Ping Zhang

Zhixin Wang, Jiaming Xu, Tianyi Zhou et al.

Effectively scaling Reinforcement Learning (RL) is crucial for enhancing the reasoning and alignment of Large Language Models. The massive data and complex execution flows inherent in these tasks require a distributed architecture capable of efficient scaling. However, to simplify programming and dependency management, mainstream frameworks often rely on a centralized architecture where a single node dispatches both control and data. This inherent coupling creates significant communication bottlenecks, severely limiting system scalability and efficiency. We present DISTFLOW, a novel, fully distributed RL framework that adopts a multi-controller paradigm. By decoupling data transmission from control dispatch, DISTFLOW establishes a parallelism-aware, decentralized Data Coordinator that leverages local caching, load balancing, and asynchronous double buffer to minimize communication overhead and mitigate straggler effects. For control logic, it introduces a task scheduler built upon Directed Acyclic Graph (DAG) that facilitates fine-grained, independent execution. Experimental results demonstrate that DISTFLOW achieves near-linear scalability up to 512 GPUs and delivers up to a 2.63x throughput improvement over state-of-the-art (SOTA) frameworks. The source code is available at: https://github.com/sii-research/siiRL.

Zheda Mai, Arpita Chowdhury, Ping Zhang et al. · microsoft-research

Fine-tuning is arguably the most straightforward way to tailor a pre-trained model (e.g., a foundation model) to downstream applications, but it also comes with the risk of losing valuable knowledge the model had learned in pre-training. For example, fine-tuning a pre-trained classifier capable of recognizing a large number of classes to master a subset of classes at hand is shown to drastically degrade the model's accuracy in the other classes it had previously learned. As such, it is hard to further use the fine-tuned model when it encounters classes beyond the fine-tuning data. In this paper, we systematically dissect the issue, aiming to answer the fundamental question, "What has been damaged in the fine-tuned model?" To our surprise, we find that the fine-tuned model neither forgets the relationship among the other classes nor degrades the features to recognize these classes. Instead, the fine-tuned model often produces more discriminative features for these other classes, even if they were missing during fine-tuning! {What really hurts the accuracy is the discrepant logit scales between the fine-tuning classes and the other classes}, implying that a simple post-processing calibration would bring back the pre-trained model's capability and at the same time unveil the feature improvement over all classes. We conduct an extensive empirical study to demonstrate the robustness of our findings and provide preliminary explanations underlying them, suggesting new directions for future theoretical analysis. Our code is available at https://github.com/OSU-MLB/Fine-Tuning-Is-Fine-If-Calibrated.

Ke Yang, Sixian Wang, Jincheng Dai et al.

In this paper, we aim to redesign the vision Transformer (ViT) as a new backbone to realize semantic image transmission, termed wireless image transmission transformer (WITT). Previous works build upon convolutional neural networks (CNNs), which are inefficient in capturing global dependencies, resulting in degraded end-to-end transmission performance especially for high-resolution images. To tackle this, the proposed WITT employs Swin Transformers as a more capable backbone to extract long-range information. Different from ViTs in image classification tasks, WITT is highly optimized for image transmission while considering the effect of the wireless channel. Specifically, we propose a spatial modulation module to scale the latent representations according to channel state information, which enhances the ability of a single model to deal with various channel conditions. As a result, extensive experiments verify that our WITT attains better performance for different image resolutions, distortion metrics, and channel conditions. The code is available at https://github.com/KeYang8/WITT.

Guangyu Wang, Jingkun Yue, Siqi Zhang et al.

A central goal of biomedicine is to understand, predict and ultimately control the dynamic mechanisms by which biological systems respond to perturbations, disease progression and therapeutic intervention. Although foundation models and large language models have accelerated biomedical data interpretation, most current systems remain focused on static pattern recognition rather than prospective simulation of biological futures. Here we propose biomedical world models as a paradigm for AI-driven discovery. These models learn latent representations of molecular, cellular, tissue and clinical states, together with intervention-conditioned dynamics that allow future trajectories to be simulated before actions are taken. We discuss how biomedical world models could function as data engines, environment simulators and scientific planning substrates across applications including virtual cells, organoids, virtual patients and surgical simulation. We outline the data infrastructure, evaluation benchmarks, safety constraints and governance frameworks required. Biomedical world models may provide a foundation for simulation-guided, closed-loop and experimentally actionable biomedical discovery.

Thai-Hoang Pham, Xueru Zhang, Ping Zhang

As machine learning (ML) algorithms are increasingly used in high-stakes applications, concerns have arisen that they may be biased against certain social groups. Although many approaches have been proposed to make ML models fair, they typically rely on the assumption that data distributions in training and deployment are identical. Unfortunately, this is commonly violated in practice and a model that is fair during training may lead to an unexpected outcome during its deployment. Although the problem of designing robust ML models under dataset shifts has been widely studied, most existing works focus only on the transfer of accuracy. In this paper, we study the transfer of both fairness and accuracy under domain generalization where the data at test time may be sampled from never-before-seen domains. We first develop theoretical bounds on the unfairness and expected loss at deployment, and then derive sufficient conditions under which fairness and accuracy can be perfectly transferred via invariant representation learning. Guided by this, we design a learning algorithm such that fair ML models learned with training data still have high fairness and accuracy when deployment environments change. Experiments on real-world data validate the proposed algorithm. Model implementation is available at https://github.com/pth1993/FATDM.

Sixian Wang, Jincheng Dai, Zijian Liang et al.

In this paper, we design a new class of high-efficiency deep joint source-channel coding methods to achieve end-to-end video transmission over wireless channels. The proposed methods exploit nonlinear transform and conditional coding architecture to adaptively extract semantic features across video frames, and transmit semantic feature domain representations over wireless channels via deep joint source-channel coding. Our framework is collected under the name deep video semantic transmission (DVST). In particular, benefiting from the strong temporal prior provided by the feature domain context, the learned nonlinear transform function becomes temporally adaptive, resulting in a richer and more accurate entropy model guiding the transmission of current frame. Accordingly, a novel rate adaptive transmission mechanism is developed to customize deep joint source-channel coding for video sources. It learns to allocate the limited channel bandwidth within and among video frames to maximize the overall transmission performance. The whole DVST design is formulated as an optimization problem whose goal is to minimize the end-to-end transmission rate-distortion performance under perceptual quality metrics or machine vision task performance metrics. Across standard video source test sequences and various communication scenarios, experiments show that our DVST can generally surpass traditional wireless video coded transmission schemes. The proposed DVST framework can well support future semantic communications due to its video content-aware and machine vision task integration abilities.

