MosaicMRI: A Diverse Dataset and Benchmark for Raw Musculoskeletal MRI

arXiv:2604.1176258.1h-index: 7Has Code
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This dataset and benchmark address the lack of diverse raw MSK MRI data for training and evaluating deep learning models, enabling studies on cross-anatomy generalization and scaling behavior.

MosaicMRI introduces the largest open-source raw musculoskeletal MRI dataset (2,671 volumes, 80,156 slices) with diverse anatomies, orientations, and contrasts. Using VarNet for accelerated reconstruction, they show that models trained on combined anatomies outperform anatomy-specific ones in low-sample regimes, and identify cross-anatomy generalization patterns.

Deep learning underpins a wide range of applications in MRI, including reconstruction, artifact removal, and segmentation. However, progress has been driven largely by public datasets focused on brain and knee imaging, shaping how models are trained and evaluated. As a result, careful studies of the reliability of these models across diverse anatomical settings remain limited. In this work, we introduce MosaicMRI, a large and diverse collection of fully sampled raw musculoskeletal (MSK) MR measurements designed for training and evaluating machine-learning-based methods. MosaicMRI is the largest open-source raw MSK MRI dataset to date, comprising 2,671 volumes and 80,156 slices. The dataset offers substantial diversity in volume orientation (e.g., axial, sagittal), imaging contrasts (e.g., PD, T1, T2), anatomies (e.g., spine, knee, hip, ankle, and others), and numbers of acquisition coils. Using VarNet as a baseline for accelerated reconstruction task, we perform a comprehensive set of experiments to study scaling behavior with respect to both model capacity and dataset size. Interestingly, models trained on the combined anatomies significantly outperform anatomy-specific models in low-sample regimes, highlighting the benefits of anatomical diversity and the presence of exploitable cross-anatomical correlations. We further evaluate robustness and cross-anatomy generalization by training models on one anatomy (e.g., spine) and testing them on another (e.g., knee). Notably, we identify groups of body parts (e.g., foot and elbow) that generalize well with each other, and highlight that performance under domain shifts depends on both training set size, anatomy, and protocol-specific factors.

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