IVCVJun 23, 2025

Taming Vision-Language Models for Medical Image Analysis: A Comprehensive Review

arXiv:2506.18378v114 citationsh-index: 4Has Code
Originality Synthesis-oriented
AI Analysis

It provides a systematic overview for researchers to understand and apply VLMs in medical imaging, but it is incremental as it reviews existing work without introducing new methods.

This review addresses the challenge of adapting general-purpose Vision-Language Models (VLMs) to medical image analysis by summarizing recent advances, analyzing current challenges, and recommending future directions, with no specific numerical results reported.

Modern Vision-Language Models (VLMs) exhibit unprecedented capabilities in cross-modal semantic understanding between visual and textual modalities. Given the intrinsic need for multi-modal integration in clinical applications, VLMs have emerged as a promising solution for a wide range of medical image analysis tasks. However, adapting general-purpose VLMs to medical domain poses numerous challenges, such as large domain gaps, complicated pathological variations, and diversity and uniqueness of different tasks. The central purpose of this review is to systematically summarize recent advances in adapting VLMs for medical image analysis, analyzing current challenges, and recommending promising yet urgent directions for further investigations. We begin by introducing core learning strategies for medical VLMs, including pretraining, fine-tuning, and prompt learning. We then categorize five major VLM adaptation strategies for medical image analysis. These strategies are further analyzed across eleven medical imaging tasks to illustrate their current practical implementations. Furthermore, we analyze key challenges that impede the effective adaptation of VLMs to clinical applications and discuss potential directions for future research. We also provide an open-access repository of related literature to facilitate further research, available at https://github.com/haonenglin/Awesome-VLM-for-MIA. It is anticipated that this article can help researchers who are interested in harnessing VLMs in medical image analysis tasks have a better understanding on their capabilities and limitations, as well as current technical barriers, to promote their innovative, robust, and safe application in clinical practice.

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