Jingheng Zheng, Hui Tian, Wanli Ni et al.

Over-the-air federated learning (AirFL) allows devices to train a learning model in parallel and synchronize their local models using over-the-air computation. The integrity of AirFL is vulnerable due to the obscurity of the local models aggregated over-the-air. This paper presents a novel framework to balance the accuracy and integrity of AirFL, where multi-antenna devices and base station (BS) are jointly optimized with a reconfigurable intelligent surface (RIS). The key contributions include a new and non-trivial problem jointly considering the model accuracy and integrity of AirFL, and a new framework that transforms the problem into tractable subproblems. Under perfect channel state information (CSI), the new framework minimizes the aggregated model's distortion and retains the local models' recoverability by optimizing the transmit beamformers of the devices, the receive beamformers of the BS, and the RIS configuration in an alternating manner. Under imperfect CSI, the new framework delivers a robust design of the beamformers and RIS configuration to combat non-negligible channel estimation errors. As corroborated experimentally, the novel framework can achieve comparable accuracy to the ideal FL while preserving local model recoverability under perfect CSI, and improve the accuracy when the number of receive antennas is small or moderate under imperfect CSI.

Jincheng Dai, Ping Zhang, Kai Niu et al.

Classical communication paradigms focus on accurately transmitting bits over a noisy channel, and Shannon theory provides a fundamental theoretical limit on the rate of reliable communications. In this approach, bits are treated equally, and the communication system is oblivious to what meaning these bits convey or how they would be used. Future communications towards intelligence and conciseness will predictably play a dominant role, and the proliferation of connected intelligent agents requires a radical rethinking of coded transmission paradigm to support the new communication morphology on the horizon. The recent concept of "semantic communications" offers a promising research direction. Injecting semantic guidance into the coded transmission design to achieve semantics-aware communications shows great potential for further breakthrough in effectiveness and reliability. This article sheds light on semantics-guided source and channel coding as a transmission paradigm of semantic communications, which exploits both data semantics diversity and wireless channel diversity together to boost the whole system performance. We present the general system architecture and key techniques, and indicate some open issues on this topic.

Xinyu Gao, Wenqiang Yi, Yuanwei Liu et al.

Simultaneously transmitting and reflecting reconfigurable intelligent surfaces (STAR-RISs) is a promising passive device that contributes to a full-space coverage via transmitting and reflecting the incident signal simultaneously. As a new paradigm in wireless communications, how to analyze the coverage and capacity performance of STAR-RISs becomes essential but challenging. To solve the coverage and capacity optimization (CCO) problem in STAR-RIS assisted networks, a multi-objective proximal policy optimization (MO-PPO) algorithm is proposed to handle long-term benefits than conventional optimization algorithms. To strike a balance between each objective, the MO-PPO algorithm provides a set of optimal solutions to form a Pareto front (PF), where any solution on the PF is regarded as an optimal result. Moreover, in order to improve the performance of the MO-PPO algorithm, two update strategies, i.e., action-value-based update strategy (AVUS) and loss function-based update strategy (LFUS), are investigated. For the AVUS, the improved point is to integrate the action values of both coverage and capacity and then update the loss function. For the LFUS, the improved point is only to assign dynamic weights for both loss functions of coverage and capacity, while the weights are calculated by a min-norm solver at every update. The numerical results demonstrated that the investigated update strategies outperform the fixed weights MO optimization algorithms in different cases, which includes a different number of sample grids, the number of STAR-RISs, the number of elements in the STAR-RISs, and the size of STAR-RISs. Additionally, the STAR-RIS assisted networks achieve better performance than conventional wireless networks without STAR-RISs. Moreover, with the same bandwidth, millimeter wave is able to provide higher capacity than sub-6 GHz, but at a cost of smaller coverage.

Wangjun Jiang, Dingyou Ma, Zhiqing Wei et al.

Recent advances in wireless communication with the enormous demands of sensing ability have given rise to the integrated sensing and communication (ISAC) technology, among which passive sensing plays an important role. The main challenge of passive sensing is how to achieve high sensing performance in the condition of communication demodulation errors. In this paper, we propose an ISAC network (ISAC-NET) that combines passive sensing with communication signal detection by using model-driven deep learning (DL). Dissimilar to existing passive sensing algorithms that first demodulate the transmitted symbols and then obtain passive sensing results from the demodulated symbols, ISAC-NET obtains passive sensing results and communication demodulated symbols simultaneously. Different from the data-driven DL method, we adopt the block-by-block signal processing method that divides the ISAC-NET into the passive sensing module, signal detection module and channel reconstruction module. From the simulation results, ISAC-NET obtains better communication performance than the traditional signal demodulation algorithm, which is close to OAMP-Net2. Compared to the 2D-DFT algorithm, ISAC-NET demonstrates significantly enhanced sensing performance. In summary, ISAC-NET is a promising tool for passive sensing and communication in wireless communications.

Weizhi Li, Haotai Liang, Chen Dong et al.

Semantic communication serves as a novel paradigm and attracts the broad interest of researchers. One critical aspect of it is the multi-user semantic communication theory, which can further promote its application to the practical network environment. While most existing works focused on the design of end-to-end single-user semantic transmission, a novel non-orthogonal multiple access (NOMA)-based multi-user semantic communication system named NOMASC is proposed in this paper. The proposed system can support semantic tranmission of multiple users with diverse modalities of source information. To avoid high demand for hardware, an asymmetric quantizer is employed at the end of the semantic encoder for discretizing the continuous full-resolution semantic feature. In addition, a neural network model is proposed for mapping the discrete feature into self-learned symbols and accomplishing intelligent multi-user detection (MUD) at the receiver. Simulation results demonstrate that the proposed system holds good performance in non-orthogonal transmission of multiple user signals and outperforms the other methods, especially at low-to-medium SNRs. Moreover, it has high robustness under various simulation settings and mismatched test scenarios.

Deniz Gündüz, Michèle A. Wigger, Tze-Yang Tung et al.

