LGJun 19, 2025

Active MRI Acquisition with Diffusion Guided Bayesian Experimental Design

arXiv:2506.16237v1h-index: 34
Originality Incremental advance
AI Analysis

This work addresses the problem of reducing MRI scan times for clinical applications, representing an incremental improvement in adaptive acquisition methods.

The paper tackles the challenge of accelerating MRI acquisition without degrading image quality by proposing an active Bayesian experimental design method that uses diffusion models to adaptively select informative measurements, achieving faster acquisition times while maintaining high-fidelity reconstruction and analysis tasks.

A key challenge in maximizing the benefits of Magnetic Resonance Imaging (MRI) in clinical settings is to accelerate acquisition times without significantly degrading image quality. This objective requires a balance between under-sampling the raw k-space measurements for faster acquisitions and gathering sufficient raw information for high-fidelity image reconstruction and analysis tasks. To achieve this balance, we propose to use sequential Bayesian experimental design (BED) to provide an adaptive and task-dependent selection of the most informative measurements. Measurements are sequentially augmented with new samples selected to maximize information gain on a posterior distribution over target images. Selection is performed via a gradient-based optimization of a design parameter that defines a subsampling pattern. In this work, we introduce a new active BED procedure that leverages diffusion-based generative models to handle the high dimensionality of the images and employs stochastic optimization to select among a variety of patterns while meeting the acquisition process constraints and budget. So doing, we show how our setting can optimize, not only standard image reconstruction, but also any associated image analysis task. The versatility and performance of our approach are demonstrated on several MRI acquisitions.

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