Yiqun Chen

Yiqun Chen, Qiang Chen, Peize Sun et al.

We present a conceptually simple, efficient, and general framework for localization problems in DETR-like models. We add plugins to well-trained models instead of inefficiently designing new models and training them from scratch. The method, called RefineBox, refines the outputs of DETR-like detectors by lightweight refinement networks. RefineBox is easy to implement and train as it only leverages the features and predicted boxes from the well-trained detection models. Our method is also efficient as we freeze the trained detectors during training. In addition, we can easily generalize RefineBox to various trained detection models without any modification. We conduct experiments on COCO and LVIS $1.0$. Experimental results indicate the effectiveness of our RefineBox for DETR and its representative variants (Figure 1). For example, the performance gains for DETR, Conditinal-DETR, DAB-DETR, and DN-DETR are 2.4 AP, 2.5 AP, 1.9 AP, and 1.6 AP, respectively. We hope our work will bring the attention of the detection community to the localization bottleneck of current DETR-like models and highlight the potential of the RefineBox framework. Code and models will be publicly available at: \href{https://github.com/YiqunChen1999/RefineBox}{https://github.com/YiqunChen1999/RefineBox}.

Yiqun Chen, Qiang Chen, Qinghao Hu et al.

Fully convolutional detectors discard the one-to-many assignment and adopt a one-to-one assigning strategy to achieve end-to-end detection but suffer from the slow convergence issue. In this paper, we revisit these two assignment methods and find that bringing one-to-many assignment back to end-to-end fully convolutional detectors helps with model convergence. Based on this observation, we propose {\em \textbf{D}ual \textbf{A}ssignment} for end-to-end fully convolutional de\textbf{TE}ction (DATE). Our method constructs two branches with one-to-many and one-to-one assignment during training and speeds up the convergence of the one-to-one assignment branch by providing more supervision signals. DATE only uses the branch with the one-to-one matching strategy for model inference, which doesn't bring inference overhead. Experimental results show that Dual Assignment gives nontrivial improvements and speeds up model convergence upon OneNet and DeFCN. Code: https://github.com/YiqunChen1999/date.

Haolin Pan, Yong Guo, Qinyi Deng et al.

Self-supervised learning (SSL) has achieved remarkable performance in pretraining the models that can be further used in downstream tasks via fine-tuning. However, these self-supervised models may not capture meaningful semantic information since the images belonging to the same class are always regarded as negative pairs in the contrastive loss. Consequently, the images of the same class are often located far away from each other in learned feature space, which would inevitably hamper the fine-tuning process. To address this issue, we seek to provide a better initialization for the self-supervised models by enhancing the semantic information. To this end, we propose a Contrastive Initialization (COIN) method that breaks the standard fine-tuning pipeline by introducing an extra initialization stage before fine-tuning. Extensive experiments show that, with the enriched semantics, our COIN significantly outperforms existing methods without introducing extra training cost and sets new state-of-the-arts on multiple downstream tasks.

Hangyu Mao, Rui Zhao, Hao Chen et al.

Designing better deep networks and better reinforcement learning (RL) algorithms are both important for deep RL. This work focuses on the former. Previous methods build the network with several modules like CNN, LSTM and Attention. Recent methods combine the Transformer with these modules for better performance. However, it requires tedious optimization skills to train a network composed of mixed modules, making these methods inconvenient to be used in practice. In this paper, we propose to design \emph{pure Transformer-based networks} for deep RL, aiming at providing off-the-shelf backbones for both the online and offline settings. Specifically, the Transformer in Transformer (TIT) backbone is proposed, which cascades two Transformers in a very natural way: the inner one is used to process a single observation, while the outer one is responsible for processing the observation history; combining both is expected to extract spatial-temporal representations for good decision-making. Experiments show that TIT can achieve satisfactory performance in different settings consistently.

Yiqun Chen, Lingyong Yan, Zixuan Yang et al.

