DLAICYAug 18, 2025

The Role of AI in Facilitating Interdisciplinary Collaboration: Evidence from AlphaFold

arXiv:2508.13234v21 citationsh-index: 3
Originality Synthesis-oriented
AI Analysis

This challenges the belief that AI broadly facilitates interdisciplinary collaboration, showing limited efficacy for researchers in fields like structural biology.

The study examined how AI, specifically AlphaFold, affects interdisciplinary collaboration in science, finding it increased structural biology-computer science collaborations by only 0.48% with no significant impact on other disciplines.

The acceleration of artificial intelligence (AI) in science is recognized and many scholars have begun to explore its role in interdisciplinary collaboration. However, the mechanisms and extent of this impact are still unclear. This study, using AlphaFold's impact on structural biologists, examines how AI technologies influence interdisciplinary collaborative patterns. By analyzing 1,247 AlphaFold-related papers and 7,700 authors from Scopus, we employ bibliometric analysis and causal inference to compare interdisciplinary collaboration between AlphaFold adopters and non-adopters. Contrary to the widespread belief that AI facilitates interdisciplinary collaboration, our findings show that AlphaFold increased structural biology-computer science collaborations by just 0.48%, with no measurable effect on other disciplines. Specifically, AI creates interdisciplinary collaboration demands with specific disciplines due to its technical characteristics, but this demand is weakened by technological democratization and other factors. These findings demonstrate that artificial intelligence (AI) alone has limited efficacy in bridging disciplinary divides or fostering meaningful interdisciplinary collaboration.

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