Mamba-Based Modality Disentanglement Network for Multi-Contrast MRI Reconstruction
This work solves faster and more accurate MRI scans for clinical diagnosis, though it appears incremental as it builds on existing multi-contrast techniques.
The paper tackled accelerated MRI reconstruction by addressing aliasing artifacts and modality contamination in multi-contrast fusion, resulting in MambaMDN outperforming existing methods with significant improvements.
Magnetic resonance imaging (MRI) is a cornerstone of modern clinical diagnosis, offering unparalleled soft-tissue contrast without ionizing radiation. However, prolonged scan times remain a major barrier to patient throughput and comfort. Existing accelerated MRI techniques often struggle with two key challenges: (1) failure to effectively utilize inherent K-space prior information, leading to persistent aliasing artifacts from zero-filled inputs; and (2) contamination of target reconstruction quality by irrelevant information when employing multi-contrast fusion strategies. To overcome these challenges, we present MambaMDN, a dual-domain framework for multi-contrast MRI reconstruction. Our approach first employs fully-sampled reference K-space data to complete the undersampled target data, generating structurally aligned but modality-mixed inputs. Subsequently, we develop a Mamba-based modality disentanglement network to extract and remove reference-specific features from the mixed representation. Furthermore, we introduce an iterative refinement mechanism to progressively enhance reconstruction accuracy through repeated feature purification. Extensive experiments demonstrate that MambaMDN can significantly outperform existing multi-contrast reconstruction methods.