Agentic search has emerged as a promising paradigm for complex information seeking by enabling Large Language Models (LLMs) to interleave reasoning with tool use. However, prevailing systems rely on monolithic agents that suffer from structural bottlenecks, including unconstrained reasoning outputs that inflate trajectories, sparse outcome-level rewards that complicate credit assignment, and stochastic search noise that destabilizes learning. To address these challenges, we propose \textbf{M-ASK} (Multi-Agent Search and Knowledge), a framework that explicitly decouples agentic search into two complementary roles: Search Behavior Agents, which plan and execute search actions, and Knowledge Management Agents, which aggregate, filter, and maintain a compact internal context. This decomposition allows each agent to focus on a well-defined subtask and reduces interference between search and context construction. Furthermore, to enable stable coordination, M-ASK employs turn-level rewards to provide granular supervision for both search decisions and knowledge updates. Experiments on multi-hop QA benchmarks demonstrate that M-ASK outperforms strong baselines, achieving not only superior answer accuracy but also significantly more stable training dynamics.\footnote{The source code for M-ASK is available at https://github.com/chenyiqun/M-ASK.}

Yiqun Chen, Hangyu Mao, Jiaxin Mao et al.

Centralized Training with Decentralized Execution (CTDE) has emerged as a widely adopted paradigm in multi-agent reinforcement learning, emphasizing the utilization of global information for learning an enhanced joint $Q$-function or centralized critic. In contrast, our investigation delves into harnessing global information to directly enhance individual $Q$-functions or individual actors. Notably, we discover that applying identical global information universally across all agents proves insufficient for optimal performance. Consequently, we advocate for the customization of global information tailored to each agent, creating agent-personalized global information to bolster overall performance. Furthermore, we introduce a novel paradigm named Personalized Training with Distilled Execution (PTDE), wherein agent-personalized global information is distilled into the agent's local information. This distilled information is then utilized during decentralized execution, resulting in minimal performance degradation. PTDE can be seamlessly integrated with state-of-the-art algorithms, leading to notable performance enhancements across diverse benchmarks, including the SMAC benchmark, Google Research Football (GRF) benchmark, and Learning to Rank (LTR) task.

Zixuan Yang, Yiqun Chen, Wei Yang et al.

Reinforcement learning in open-ended long-form generation is challenging because reliable reference answers and automatic metrics are often unavailable. Existing rubric-based methods typically rely on pointwise LLM-as-a-judge scoring, but absolute scores are difficult to calibrate across complex responses, may provide weak discrimination among same-query rollouts, and can become saturated during optimization. We propose Tournament-GRPO, a group-wise reward framework that converts rubric-guided LLM judgments into relative rewards through repeated multi-round tournaments among same-query rollouts. Tournament-GRPO compares candidates within groups, accumulates tournament outcomes, and normalizes them into group-wise rewards for GRPO training. Experiments on Deep Research Bench show that Tournament-GRPO consistently outperforms existing reward-design baselines, achieving a 4.52-point overall-score improvement over the strongest baseline. Further analyses show that tournament rewards provide a favorable effectiveness--efficiency trade-off and that tournament design affects training dynamics. These results suggest that rubric-guided tournament comparison provides an effective reward signal for reinforcement learning in open-ended long-form generation.

Yiqun Chen, Wei Yang, Erhan Zhang et al.

LLM-based multi-agent systems decompose complex tasks into interacting roles, but most remain manually orchestrated by prompts, tools, and control rules, while agents are rarely optimized through a unified reinforcement learning interface. Existing RL post-training frameworks mainly target single-policy optimization and lack abstractions for user-defined multi-agent workflows, structured interaction, role-specific credit assignment, and configurable parameter sharing. We present UnityMAS-O, a general RL optimization framework for LLM-based multi-agent systems. UnityMAS-O treats the complete workflow as the optimization unit, rather than a single response or policy trajectory. It represents workflows through four first-class objects: logical agent roles, graph trajectories, user-defined rewards, and agent--model mappings. This decouples logical agents from physical model parameters, supporting full sharing, full separation, and partial sharing, with rewards assigned at role, turn, and trajectory levels. UnityMAS-O extends verl with a Ray-based star-topology runtime. A central controller executes workflows, invokes tools, records structured trajectories, and assembles rewards; model-local worker groups handle rollout, buffering, advantage computation, and distributed PPO-style updates. Users can define agents, workflows, model mappings, and rewards without rewriting the optimization infrastructure. We instantiate UnityMAS-O on retrieval-augmented QA, iterative agentic search, and reflective code generation. Across Natural Questions, HotpotQA, and held-out code tasks, multi-agent RL improves manually specified workflows after optimization, with especially large gains for smaller models and strict code all-passed metrics. These results show that UnityMAS-O can serve as a reusable substrate for converting diverse LLM-based multi-agent workflows into trainable multi-agent RL systems.

