CLAug 19, 2025

EEG-MedRAG: Enhancing EEG-based Clinical Decision-Making via Hierarchical Hypergraph Retrieval-Augmented Generation

arXiv:2508.13735v21 citationsHas Code
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This work addresses the problem of enhancing EEG-based clinical decision support for medical professionals, representing a novel method for a known bottleneck in the field.

The authors tackled the challenge of efficiently retrieving and interpreting large-scale, heterogeneous EEG data for clinical decision-making by proposing EEG-MedRAG, a hypergraph-based retrieval-augmented generation framework, which significantly outperformed TimeRAG and HyperGraphRAG in answer accuracy and retrieval.

With the widespread application of electroencephalography (EEG) in neuroscience and clinical practice, efficiently retrieving and semantically interpreting large-scale, multi-source, heterogeneous EEG data has become a pressing challenge. We propose EEG-MedRAG, a three-layer hypergraph-based retrieval-augmented generation framework that unifies EEG domain knowledge, individual patient cases, and a large-scale repository into a traversable n-ary relational hypergraph, enabling joint semantic-temporal retrieval and causal-chain diagnostic generation. Concurrently, we introduce the first cross-disease, cross-role EEG clinical QA benchmark, spanning seven disorders and five authentic clinical perspectives. This benchmark allows systematic evaluation of disease-agnostic generalization and role-aware contextual understanding. Experiments show that EEG-MedRAG significantly outperforms TimeRAG and HyperGraphRAG in answer accuracy and retrieval, highlighting its strong potential for real-world clinical decision support. Our data and code are publicly available at https://github.com/yi9206413-boop/EEG-MedRAG.

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