Semantic- and task-oriented communication has emerged as a promising approach to reducing the latency and bandwidth requirements of next-generation mobile networks by transmitting only the most relevant information needed to complete a specific task at the receiver. This is particularly advantageous for machine-oriented communication of high data rate content, such as images and videos, where the goal is rapid and accurate inference, rather than perfect signal reconstruction. While semantic- and task-oriented compression can be implemented in conventional communication systems, joint source-channel coding (JSCC) offers an alternative end-to-end approach by optimizing compression and channel coding together, or even directly mapping the source signal to the modulated waveform. Although all digital communication systems today rely on separation, thanks to its modularity, JSCC is known to achieve higher performance in finite blocklength scenarios, and to avoid cliff and the levelling-off effects in time-varying channel scenarios. This article provides an overview of the information theoretic foundations of JSCC, surveys practical JSCC designs over the decades, and discusses the reasons for their limited adoption in practical systems. We then examine the recent resurgence of JSCC, driven by the integration of deep learning techniques, particularly through DeepJSCC, highlighting its many surprising advantages in various scenarios. Finally, we discuss why it may be time to reconsider today's strictly separate architectures, and reintroduce JSCC to enable high-fidelity, low-latency communications in critical applications such as autonomous driving, drone surveillance, or wearable systems.

Changchang Yin, Pin-Yu Chen, Bingsheng Yao et al.

Sepsis is the leading cause of in-hospital mortality in the USA. Early sepsis onset prediction and diagnosis could significantly improve the survival of sepsis patients. Existing predictive models are usually trained on high-quality data with few missing information, while missing values widely exist in real-world clinical scenarios (especially in the first hours of admissions to the hospital), which causes a significant decrease in accuracy and an increase in uncertainty for the predictive models. The common method to handle missing values is imputation, which replaces the unavailable variables with estimates from the observed data. The uncertainty of imputation results can be propagated to the sepsis prediction outputs, which have not been studied in existing works on either sepsis prediction or uncertainty quantification. In this study, we first define such propagated uncertainty as the variance of prediction output and then introduce uncertainty propagation methods to quantify the propagated uncertainty. Moreover, for the potential high-risk patients with low confidence due to limited observations, we propose a robust active sensing algorithm to increase confidence by actively recommending clinicians to observe the most informative variables. We validate the proposed models in both publicly available data (i.e., MIMIC-III and AmsterdamUMCdb) and proprietary data in The Ohio State University Wexner Medical Center (OSUWMC). The experimental results show that the propagated uncertainty is dominant at the beginning of admissions to hospitals and the proposed algorithm outperforms state-of-the-art active sensing methods. Finally, we implement a SepsisLab system for early sepsis prediction and active sensing based on our pre-trained models. Clinicians and potential sepsis patients can benefit from the system in early prediction and diagnosis of sepsis.

Jianxun Ren, Ning An, Youjia Zhang et al.

Cortical surface registration plays a crucial role in aligning cortical functional and anatomical features across individuals. However, conventional registration algorithms are computationally inefficient. Recently, learning-based registration algorithms have emerged as a promising solution, significantly improving processing efficiency. Nonetheless, there remains a gap in the development of a learning-based method that exceeds the state-of-the-art conventional methods simultaneously in computational efficiency, registration accuracy, and distortion control, despite the theoretically greater representational capabilities of deep learning approaches. To address the challenge, we present SUGAR, a unified unsupervised deep-learning framework for both rigid and non-rigid registration. SUGAR incorporates a U-Net-based spherical graph attention network and leverages the Euler angle representation for deformation. In addition to the similarity loss, we introduce fold and multiple distortion losses, to preserve topology and minimize various types of distortions. Furthermore, we propose a data augmentation strategy specifically tailored for spherical surface registration, enhancing the registration performance. Through extensive evaluation involving over 10,000 scans from 7 diverse datasets, we showed that our framework exhibits comparable or superior registration performance in accuracy, distortion, and test-retest reliability compared to conventional and learning-based methods. Additionally, SUGAR achieves remarkable sub-second processing times, offering a notable speed-up of approximately 12,000 times in registering 9,000 subjects from the UK Biobank dataset in just 32 minutes. This combination of high registration performance and accelerated processing time may greatly benefit large-scale neuroimaging studies.

Shao Zhang, Jianing Yu, Xuhai Xu et al.

Today's AI systems for medical decision support often succeed on benchmark datasets in research papers but fail in real-world deployment. This work focuses on the decision making of sepsis, an acute life-threatening systematic infection that requires an early diagnosis with high uncertainty from the clinician. Our aim is to explore the design requirements for AI systems that can support clinical experts in making better decisions for the early diagnosis of sepsis. The study begins with a formative study investigating why clinical experts abandon an existing AI-powered Sepsis predictive module in their electrical health record (EHR) system. We argue that a human-centered AI system needs to support human experts in the intermediate stages of a medical decision-making process (e.g., generating hypotheses or gathering data), instead of focusing only on the final decision. Therefore, we build SepsisLab based on a state-of-the-art AI algorithm and extend it to predict the future projection of sepsis development, visualize the prediction uncertainty, and propose actionable suggestions (i.e., which additional laboratory tests can be collected) to reduce such uncertainty. Through heuristic evaluation with six clinicians using our prototype system, we demonstrate that SepsisLab enables a promising human-AI collaboration paradigm for the future of AI-assisted sepsis diagnosis and other high-stakes medical decision making.

Miao Yan, Ping Zhang, Haofei Zhang et al.

Thermal infrared (TIR) tracking is pivotal in computer vision tasks due to its all-weather imaging capability. Traditional tracking methods predominantly rely on hand-crafted features, and while deep learning has introduced correlation filtering techniques, these are often constrained by rudimentary correlation operations. Furthermore, transformer-based approaches tend to overlook temporal and coordinate information, which is critical for TIR tracking that lacks texture and color information. In this paper, to address these issues, we apply natural language modeling to TIR tracking and propose a coordinate-aware thermal infrared tracking model called NLMTrack, which enhances the utilization of coordinate and temporal information. NLMTrack applies an encoder that unifies feature extraction and feature fusion, which simplifies the TIR tracking pipeline. To address the challenge of low detail and low contrast in TIR images, on the one hand, we design a multi-level progressive fusion module that enhances the semantic representation and incorporates multi-scale features. On the other hand, the decoder combines the TIR features and the coordinate sequence features using a causal transformer to generate the target sequence step by step. Moreover, we explore an adaptive loss aimed at elevating tracking accuracy and a simple template update strategy to accommodate the target's appearance variations. Experiments show that NLMTrack achieves state-of-the-art performance on multiple benchmarks. The Code is publicly available at \url{https://github.com/ELOESZHANG/NLMTrack}.

Jincheng Dai, Sixian Wang, Ke Yang et al.