Jinyuan Feng, Xin Yu, Yiqun Chen et al.

The iterative denoising paradigm of Diffusion Large Language Models (DLMs) endows them with a distinct advantage in global context modeling. However, current decoding strategies fail to leverage this capability, typically exhibiting a local preference that overlooks the heterogeneous information density within the context, ultimately degrading generation quality. To address this limitation, we systematically investigate high-information-density (HD) tokens and present two key findings: (1) explicitly conditioning on HD tokens substantially improves output quality; and (2) HD tokens exhibit an early-decoding tendency, converging earlier than surrounding tokens. Motivated by these findings, we propose Focus on the Core \textbf{(FoCore)}, a training-free decoding strategy that utilizes HD tokens in a self-contrast manner, wherein HD tokens are temporarily remasked as negative samples, to guide generation. We further introduce FoCore\_Accelerate \textbf{(FoCore\_A)}, an efficient variant that, upon detecting HD token convergence, performs parallel decoding over stable candidates within a local context window, substantially accelerating generation. Extensive experiments on math, code and logical reasoning benchmarks demonstrate that FoCore consistently improves generation quality and efficiency across both LLaDA and Dream backbones. For instance, on HumanEval, FoCore improves pass@1 from 39.02 to 42.68 over standard Classifier-Free Guidance, while FoCore-A reduces the number of decoding steps by 2.07x and per-sample latency from 20.76s to 8.64s (-58.4\%).

Hangyu Mao, Rui Zhao, Ziyue Li et al.

Designing better deep networks and better reinforcement learning (RL) algorithms are both important for deep RL. This work studies the former. Specifically, the Perception and Decision-making Interleaving Transformer (PDiT) network is proposed, which cascades two Transformers in a very natural way: the perceiving one focuses on \emph{the environmental perception} by processing the observation at the patch level, whereas the deciding one pays attention to \emph{the decision-making} by conditioning on the history of the desired returns, the perceiver's outputs, and the actions. Such a network design is generally applicable to a lot of deep RL settings, e.g., both the online and offline RL algorithms under environments with either image observations, proprioception observations, or hybrid image-language observations. Extensive experiments show that PDiT can not only achieve superior performance than strong baselines in different settings but also extract explainable feature representations. Our code is available at \url{https://github.com/maohangyu/PDiT}.

Jasmin Han, Janardan Devkota, Joseph Waring et al.

Perceived message effectiveness (PME) by potential intervention end-users is important for selecting and optimizing personalized smoking cessation intervention messages for mobile health (mHealth) platform delivery. This study evaluates whether large language models (LLMs) can accurately predict PME for smoking cessation messages. We evaluated multiple models for predicting PME across three domains: content quality, coping support, and quitting support. The dataset comprised 3010 message ratings (5-point Likert scale) from 301 young adult smokers. We compared (1) supervised learning models trained on labeled data, (2) zero and few-shot LLMs prompted without task-specific fine-tuning, and (3) LLM-based digital twins that incorporate individual characteristics and prior PME histories to generate personalized predictions. Model performance was assessed on three held-out messages per participant using accuracy, Cohen's kappa, and F1. LLM-based digital twins outperformed zero and few-shot LLMs (12 percentage points on average) and supervised baselines (13 percentage points), achieving accuracies of 0.49 (content), 0.45 (coping), and 0.49 (quitting), with directional accuracies of 0.75, 0.66, and 0.70 on a simplified 3-point scale. Digital twin predictions showed greater dispersion across rating categories, indicating improved sensitivity to individual differences. Integrating personal profiles with LLMs captures person-specific differences in PME and outperforms supervised and zero and few-shot approaches. Improved PME prediction may enable more tailored intervention content in mHealth. LLM-based digital twins show potential for supporting personalization of mobile smoking cessation and other health behavior change interventions.

