LGCLCVAug 21, 2025

Intern-S1: A Scientific Multimodal Foundation Model

arXiv:2508.15763v232 citationsh-index: 32Has Code
Originality Incremental advance
AI Analysis

This work addresses the problem of limited open-source foundation models for high-value scientific fields, offering a specialized generalist model to advance scientific research and AGI, though it is incremental as it builds on existing multimodal and MoE approaches.

The paper tackles the gap between open-source and closed-source foundation models in scientific domains by introducing Intern-S1, a multimodal Mixture-of-Experts model with 28 billion activated parameters, which achieves competitive performance on general reasoning tasks and surpasses closed-source state-of-the-art models in specific scientific tasks like molecular synthesis planning and reaction condition prediction.

In recent years, a plethora of open-source foundation models have emerged, achieving remarkable progress in some widely attended fields, with performance being quite close to that of closed-source models. However, in high-value but more challenging scientific professional fields, either the fields still rely on expert models, or the progress of general foundation models lags significantly compared to those in popular areas, far from sufficient for transforming scientific research and leaving substantial gap between open-source models and closed-source models in these scientific domains. To mitigate this gap and explore a step further toward Artificial General Intelligence (AGI), we introduce Intern-S1, a specialized generalist equipped with general understanding and reasoning capabilities with expertise to analyze multiple science modal data. Intern-S1 is a multimodal Mixture-of-Experts (MoE) model with 28 billion activated parameters and 241 billion total parameters, continually pre-trained on 5T tokens, including over 2.5T tokens from scientific domains. In the post-training stage, Intern-S1 undergoes offline and then online reinforcement learning (RL) in InternBootCamp, where we propose Mixture-of-Rewards (MoR) to synergize the RL training on more than 1000 tasks simultaneously. Through integrated innovations in algorithms, data, and training systems, Intern-S1 achieved top-tier performance in online RL training. On comprehensive evaluation benchmarks, Intern-S1 demonstrates competitive performance on general reasoning tasks among open-source models and significantly outperforms open-source models in scientific domains, surpassing closed-source state-of-the-art models in professional tasks, such as molecular synthesis planning, reaction condition prediction, predicting thermodynamic stabilities for crystals. Our models are available at https://huggingface.co/internlm/Intern-S1.

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