The emerging field semantic communication is driving the research of end-to-end data transmission. By utilizing the powerful representation ability of deep learning models, learned data transmission schemes have exhibited superior performance than the established source and channel coding methods. While, so far, research efforts mainly concentrated on architecture and model improvements toward a static target domain. Despite their successes, such learned models are still suboptimal due to the limitations in model capacity and imperfect optimization and generalization, particularly when the testing data distribution or channel response is different from that adopted for model training, as is likely to be the case in real-world. To tackle this, we propose a novel online learned joint source and channel coding approach that leverages the deep learning model's overfitting property. Specifically, we update the off-the-shelf pre-trained models after deployment in a lightweight online fashion to adapt to the distribution shifts in source data and environment domain. We take the overfitting concept to the extreme, proposing a series of implementation-friendly methods to adapt the codec model or representations to an individual data or channel state instance, which can further lead to substantial gains in terms of the bandwidth ratio-distortion performance. The proposed methods enable the communication-efficient adaptation for all parameters in the network without sacrificing decoding speed. Our experiments, including user study, on continually changing target source data and wireless channel environments, demonstrate the effectiveness and efficiency of our approach, on which we outperform existing state-of-the-art engineered transmission scheme (VVC combined with 5G LDPC coded transmission).

Yong Xiao, Xubo Li, Haoran Zhou et al.

Agentic AI networking (AgentNet) is a novel AI-native networking paradigm in which a large number of specialized AI agents collaborate to perform autonomous decision-making, dynamic environmental adaptation, and complex missions. It has the potential to facilitate real-time network management and optimization functions, including self-configuration, self-optimization, and self-adaptation across diverse and complex environments. This paper proposes SANet, a novel semantic-aware AgentNet architecture for wireless networks that can infer the semantic goal of the user and automatically assign agents associated with different layers of the network to fulfill the inferred goal. Motivated by the fact that AgentNet is a decentralized framework in which collaborating agents may generally have different and even conflicting objectives, we formulate the decentralized optimization of SANet as a multi-agent multi-objective problem, and focus on finding the Pareto-optimal solution for agents with distinct and potentially conflicting objectives. We propose three novel metrics for evaluating SANet. Furthermore, we develop a model partition and sharing (MoPS) framework in which large models, e.g., deep learning models, of different agents can be partitioned into shared and agent-specific parts that are jointly constructed and deployed according to agents' local computational resources. Two decentralized optimization algorithms are proposed. We derive theoretical bounds and prove that there exists a three-way tradeoff among optimization, generalization, and conflicting errors. We develop an open-source RAN and core network-based hardware prototype that implements agents to interact with three different layers of the network. Experimental results show that the proposed framework achieved performance gains of up to 14.61% while requiring only 44.37% of FLOPs required by state-of-the-art algorithms.

Rui Meng, Song Gao, Bingxuan Xu et al.

Semantic Communication (SemCom), leveraging its significant advantages in transmission efficiency and reliability, has emerged as a core technology for constructing future intellicise (intelligent and concise) wireless networks. However, intelligent attacks represented by semantic eavesdropping pose severe challenges to the security of SemCom. To address this challenge, Semantic Steganographic Communication (SemSteCom) achieves ``invisible'' encryption by implicitly embedding private semantic information into cover modality carriers. The state-of-the-art study has further introduced generative diffusion models to directly generate stega images without relying on original cover images, effectively enhancing steganographic capacity. Nevertheless, the recovery process of private images is highly dependent on the guidance of private semantic keys, which may be inferred by intelligent eavesdroppers, thereby introducing new security threats. To address this issue, we propose an Agentic AI-driven SemSteCom (AgentSemSteCom) scheme, which includes semantic extraction, digital token controlled reference image generation, coverless steganography, semantic codec, and optional task-oriented enhancement modules. The proposed AgentSemSteCom scheme obviates the need for both cover images and private semantic keys, thereby boosting steganographic capacity while reinforcing transmission security. The simulation results on open-source datasets verify that, AgentSemSteCom achieves better transmission quality and higher security levels than the baseline scheme.

Bo Qian, Hao Chen, Xiangning Wang et al.

Computer-assisted automatic analysis of diabetic retinopathy (DR) is of great importance in reducing the risks of vision loss and even blindness. Ultra-wide optical coherence tomography angiography (UW-OCTA) is a non-invasive and safe imaging modality in DR diagnosis system, but there is a lack of publicly available benchmarks for model development and evaluation. To promote further research and scientific benchmarking for diabetic retinopathy analysis using UW-OCTA images, we organized a challenge named "DRAC - Diabetic Retinopathy Analysis Challenge" in conjunction with the 25th International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI 2022). The challenge consists of three tasks: segmentation of DR lesions, image quality assessment and DR grading. The scientific community responded positively to the challenge, with 11, 12, and 13 teams from geographically diverse institutes submitting different solutions in these three tasks, respectively. This paper presents a summary and analysis of the top-performing solutions and results for each task of the challenge. The obtained results from top algorithms indicate the importance of data augmentation, model architecture and ensemble of networks in improving the performance of deep learning models. These findings have the potential to enable new developments in diabetic retinopathy analysis. The challenge remains open for post-challenge registrations and submissions for benchmarking future methodology developments.

Ruiyao Liu, Hui Shen, Ping Zhang et al.

Modern generative models have demonstrated the ability to solve challenging mathematical problems. In many real-world settings, however, mathematical solutions must be expressed visually through diagrams, plots, geometric constructions, and structured symbolic layouts, where correctness depends on precise visual composition. This naturally raises the question of whether generative models can still do so when the answer must be rendered visually rather than written in text? To study this problem, we introduce MathGen, a rigorous benchmark of 900 problems spanning seven core domains, each paired with an executable verifier under a Script-as-a-Judge protocol for deterministic and objective evaluation. Experiments on representative open-source and proprietary text-to-image models show that mathematical fidelity remains a major bottleneck: even the best closed-source model reaches only 42.0% overall accuracy, while open-source models achieve just ~ 1-11%, often near 0% on structured tasks. Overall, current T2I models remain far from competent at even elementary mathematical visual generation.

Changchang Yin, Ruoqi Liu, Jeffrey Caterino et al.