Qi Liu, Haozhe Duan, Yiqun Chen et al.

Utilizing large language models (LLMs) for document reranking has been a popular and promising research direction in recent years, many studies are dedicated to improving the performance and efficiency of using LLMs for reranking. Besides, it can also be applied in many real-world applications, such as search engines or retrieval-augmented generation. In response to the growing demand for research and application in practice, we introduce a unified framework, \textbf{LLM4Ranking}, which enables users to adopt different ranking methods using open-source or closed-source API-based LLMs. Our framework provides a simple and extensible interface for document reranking with LLMs, as well as easy-to-use evaluation and fine-tuning scripts for this task. We conducted experiments based on this framework and evaluated various models and methods on several widely used datasets, providing reproducibility results on utilizing LLMs for document reranking. Our code is publicly available at https://github.com/liuqi6777/llm4ranking.

Yiqun Chen, Jiaxin Mao, Yi Zhang et al.

Search result diversification (SRD), which aims to ensure that documents in a ranking list cover a broad range of subtopics, is a significant and widely studied problem in Information Retrieval and Web Search. Existing methods primarily utilize a paradigm of "greedy selection", i.e., selecting one document with the highest diversity score at a time or optimize an approximation of the objective function. These approaches tend to be inefficient and are easily trapped in a suboptimal state. To address these challenges, we introduce Multi-Agent reinforcement learning (MARL) for search result DIVersity, which called MA4DIV. In this approach, each document is an agent and the search result diversification is modeled as a cooperative task among multiple agents. By modeling the SRD ranking problem as a cooperative MARL problem, this approach allows for directly optimizing the diversity metrics, such as $α$-NDCG, while achieving high training efficiency. We conducted experiments on public TREC datasets and a larger scale dataset in the industrial setting. The experiemnts show that MA4DIV achieves substantial improvements in both effectiveness and efficiency than existing baselines, especially on the industrial dataset. The code of MA4DIV can be seen on https://github.com/chenyiqun/MA4DIV.

Yiqun Chen, Jinyuan Feng, Wei Yang et al.

The inference overhead induced by redundant reasoning undermines the interactive experience and severely bottlenecks the deployment of Large Reasoning Models. Existing reinforcement learning (RL)-based solutions tackle this problem by coupling a length penalty with outcome-based rewards. This simplistic reward weighting struggles to reconcile brevity with accuracy, as enforcing brevity may compromise critical reasoning logic. In this work, we address this limitation by proposing a multi-agent RL framework that selectively penalizes redundant chunks, while preserving essential reasoning logic. Our framework, Self-Compression via MARL (SCMA), instantiates redundancy detection and evaluation through two specialized agents: \textbf{a Segmentation Agent} for decomposing the reasoning process into logical chunks, and \textbf{a Scoring Agent} for quantifying the significance of each chunk. The Segmentation and Scoring agents collaboratively define an importance-weighted length penalty during training, incentivizing \textbf{a Reasoning Agent} to prioritize essential logic without introducing inference overhead during deployment. Empirical evaluations across model scales demonstrate that SCMA reduces response length by 11.1\% to 39.0\% while boosting accuracy by 4.33\% to 10.02\%. Furthermore, ablation studies and qualitative analysis validate that the synergistic optimization within the MARL framework fosters emergent behaviors, yielding more powerful LRMs compared to vanilla RL paradigms.

Yiqun Chen, Erhan Zhang, Lingyong Yan et al. · baidu

In question-answering (QA) systems, Retrieval-Augmented Generation (RAG) has become pivotal in enhancing response accuracy and reducing hallucination issues. The architecture of RAG systems varies significantly, encompassing single-round RAG, iterative RAG, and reasoning RAG, each tailored to address different types of queries. Due to the varying complexity of real-world queries, a fixed RAG pipeline often struggles to balance performance and cost efficiency across different queries. To address this challenge, we propose an adaptive RAG framework called MAO-ARAG, which leverages multi-agent orchestration. Our adaptive RAG is conceived as a multi-turn framework. Specifically, we define multiple executor agents, representing typical RAG modules such as query reformulation agents, document selection agent, and generation agents. A planner agent intelligently selects and integrates the appropriate agents from these executors into a suitable workflow tailored for each query, striving for high-quality answers while maintaining reasonable costs. During each turn, the planner agent is trained using reinforcement learning, guided by an outcome-based reward (F1 score) and a cost-based penalty, continuously improving answer quality while keeping costs within a reasonable range. Experiments conducted on multiple QA datasets demonstrate that our approach, which dynamically plans workflows for each query, not only achieves high answer quality but also maintains both cost and latency within acceptable limits.The code of MAO-ARAG is on https://github.com/chenyiqun/Agentic-RAG.

