CLJan 12

A Human-Centric Pipeline for Aligning Large Language Models with Chinese Medical Ethics

arXiv:2601.07954v1
Originality Incremental advance
AI Analysis

This addresses the challenge of ensuring LLMs adhere to nuanced medical ethics in Chinese healthcare, though it appears incremental as it adapts existing alignment methods to a specific domain.

The researchers tackled the problem of aligning large language models with Chinese medical ethics by creating MedES, a dynamic benchmark from 260 authoritative sources, and a guardian-in-the-loop framework with an automated evaluator achieving over 97% accuracy. Their aligned 7B-parameter model outperformed larger baselines on core ethical tasks in the Chinese medical context.

Recent advances in large language models have enabled their application to a range of healthcare tasks. However, aligning LLMs with the nuanced demands of medical ethics, especially under complex real world scenarios, remains underexplored. In this work, we present MedES, a dynamic, scenario-centric benchmark specifically constructed from 260 authoritative Chinese medical, ethical, and legal sources to reflect the challenges in clinical decision-making. To facilitate model alignment, we introduce a guardian-in-the-loop framework that leverages a dedicated automated evaluator (trained on expert-labeled data and achieving over 97% accuracy within our domain) to generate targeted prompts and provide structured ethical feedback. Using this pipeline, we align a 7B-parameter LLM through supervised fine-tuning and domain-specific preference optimization. Experimental results, conducted entirely within the Chinese medical ethics context, demonstrate that our aligned model outperforms notably larger baselines on core ethical tasks, with observed improvements in both quality and composite evaluation metrics. Our work offers a practical and adaptable framework for aligning LLMs with medical ethics in the Chinese healthcare domain, and suggests that similar alignment pipelines may be instantiated in other legal and cultural environments through modular replacement of the underlying normative corpus.

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