Despite intense efforts in basic and clinical research, an individualized ventilation strategy for critically ill patients remains a major challenge. Recently, dynamic treatment regime (DTR) with reinforcement learning (RL) on electronic health records (EHR) has attracted interest from both the healthcare industry and machine learning research community. However, most learned DTR policies might be biased due to the existence of confounders. Although some treatment actions non-survivors received may be helpful, if confounders cause the mortality, the training of RL models guided by long-term outcomes (e.g., 90-day mortality) would punish those treatment actions causing the learned DTR policies to be suboptimal. In this study, we develop a new deconfounding actor-critic network (DAC) to learn optimal DTR policies for patients. To alleviate confounding issues, we incorporate a patient resampling module and a confounding balance module into our actor-critic framework. To avoid punishing the effective treatment actions non-survivors received, we design a short-term reward to capture patients' immediate health state changes. Combining short-term with long-term rewards could further improve the model performance. Moreover, we introduce a policy adaptation method to successfully transfer the learned model to new-source small-scale datasets. The experimental results on one semi-synthetic and two different real-world datasets show the proposed model outperforms the state-of-the-art models. The proposed model provides individualized treatment decisions for mechanical ventilation that could improve patient outcomes.

Penghui Niu, Taotao Cai, Suqi Zhang et al.

The inherent intermittency and high-frequency variability of solar irradiance, particularly during rapid cloud advection, present significant stability challenges to high-penetration photovoltaic grids. Although multimodal forecasting has emerged as a viable mitigation strategy, existing architectures predominantly rely on shallow feature concatenation and binary cloud segmentation, thereby failing to capture the fine-grained optical features of clouds and the complex spatiotemporal coupling between visual and meteorological modalities. To bridge this gap, this paper proposes M3S-Net, a novel multimodal feature fusion network based on multi-scale data for ultra-short-term PV power forecasting. First, a multi-scale partial channel selection network leverages partial convolutions to explicitly isolate the boundary features of optically thin clouds, effectively transcending the precision limitations of coarse-grained binary masking. Second, a multi-scale sequence to image analysis network employs Fast Fourier Transform (FFT)-based time-frequency representation to disentangle the complex periodicity of meteorological data across varying time horizons. Crucially, the model incorporates a cross-modal Mamba interaction module featuring a novel dynamic C-matrix swapping mechanism. By exchanging state-space parameters between visual and temporal streams, this design conditions the state evolution of one modality on the context of the other, enabling deep structural coupling with linear computational complexity, thus overcoming the limitations of shallow concatenation. Experimental validation on the newly constructed fine-grained PV power dataset demonstrates that M3S-Net achieves a mean absolute error reduction of 6.2% in 10-minute forecasts compared to state-of-the-art baselines. The dataset and source code will be available at https://github.com/she1110/FGPD.

Penghui Niu, Jiashuai She, Taotao Cai et al.

Ground-based cloud image segmentation is a critical research domain for photovoltaic power forecasting. Current deep learning approaches primarily focus on encoder-decoder architectural refinements. However, existing methodologies exhibit several limitations:(1)they rely on dilated convolutions for multi-scale context extraction, lacking the partial feature effectiveness and interoperability of inter-channel;(2)attention-based feature enhancement implementations neglect accuracy-throughput balance; and (3)the decoder modifications fail to establish global interdependencies among hierarchical local features, limiting inference efficiency. To address these challenges, we propose MPCM-Net, a Multi-scale network that integrates Partial attention Convolutions with Mamba architectures to enhance segmentation accuracy and computational efficiency. Specifically, the encoder incorporates MPAC, which comprises:(1)a MPC block with ParCM and ParSM that enables global spatial interaction across multi-scale cloud formations, and (2)a MPA block combining ParAM and ParSM to extract discriminative features with reduced computational complexity. On the decoder side, a M2B is employed to mitigate contextual loss through a SSHD that maintains linear complexity while enabling deep feature aggregation across spatial and scale dimensions. As a key contribution to the community, we also introduce and release a dataset CSRC, which is a clear-label, fine-grained segmentation benchmark designed to overcome the critical limitations of existing public datasets. Extensive experiments on CSRC demonstrate the superior performance of MPCM-Net over state-of-the-art methods, achieving an optimal balance between segmentation accuracy and inference speed. The dataset and source code will be available at https://github.com/she1110/CSRC.

Changyuan Zhao, Jiacheng Wang, Ruichen Zhang et al.

Deep joint source-channel coding (JSCC) has emerged as a promising paradigm for semantic communication, delivering significant performance gains over conventional separate coding schemes. However, existing JSCC frameworks remain vulnerable to physical-layer adversarial threats, such as pilot spoofing and subcarrier jamming, compromising semantic fidelity. In this paper, we propose SecDiff, a plug-and-play, diffusion-aided decoding framework that significantly enhances the security and robustness of deep JSCC under adversarial wireless environments. Different from prior diffusion-guided JSCC methods that suffer from high inference latency, SecDiff employs pseudoinverse-guided sampling and adaptive guidance weighting, enabling flexible step-size control and efficient semantic reconstruction. To counter jamming attacks, we introduce a power-based subcarrier masking strategy and recast recovery as a masked inpainting problem, solved via diffusion guidance. For pilot spoofing, we formulate channel estimation as a blind inverse problem and develop an expectation-minimization (EM)-driven reconstruction algorithm, guided jointly by reconstruction loss and a channel operator. Notably, our method alternates between pilot recovery and channel estimation, enabling joint refinement of both variables throughout the diffusion process. Extensive experiments over orthogonal frequency-division multiplexing (OFDM) channels under adversarial conditions show that SecDiff outperforms existing secure and generative JSCC baselines by achieving a favorable trade-off between reconstruction quality and computational cost. This balance makes SecDiff a promising step toward practical, low-latency, and attack-resilient semantic communications.

Wei Zhang, Ping Zhang, Jian Dong et al.

The effectiveness of ad creatives is greatly influenced by their visual appearance. Advertising platforms can generate ad creatives with different appearances by combining creative elements provided by advertisers. However, with the increasing number of ad creative elements, it becomes challenging to select a suitable combination from the countless possibilities. The industry's mainstream approach is to select individual creative elements independently, which often overlooks the importance of interaction between creative elements during the modeling process. In response, this paper proposes a Cross-Element Combinatorial Selection framework for multiple creative elements, termed CECS. In the encoder process, a cross-element interaction is adopted to dynamically adjust the expression of a single creative element based on the current candidate creatives. In the decoder process, the creative combination problem is transformed into a cascade selection problem of multiple creative elements. A pointer mechanism with a cascade design is used to model the associations among candidates. Comprehensive experiments on real-world datasets show that CECS achieved the SOTA score on offline metrics. Moreover, the CECS algorithm has been deployed in our industrial application, resulting in a significant 6.02% CTR and 10.37% GMV lift, which is beneficial to the business.

Zishan Gu, Changchang Yin, Fenglin Liu et al.

