CVJul 25, 2025

SP-Mamba: Spatial-Perception State Space Model for Unsupervised Medical Anomaly Detection

arXiv:2507.19076v11 citationsh-index: 1Has CodeMM
Originality Incremental advance
AI Analysis

This work addresses the problem of detecting anomalies in medical radiography for healthcare applications, presenting an incremental improvement over existing methods.

The authors tackled unsupervised medical anomaly detection by introducing SP-Mamba, a spatial-perception state space model that leverages the structural regularity of medical images, achieving state-of-the-art performance on three benchmarks.

Radiography imaging protocols target on specific anatomical regions, resulting in highly consistent images with recurrent structural patterns across patients. Recent advances in medical anomaly detection have demonstrated the effectiveness of CNN- and transformer-based approaches. However, CNNs exhibit limitations in capturing long-range dependencies, while transformers suffer from quadratic computational complexity. In contrast, Mamba-based models, leveraging superior long-range modeling, structural feature extraction, and linear computational efficiency, have emerged as a promising alternative. To capitalize on the inherent structural regularity of medical images, this study introduces SP-Mamba, a spatial-perception Mamba framework for unsupervised medical anomaly detection. The window-sliding prototype learning and Circular-Hilbert scanning-based Mamba are introduced to better exploit consistent anatomical patterns and leverage spatial information for medical anomaly detection. Furthermore, we excavate the concentration and contrast characteristics of anomaly maps for improving anomaly detection. Extensive experiments on three diverse medical anomaly detection benchmarks confirm the proposed method's state-of-the-art performance, validating its efficacy and robustness. The code is available at https://github.com/Ray-RuiPan/SP-Mamba.

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