CVMay 21, 2025

On the Robustness of Medical Vision-Language Models: Are they Truly Generalizable?

arXiv:2505.15425v26 citationsh-index: 4
Originality Incremental advance
AI Analysis

This work addresses the robustness gap in MVLMs for medical image analysis, which is crucial for real-world clinical applications but is incremental as it builds on existing models with adaptation strategies.

The paper tackled the problem of medical vision-language models (MVLMs) lacking robustness under noisy or corrupted conditions common in clinical imaging, by introducing a corruption benchmark and proposing RobustMedCLIP, which improved robustness through few-shot tuning and low-rank adaptation while preserving generalization.

Medical Vision-Language Models (MVLMs) have achieved par excellence generalization in medical image analysis, yet their performance under noisy, corrupted conditions remains largely untested. Clinical imaging is inherently susceptible to acquisition artifacts and noise; however, existing evaluations predominantly assess generally clean datasets, overlooking robustness -- i.e., the model's ability to perform under real-world distortions. To address this gap, we first introduce MediMeta-C, a corruption benchmark that systematically applies several perturbations across multiple medical imaging datasets. Combined with MedMNIST-C, this establishes a comprehensive robustness evaluation framework for MVLMs. We further propose RobustMedCLIP, a visual encoder adaptation of a pretrained MVLM that incorporates few-shot tuning to enhance resilience against corruptions. Through extensive experiments, we benchmark 5 major MVLMs across 5 medical imaging modalities, revealing that existing models exhibit severe degradation under corruption and struggle with domain-modality tradeoffs. Our findings highlight the necessity of diverse training and robust adaptation strategies, demonstrating that efficient low-rank adaptation when paired with few-shot tuning, improves robustness while preserving generalization across modalities.

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