Towards Generalizable Learning Models for EEG-Based Identification of Pain Perception
This addresses the challenge of subject-invariant EEG decoding for pain perception, which is incremental as it benchmarks existing methods on a new dataset.
The study tackled the problem of generalizing EEG-based machine learning models for identifying pain perception across individuals, finding that deep learning models, particularly graph-based ones, were more resilient to cross-participant variability than traditional classifiers, with performance evaluated on a dataset of 108 participants.
EEG-based analysis of pain perception, enhanced by machine learning, reveals how the brain encodes pain by identifying neural patterns evoked by noxious stimulation. However, a major challenge that remains is the generalization of machine learning models across individuals, given the high cross-participant variability inherent to EEG signals and the limited focus on direct pain perception identification in current research. In this study, we systematically evaluate the performance of cross-participant generalization of a wide range of models, including traditional classifiers and deep neural classifiers for identifying the sensory modality of thermal pain and aversive auditory stimulation from EEG recordings. Using a novel dataset of EEG recordings from 108 participants, we benchmark model performance under both within- and cross-participant evaluation settings. Our findings show that traditional models suffered the largest drop from within- to cross-participant performance, while deep learning models proved more resilient, underscoring their potential for subject-invariant EEG decoding. Even though performance variability remained high, the strong results of the graph-based model highlight its potential to capture subject-invariant structure in EEG signals. On the other hand, we also share the preprocessed dataset used in this study, providing a standardized benchmark for evaluating future algorithms under the same generalization constraints.