Large Vision Language Models (LVLMs) have recently achieved superior performance in various tasks on natural image and text data, which inspires a large amount of studies for LVLMs fine-tuning and training. Despite their advancements, there has been scant research on the robustness of these models against hallucination when fine-tuned on smaller datasets. In this study, we introduce a new benchmark dataset, the Medical Visual Hallucination Test (MedVH), to evaluate the hallucination of domain-specific LVLMs. MedVH comprises five tasks to evaluate hallucinations in LVLMs within the medical context, which includes tasks for comprehensive understanding of textual and visual input, as well as long textual response generation. Our extensive experiments with both general and medical LVLMs reveal that, although medical LVLMs demonstrate promising performance on standard medical tasks, they are particularly susceptible to hallucinations, often more so than the general models, raising significant concerns about the reliability of these domain-specific models. For medical LVLMs to be truly valuable in real-world applications, they must not only accurately integrate medical knowledge but also maintain robust reasoning abilities to prevent hallucination. Our work paves the way for future evaluations of these studies.

Hongliang Zeng, Ping Zhang, Chengjiong Wu et al.

Precise perception of articulated objects is vital for empowering service robots. Recent studies mainly focus on point cloud, a single-modal approach, often neglecting vital texture and lighting details and assuming ideal conditions like optimal viewpoints, unrepresentative of real-world scenarios. To address these limitations, we introduce MARS, a novel framework for articulated object characterization. It features a multi-modal fusion module utilizing multi-scale RGB features to enhance point cloud features, coupled with reinforcement learning-based active sensing for autonomous optimization of observation viewpoints. In experiments conducted with various articulated object instances from the PartNet-Mobility dataset, our method outperformed current state-of-the-art methods in joint parameter estimation accuracy. Additionally, through active sensing, MARS further reduces errors, demonstrating enhanced efficiency in handling suboptimal viewpoints. Furthermore, our method effectively generalizes to real-world articulated objects, enhancing robot interactions. Code is available at https://github.com/robhlzeng/MARS.

Eleonora Grassucci, Yuki Mitsufuji, Ping Zhang et al.

Semantic communication is poised to play a pivotal role in shaping the landscape of future AI-driven communication systems. Its challenge of extracting semantic information from the original complex content and regenerating semantically consistent data at the receiver, possibly being robust to channel corruptions, can be addressed with deep generative models. This ICASSP special session overview paper discloses the semantic communication challenges from the machine learning perspective and unveils how deep generative models will significantly enhance semantic communication frameworks in dealing with real-world complex data, extracting and exploiting semantic information, and being robust to channel corruptions. Alongside establishing this emerging field, this paper charts novel research pathways for the next generative semantic communication frameworks.

Zhuopeng Li, Lu Li, Zeyu Ma et al.

Synthesizing free-view photo-realistic images is an important task in multimedia. With the development of advanced driver assistance systems~(ADAS) and their applications in autonomous vehicles, experimenting with different scenarios becomes a challenge. Although the photo-realistic street scenes can be synthesized by image-to-image translation methods, which cannot produce coherent scenes due to the lack of 3D information. In this paper, a large-scale neural rendering method is proposed to synthesize the autonomous driving scene~(READ), which makes it possible to synthesize large-scale driving scenarios on a PC through a variety of sampling schemes. In order to represent driving scenarios, we propose an ω rendering network to learn neural descriptors from sparse point clouds. Our model can not only synthesize realistic driving scenes but also stitch and edit driving scenes. Experiments show that our model performs well in large-scale driving scenarios.

Jinke Ren, Zezhong Zhang, Jie Xu et al.

Semantic communication is widely touted as a key technology for propelling the sixth-generation (6G) wireless networks. However, providing effective semantic representation is quite challenging in practice. To address this issue, this article takes a crack at exploiting semantic knowledge base (KB) to usher in a new era of generative semantic communication. Via semantic KB, source messages can be characterized in low-dimensional subspaces without compromising their desired meanings, thus significantly enhancing the communication efficiency. The fundamental principle of semantic KB is first introduced, and a generative semantic communication architecture is developed by presenting three sub-KBs, namely source, task, and channel KBs. Then, the detailed construction approaches for each sub-KB are described, followed by their utilization in terms of semantic coding and transmission. A case study is also provided to showcase the superiority of generative semantic communication over conventional syntactic communication and classical semantic communication. In a nutshell, this article establishes a scientific foundation for the exciting uncharted frontier of generative semantic communication.

Zheda Mai, Ping Zhang, Cheng-Hao Tu et al.

Parameter-efficient fine-tuning (PEFT) has attracted significant attention due to the growth of pre-trained model sizes and the need to fine-tune (FT) them for superior downstream performance. Despite a surge in new PEFT methods, a systematic study to understand their performance and suitable application scenarios is lacking, leaving questions like "when to apply PEFT" and "which method to use" largely unanswered, especially in visual recognition. In this paper, we conduct a unifying empirical study of representative PEFT methods with Vision Transformers. We systematically tune their hyperparameters to fairly compare their accuracy on downstream tasks. Our study offers a practical user guide and unveils several new insights. First, if tuned carefully, different PEFT methods achieve similar accuracy in the low-shot benchmark VTAB-1K. This includes simple approaches like FT the bias terms that were reported inferior. Second, despite similar accuracy, we find that PEFT methods make different mistakes and high-confidence predictions, likely due to their different inductive biases. Such an inconsistency (or complementarity) opens up the opportunity for ensemble methods, and we make preliminary attempts at this. Third, going beyond the commonly used low-shot tasks, we find that PEFT is also useful in many-shot regimes, achieving comparable or better accuracy than full FT while using significantly fewer parameters. Lastly, we investigate PEFT's ability to preserve a pre-trained model's robustness to distribution shifts (e.g., CLIP). Perhaps not surprisingly, PEFT approaches outperform full FT alone. However, with weight-space ensembles, full FT can better balance target distribution and distribution shift performance, suggesting a future research direction for robust PEFT.

Ruhan Liu, Jiajia Li, Yang Wen et al.