Wei Yang, Rui Zhong, Yiqun Chen et al.

Multimodal recommendation aims to integrate collaborative signals with heterogeneous content such as visual and textual information, but remains challenged by modality-specific noise, semantic inconsistency, and unstable propagation over user-item graphs. These issues are often exacerbated by naive fusion or shallow modeling strategies, leading to degraded generalization and poor robustness. While recent work has explored the frequency domain as a lens to separate stable from noisy signals, most methods rely on static filtering or reweighting, lacking the ability to reason over spectral structure or adapt to modality-specific reliability. To address these challenges, we propose a Structured Spectral Reasoning (SSR) framework for frequency-aware multimodal recommendation. Our method follows a four-stage pipeline: (i) Decompose graph-based multimodal signals into spectral bands via graph-guided transformations to isolate semantic granularity; (ii) Modulate band-level reliability with spectral band masking, a training-time masking with a prediction-consistency objective that suppresses brittle frequency components; (iii) Fuse complementary frequency cues using hyperspectral reasoning with low-rank cross-band interaction; and (iv) Align modality-specific spectral features via contrastive regularization to promote semantic and structural consistency. Experiments on three real-world benchmarks show consistent gains over strong baselines, particularly under sparse and cold-start settings. Additional analyses indicate that structured spectral modeling improves robustness and provides clearer diagnostics of how different bands contribute to performance.

Yiqun Chen, Erhan Zhang, Tianyi Hu et al.

The evolution of Retrieval-Augmented Generation (RAG) has shifted from static retrieval pipelines to dynamic, agentic workflows where a central planner orchestrates multi-turn reasoning. However, existing paradigms face a critical dichotomy: they either optimize modules jointly within rigid, fixed-graph architectures, or empower dynamic planning while treating executors as frozen, black-box tools. We identify that this \textit{decoupled optimization} creates a ``strategic-operational mismatch,'' where sophisticated planning strategies fail to materialize due to unadapted local executors, often leading to negative performance gains despite increased system complexity. In this paper, we propose \textbf{JADE} (\textbf{J}oint \textbf{A}gentic \textbf{D}ynamic \textbf{E}xecution), a unified framework for the joint optimization of planning and execution within dynamic, multi-turn workflows. By modeling the system as a cooperative multi-agent team unified under a single shared backbone, JADE enables end-to-end learning driven by outcome-based rewards. This approach facilitates \textit{co-adaptation}: the planner learns to operate within the capability boundaries of the executors, while the executors evolve to align with high-level strategic intent. Empirical results demonstrate that JADE transforms disjoint modules into a synergistic system, yielding remarkable performance improvements via joint optimization and enabling a flexible balance between efficiency and effectiveness through dynamic workflow orchestration.

Yiqun Chen, Qi Liu, Yi Zhang et al.

Large Language Models (LLMs) are increasingly employed in zero-shot documents ranking, yielding commendable results. However, several significant challenges still persist in LLMs for ranking: (1) LLMs are constrained by limited input length, precluding them from processing a large number of documents simultaneously; (2) The output document sequence is influenced by the input order of documents, resulting in inconsistent ranking outcomes; (3) Achieving a balance between cost and ranking performance is challenging. To tackle these issues, we introduce a novel documents ranking method called TourRank, which is inspired by the sport tournaments, such as FIFA World Cup. Specifically, we 1) overcome the limitation in input length and reduce the ranking latency by incorporating a multi-stage grouping strategy similar to the parallel group stage of sport tournaments; 2) improve the ranking performance and robustness to input orders by using a points system to ensemble multiple ranking results. We test TourRank with different LLMs on the TREC DL datasets and the BEIR benchmark. The experimental results demonstrate that TourRank delivers state-of-the-art performance at a modest cost. The code of TourRank can be seen on https://github.com/chenyiqun/TourRank.

