IVAICVMay 20, 2025

XDementNET: An Explainable Attention Based Deep Convolutional Network to Detect Alzheimer Progression from MRI data

arXiv:2505.13906v15 citationsh-index: 8Has Code
Originality Incremental advance
AI Analysis

This work addresses the need for precise and explainable diagnosis of Alzheimer's disease, which is crucial for healthcare efficiency, but it appears incremental as it builds on existing deep learning methods with attention mechanisms.

The paper tackled Alzheimer's disease progression detection from MRI data by proposing XDementNET, an explainable attention-based deep convolutional network, achieving high accuracies up to 100% in binary classification and over 99% in multiclass tasks across multiple datasets.

A common neurodegenerative disease, Alzheimer's disease requires a precise diagnosis and efficient treatment, particularly in light of escalating healthcare expenses and the expanding use of artificial intelligence in medical diagnostics. Many recent studies shows that the combination of brain Magnetic Resonance Imaging (MRI) and deep neural networks have achieved promising results for diagnosing AD. Using deep convolutional neural networks, this paper introduces a novel deep learning architecture that incorporates multiresidual blocks, specialized spatial attention blocks, grouped query attention, and multi-head attention. The study assessed the model's performance on four publicly accessible datasets and concentrated on identifying binary and multiclass issues across various categories. This paper also takes into account of the explainability of AD's progression and compared with state-of-the-art methods namely Gradient Class Activation Mapping (GradCAM), Score-CAM, Faster Score-CAM, and XGRADCAM. Our methodology consistently outperforms current approaches, achieving 99.66\% accuracy in 4-class classification, 99.63\% in 3-class classification, and 100\% in binary classification using Kaggle datasets. For Open Access Series of Imaging Studies (OASIS) datasets the accuracies are 99.92\%, 99.90\%, and 99.95\% respectively. The Alzheimer's Disease Neuroimaging Initiative-1 (ADNI-1) dataset was used for experiments in three planes (axial, sagittal, and coronal) and a combination of all planes. The study achieved accuracies of 99.08\% for axis, 99.85\% for sagittal, 99.5\% for coronal, and 99.17\% for all axis, and 97.79\% and 8.60\% respectively for ADNI-2. The network's ability to retrieve important information from MRI images is demonstrated by its excellent accuracy in categorizing AD stages.

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