Objective: COVID-19 has spread worldwide and made a huge influence across the world. Modeling the infectious spread situation of COVID-19 is essential to understand the current condition and to formulate intervention measurements. Epidemiological equations based on the SEIR model simulate disease development. The traditional parameter estimation method to solve SEIR equations could not precisely fit real-world data due to different situations, such as social distancing policies and intervention strategies. Additionally, learning-based models achieve outstanding fitting performance, but cannot visualize mechanisms. Methods: Thus, we propose a deep dynamic epidemiological (DDE) method that combines epidemiological equations and deep-learning advantages to obtain high accuracy and visualization. The DDE contains deep networks to fit the effect function to simulate the ever-changing situations based on the neural ODE method in solving variants' equations, ensuring the fitting performance of multi-level areas. Results: We introduce four SEIR variants to fit different situations in different countries and regions. We compare our DDE method with traditional parameter estimation methods (Nelder-Mead, BFGS, Powell, Truncated Newton Conjugate-Gradient, Neural ODE) in fitting the real-world data in the cases of countries (the USA, Columbia, South Africa) and regions (Wuhan in China, Piedmont in Italy). Our DDE method achieves the best Mean Square Error and Pearson coefficient in all five areas. Further, compared with the state-of-art learning-based approaches, the DDE outperforms all techniques, including LSTM, RNN, GRU, Random Forest, Extremely Random Trees, and Decision Tree. Conclusion: DDE presents outstanding predictive ability and visualized display of the changes in infection rates in different regions and countries.

Hai-Long Qin, Jincheng Dai, Guo Lu et al.

Semantic communications mark a paradigm shift from bit-accurate transmission toward meaning-centric communication, essential as wireless systems approach theoretical capacity limits. The emergence of generative AI has catalyzed generative semantic communications, where receivers reconstruct content from minimal semantic cues by leveraging learned priors. Among generative approaches, diffusion models stand out for their superior generation quality, stable training dynamics, and rigorous theoretical foundations. However, the field currently lacks systematic guidance connecting diffusion techniques to communication system design, forcing researchers to navigate disparate literatures. This article provides the first comprehensive tutorial on diffusion models for generative semantic communications. We present score-based diffusion foundations and systematically review three technical pillars: conditional diffusion for controllable generation, efficient diffusion for accelerated inference, and generalized diffusion for cross-domain adaptation. In addition, we introduce an inverse problem perspective that reformulates semantic decoding as posterior inference, bridging semantic communications with computational imaging. Through analysis of human-centric, machine-centric, and agent-centric scenarios, we illustrate how diffusion models enable extreme compression while maintaining semantic fidelity and robustness. By bridging generative AI innovations with communication system design, this article aims to establish diffusion models as foundational components of next-generation wireless networks and beyond.

Tong Wu, Zhiyong Chen, Meixia Tao et al.

Lightweight and efficient neural network models for deep joint source-channel coding (JSCC) are crucial for semantic communications. In this paper, we propose a novel JSCC architecture, named MambaJSCC, that achieves state-of-the-art performance with low computational and parameter overhead. MambaJSCC utilizes the visual state space model with channel adaptation (VSSM-CA) blocks as its backbone for transmitting images over wireless channels, where the VSSM-CA primarily consists of the generalized state space models (GSSM) and the zero-parameter, zero-computational channel adaptation method (CSI-ReST). We design the GSSM module, leveraging reversible matrix transformations to express generalized scan expanding operations, and theoretically prove that two GSSM modules can effectively capture global information. We discover that GSSM inherently possesses the ability to adapt to channels, a form of endogenous intelligence. Based on this, we design the CSI-ReST method, which injects channel state information (CSI) into the initial state of GSSM to utilize its native response, and into the residual state to mitigate CSI forgetting, enabling effective channel adaptation without introducing additional computational and parameter overhead. Experimental results show that MambaJSCC not only outperforms existing JSCC methods (e.g., SwinJSCC) across various scenarios but also significantly reduces parameter size, computational overhead, and inference delay.

Doeun Lee, Muge Zhang, Yi Yu et al.

Across medical specialties, clinical practice is anchored in evidence-based guidelines that codify best studied diagnostic and treatment pathways. These pathways routinely fall short for the long tail of real-world care not covered by guidelines. Most medical large language models (LLMs), however, are trained to encode common, guideline-focused medical knowledge in their parameters. Current evaluations test models primarily on recalling and reasoning with this memorized content, often in multiple-choice settings. Given the fundamental importance of evidence-based reasoning in medicine, it is neither feasible nor reliable to depend on memorization in practice. To address this gap, we introduce OGCaReBench, a free-form retrieval-focused benchmark aimed at evaluating LLMs at answering clinical questions that require going beyond typical guidelines. Extracted from published medical case reports and validated by medical experts, OGCaReBench contains long-form clinical questions requiring free-text answers, providing a systematic framework for assessing open-ended medical reasoning in rare, case-based scenarios. Our experiments reveal that even the best-performing baseline (GPT-5.2) correctly answers only 56% of our benchmark with specialized models only reaching 42%. Augmenting models with retrieved medical articles improves this performance to up to 82% (using GPT-5.2) highlighting the importance of evidence-grounding for real-world medical reasoning tasks. This work thus establishes a foundation for benchmarking and advancing both general-purpose and medical LLMs to produce reliable answers in challenging clinical contexts.

Yiqi Zhang, Fangzheng Jiao, Tian Tang et al.

Reinforcement learning with verifiable rewards (RLVR) has recently unlocked strong reasoning capabilities in large language models (LLMs), triggering rapid exploration of new algorithms and data. However, RLVR training is notoriously inefficient: long-tailed rollouts, tool-induced stalls, and asymmetric resource requirements between rollout and training introduce substantial idle time that cannot be eliminated by job-local optimizations such as synchronous pipelining, asynchronous rollout, or colocated execution. We argue that this inefficiency is structural. While idle gaps are unavoidable within individual RLVR jobs, they are largely anti-correlated across jobs and therefore exploitable at the cluster level. Leveraging this observation, we present PlexRL, a cluster-level runtime for multiplexing unified LLM services across RLVR jobs. By centrally managing model placement, state transitions, and function-level scheduling under strict affinity constraints, PlexRL time-slices LLM execution across jobs to fill otherwise idle periods without expensive model migration. Our implementation and evaluations demonstrate that PlexRL significantly improves effective cluster capacity and reduces user GPU hour cost by maximum 37.58% while preserving algorithmic flexibility and introducing minimal per-job overhead.

Sooyoung Jeon, Hongjie Tian, Lemeng Wang et al.