Erhan Zhang, Yiqun Chen, Zechun Niu et al.

In agentic search, large language models (LLMs) are trained to perform multi-turn retrieval and reasoning for complex tasks such as multi-hop question answering (QA). However, current search-based Reinforcement Learning (RL) methods suffer from two core limitations: expensive long-horizon rollouts are under-utilized during training, and supervision is typically available only at the final answer, resulting in severe reward sparsity. We present Prefix-based Rollout reuse for Agentic search with Intermediate Step rEwards (PRAISE), a framework for improving both data efficiency and credit assignment in agentic search training. Given a complete search trajectory, PRAISE extracts prefix states at different search turns, elicits intermediate answers from them, and uses these prefixes both to construct additional training trajectories and to derive step-level rewards from performance differences across prefixes. Our method uses a single shared model for both search policy learning and prefix answer evaluation, enabling joint optimization without extra human annotations or a separate reward model. Experiments on multi-hop QA benchmarks show that PRAISE consistently improves performance over strong baselines.

Weixin Liang, Nazneen Rajani, Xinyu Yang et al. · salesforce, stanford

The rapid proliferation of AI models has underscored the importance of thorough documentation, as it enables users to understand, trust, and effectively utilize these models in various applications. Although developers are encouraged to produce model cards, it's not clear how much information or what information these cards contain. In this study, we conduct a comprehensive analysis of 32,111 AI model documentations on Hugging Face, a leading platform for distributing and deploying AI models. Our investigation sheds light on the prevailing model card documentation practices. Most of the AI models with substantial downloads provide model cards, though the cards have uneven informativeness. We find that sections addressing environmental impact, limitations, and evaluation exhibit the lowest filled-out rates, while the training section is the most consistently filled-out. We analyze the content of each section to characterize practitioners' priorities. Interestingly, there are substantial discussions of data, sometimes with equal or even greater emphasis than the model itself. To evaluate the impact of model cards, we conducted an intervention study by adding detailed model cards to 42 popular models which had no or sparse model cards previously. We find that adding model cards is moderately correlated with an increase weekly download rates. Our study opens up a new perspective for analyzing community norms and practices for model documentation through large-scale data science and linguistics analysis.

Yiqun Chen, Lingyong Yan, Weiwei Sun et al.

Retrieval-augmented generation (RAG) is widely utilized to incorporate external knowledge into large language models, thereby enhancing factuality and reducing hallucinations in question-answering (QA) tasks. A standard RAG pipeline consists of several components, such as query rewriting, document retrieval, document filtering, and answer generation. However, these components are typically optimized separately through supervised fine-tuning, which can lead to misalignments between the objectives of individual components and the overarching aim of generating accurate answers. Although recent efforts have explored using reinforcement learning (RL) to optimize specific RAG components, these approaches often focus on simple pipelines with only two components or do not adequately address the complex interdependencies and collaborative interactions among the modules. To overcome these limitations, we propose treating the complex RAG pipeline with multiple components as a multi-agent cooperative task, in which each component can be regarded as an RL agent. Specifically, we present MMOA-RAG, Multi-Module joint Optimization Algorithm for RAG, which employs multi-agent reinforcement learning to harmonize all agents' goals toward a unified reward, such as the F1 score of the final answer. Experiments conducted on various QA benchmarks demonstrate that MMOA-RAG effectively boost the overall performance of the pipeline and outperforms existing baselines. Furthermore, comprehensive ablation studies validate the contributions of individual components and demonstrate MMOA-RAG can be adapted to different RAG pipelines and benchmarks.

Yuchen Li, Hengyi Cai, Rui Kong et al.

