CVOCAug 6, 2025

Towards Globally Predictable k-Space Interpolation: A White-box Transformer Approach

arXiv:2508.04051v1h-index: 6MICCAI
Originality Highly original
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This work addresses the need for reliable and interpretable k-space interpolation in medical imaging, offering a novel approach that enhances both performance and transparency.

The authors tackled the problem of interpolating missing data in k-space for accelerated MRI by proposing GPI-WT, a white-box Transformer framework that leverages global dependencies, resulting in significantly improved accuracy over state-of-the-art methods.

Interpolating missing data in k-space is essential for accelerating imaging. However, existing methods, including convolutional neural network-based deep learning, primarily exploit local predictability while overlooking the inherent global dependencies in k-space. Recently, Transformers have demonstrated remarkable success in natural language processing and image analysis due to their ability to capture long-range dependencies. This inspires the use of Transformers for k-space interpolation to better exploit its global structure. However, their lack of interpretability raises concerns regarding the reliability of interpolated data. To address this limitation, we propose GPI-WT, a white-box Transformer framework based on Globally Predictable Interpolation (GPI) for k-space. Specifically, we formulate GPI from the perspective of annihilation as a novel k-space structured low-rank (SLR) model. The global annihilation filters in the SLR model are treated as learnable parameters, and the subgradients of the SLR model naturally induce a learnable attention mechanism. By unfolding the subgradient-based optimization algorithm of SLR into a cascaded network, we construct the first white-box Transformer specifically designed for accelerated MRI. Experimental results demonstrate that the proposed method significantly outperforms state-of-the-art approaches in k-space interpolation accuracy while providing superior interpretability.

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