50 as the teacher. This approach not only ensures high diagnostic performance in resource-constrained settings but also addresses transparency concerns, facilitating the adoption of AI-driven diagnostic tools in healthcare.

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