In this paper, we introduce the AI Search Paradigm, a comprehensive blueprint for next-generation search systems capable of emulating human information processing and decision-making. The paradigm employs a modular architecture of four LLM-powered agents (Master, Planner, Executor and Writer) that dynamically adapt to the full spectrum of information needs, from simple factual queries to complex multi-stage reasoning tasks. These agents collaborate dynamically through coordinated workflows to evaluate query complexity, decompose problems into executable plans, and orchestrate tool usage, task execution, and content synthesis. We systematically present key methodologies for realizing this paradigm, including task planning and tool integration, execution strategies, aligned and robust retrieval-augmented generation, and efficient LLM inference, spanning both algorithmic techniques and infrastructure-level optimizations. By providing an in-depth guide to these foundational components, this work aims to inform the development of trustworthy, adaptive, and scalable AI search systems.

Can Wang, Hongyu Zhao, Yiqun Chen

Causal inference is central to scientific discovery, yet choosing appropriate methods remains challenging because of the complexity of both statistical methodology and real-world data. Inspired by the success of artificial intelligence in accelerating scientific discovery, we introduce InferenceEvolve, an evolutionary framework that uses large language models to discover and iteratively refine causal methods. Across widely used benchmarks, InferenceEvolve yields estimators that consistently outperform established baselines: against 58 human submissions in a recent community competition, our best evolved estimator lay on the Pareto frontier across two evaluation metrics. We also developed robust proxy objectives for settings without semi-synthetic outcomes, with competitive results. Analysis of the evolutionary trajectories shows that agents progressively discover sophisticated strategies tailored to unrevealed data-generating mechanisms. These findings suggest that language-model-guided evolution can optimize structured scientific programs such as causal inference, even when outcomes are only partially observed.

Can Wang, Yiqun Chen

Large Language Models (LLMs) have demonstrated substantial progress in biomedical and clinical applications, motivating rigorous evaluation of their ability to answer nuanced, evidence-based questions. We curate a multi-source benchmark drawing from Cochrane systematic reviews and clinical guidelines, including structured recommendations from the American Heart Association and narrative guidance used by insurers. Using GPT-4o-mini and GPT-5, we observe consistent performance patterns across sources and clinical domains: accuracy is highest on structured guideline recommendations (90%) and lower on narrative guideline and systematic review questions (60--70%). We also find a strong correlation between accuracy and the citation count of the underlying systematic reviews, where each doubling of citations is associated with roughly a 30% increase in the odds of a correct answer. Models show moderate ability to reason about evidence quality when contextual information is supplied. When we incorporate retrieval-augmented prompting, providing the gold-source abstract raises accuracy on previously incorrect items to 0.79; providing top 3 PubMed abstracts (ranked by semantic relevance) improves accuracy to 0.23, while random abstracts reduce accuracy (0.10, within temperature variation). These effects are mirrored in GPT-4o-mini, underscoring that source clarity and targeted retrieval -- not just model size -- drive performance. Overall, our results highlight both the promise and current limitations of LLMs for evidence-based clinical question answering. Retrieval-augmented prompting emerges as a useful strategy to improve factual accuracy and alignment with source evidence, while stratified evaluation by specialty and question type remains essential to understand current knowledge access and to contextualize model performance.

Zhengliang Shi, Yiqun Chen, Haitao Li et al.

Large language models (LLMs) have rapidly evolved from text generators into powerful problem solvers. Yet, many open tasks demand critical thinking, multi-source, and verifiable outputs, which are beyond single-shot prompting or standard retrieval-augmented generation. Recently, numerous studies have explored Deep Research (DR), which aims to combine the reasoning capabilities of LLMs with external tools, such as search engines, thereby empowering LLMs to act as research agents capable of completing complex, open-ended tasks. This survey presents a comprehensive and systematic overview of deep research systems, including a clear roadmap, foundational components, practical implementation techniques, important challenges, and future directions. Specifically, our main contributions are as follows: (i) we formalize a three-stage roadmap and distinguish deep research from related paradigms; (ii) we introduce four key components: query planning, information acquisition, memory management, and answer generation, each paired with fine-grained sub-taxonomies; (iii) we summarize optimization techniques, including prompting, supervised fine-tuning, and agentic reinforcement learning; and (iv) we consolidate evaluation criteria and open challenges, aiming to guide and facilitate future development. As the field of deep research continues to evolve rapidly, we are committed to continuously updating this survey to reflect the latest progress in this area.