CVAIAug 28, 2025

Safer Skin Lesion Classification with Global Class Activation Probability Map Evaluation and SafeML

arXiv:2508.20776v1h-index: 7IMBSA
Originality Incremental advance
AI Analysis

This work addresses the need for trustworthy and explainable AI in medical diagnostics, particularly for skin lesion classification, though it appears incremental in improving existing explainability methods.

The paper tackled the problem of distrust in AI models for skin lesion classification by proposing a method to improve explainability and reliability, achieving enhanced diagnostic safety through visualization and false diagnosis detection.

Recent advancements in skin lesion classification models have significantly improved accuracy, with some models even surpassing dermatologists' diagnostic performance. However, in medical practice, distrust in AI models remains a challenge. Beyond high accuracy, trustworthy, explainable diagnoses are essential. Existing explainability methods have reliability issues, with LIME-based methods suffering from inconsistency, while CAM-based methods failing to consider all classes. To address these limitations, we propose Global Class Activation Probabilistic Map Evaluation, a method that analyses all classes' activation probability maps probabilistically and at a pixel level. By visualizing the diagnostic process in a unified manner, it helps reduce the risk of misdiagnosis. Furthermore, the application of SafeML enhances the detection of false diagnoses and issues warnings to doctors and patients as needed, improving diagnostic reliability and ultimately patient safety. We evaluated our method using the ISIC datasets with MobileNetV2 and Vision Transformers.

Foundations

The foundational work for this paper's niche, ranked by how specifically the neighbourhood builds on it — not by global fame.

Your Notes