Camera traps are vital for large-scale biodiversity monitoring, yet accurate automated analysis remains challenging due to diverse deployment environments. While the computer vision community has mostly framed this challenge as cross-domain generalization, this perspective overlooks a primary challenge faced by ecological practitioners: maintaining reliable recognition at the fixed site over time, where the dynamic nature of ecosystems introduces profound temporal shifts in both background and animal distributions. To bridge this gap, we present the first unified study of camera-trap species recognition over time. We introduce a realistic benchmark comprising 546 camera traps with a streaming protocol that evaluates models over chronologically ordered intervals. Our end-user-centric study yields four key findings. (1) Biological foundation models (e.g., BioCLIP 2) underperform at numerous sites even in initial intervals, underscoring the necessity of site-specific adaptation. (2) Adaptation is challenging under realistic evaluation: when models are updated using past data and evaluated on future intervals (mirrors real deployment lifecycles), naive adaptation can even degrade below zero-shot performance. (3) We identify two drivers of this difficulty: severe class imbalance and pronounced temporal shift in both species distribution and backgrounds between consecutive intervals. (4) We find that effective integration of model-update and post-processing techniques can largely improve accuracy, though a gap from the upper bounds remains. Finally, we highlight critical open questions, such as predicting when zero-shot models will succeed at a new site and determining whether/when model updates are necessary. Our benchmark and analysis provide actionable deployment guidelines for ecological practitioners while establishing new directions for future research in vision and machine learning.

Yue Hu, Xianghe Pang, Xiaoqi Qin et al.

Collaborative perception allows each agent to enhance its perceptual abilities by exchanging messages with others. It inherently results in a trade-off between perception ability and communication costs. Previous works transmit complete full-frame high-dimensional feature maps among agents, resulting in substantial communication costs. To promote communication efficiency, we propose only transmitting the information needed for the collaborator's downstream task. This pragmatic communication strategy focuses on three key aspects: i) pragmatic message selection, which selects task-critical parts from the complete data, resulting in spatially and temporally sparse feature vectors; ii) pragmatic message representation, which achieves pragmatic approximation of high-dimensional feature vectors with a task-adaptive dictionary, enabling communicating with integer indices; iii) pragmatic collaborator selection, which identifies beneficial collaborators, pruning unnecessary communication links. Following this strategy, we first formulate a mathematical optimization framework for the perception-communication trade-off and then propose PragComm, a multi-agent collaborative perception system with two key components: i) single-agent detection and tracking and ii) pragmatic collaboration. The proposed PragComm promotes pragmatic communication and adapts to a wide range of communication conditions. We evaluate PragComm for both collaborative 3D object detection and tracking tasks in both real-world, V2V4Real, and simulation datasets, OPV2V and V2X-SIM2.0. PragComm consistently outperforms previous methods with more than 32.7K times lower communication volume on OPV2V. Code is available at github.com/PhyllisH/PragComm.

Yuanlong Wang, Weichi Chen, Adrian Rajab et al.

Peripheral Blood Smear (PBS) is a critical microscopic examination in hematopathology that yields whole-slide imaging (WSI). Unlike solid tissue pathology, PBS interpretation focuses on individual cell morphologies rather than tissue architecture, making it distinct in both visual characteristics and diagnostic reasoning. However, current multimodal large language models (MLLMs) for pathology are primarily developed on solid-tissue WSIs and struggle to generalize to PBS. To bridge this gap, we construct PBSInstr, the first vision-language dataset for PBS interpretation, comprising 353 PBS WSIs paired with microscopic impression paragraphs and 29k cell-level image crops annotated with cell type labels and morphological descriptions. To facilitate instruction tuning, PBSInstr further includes 27k question-answer (QA) pairs for cell crops and 1,286 QA pairs for PBS slides. Building upon PBSInstr, we develop PBS-VL, a hematopathology-tailored vision-language model for multi-level PBS interpretation at both cell and slide levels. To comprehensively evaluate PBS understanding, we construct PBSBench, a visual question answering (VQA) benchmark featuring four question categories and six PBS interpretation tasks. Experiments show that PBS-VL outperforms existing general-purpose and pathology MLLMs, underscoring the value of PBS-specific data. We release our code, datasets, and model weights to facilitate future research. Our proposed framework lays the foundation for developing practical AI assistants supporting decision-making in hematopathology.

Jianqiao Chen, Nan Ma, Xiaodong Xu et al.

Digital mapping of semantic features is essential for achieving interoperability between semantic communication and practical digital infrastructure. However, current research efforts predominantly concentrate on analog semantic communication with simplified channel models. To bridge these gaps, we develop a robust vector quantized-enabled digital semantic communication (VQ-DSC-R) system built upon orthogonal frequency division multiplexing (OFDM) transmission. Our work encompasses the framework design of VQ-DSC-R, followed by a comprehensive optimization study. Firstly, we design a Swin Transformer-based backbone for hierarchical semantic feature extraction, integrated with VQ modules that map the features into a shared semantic quantized codebook (SQC) for efficient index transmission. Secondly, we propose a differentiable vector quantization with adaptive noise-variance (ANDVQ) scheme to mitigate quantization errors in SQC, which dynamically adjusts the quantization process using K-nearest neighbor statistics, while exponential moving average mechanism stabilizes SQC training. Thirdly, for robust index transmission over multipath fading channel and noise, we develop a conditional diffusion model (CDM) to refine channel state information, and design an attention-based module to dynamically adapt to channel noise. The entire VQ-DSC-R system is optimized via a three-stage training strategy. Extensive experiments demonstrate superiority of VQ-DSC-R over benchmark schemes, achieving high compression ratios and robust performance in practical scenarios.

Jiwoo Park, Ruoqi Liu, Avani Jagdale et al.

We present ClinicalTrialsHub, an interactive search-focused platform that consolidates all data from ClinicalTrials.gov and augments it by automatically extracting and structuring trial-relevant information from PubMed research articles. Our system effectively increases access to structured clinical trial data by 83.8% compared to relying on ClinicalTrials.gov alone, with potential to make access easier for patients, clinicians, researchers, and policymakers, advancing evidence-based medicine. ClinicalTrialsHub uses large language models such as GPT-5.1 and Gemini-3-Pro to enhance accessibility. The platform automatically parses full-text research articles to extract structured trial information, translates user queries into structured database searches, and provides an attributed question-answering system that generates evidence-grounded answers linked to specific source sentences. We demonstrate its utility through a user study involving clinicians, clinical researchers, and PhD students of pharmaceutical sciences and nursing, and a systematic automatic evaluation of its information extraction and question answering capabilities.

Juntao Li, Haobin Yuan, Ling Luo et al.

Discharge medication recommendation plays a critical role in ensuring treatment continuity, preventing readmission, and improving long-term management for patients with chronic metabolic diseases. This paper present an overview of the CHIP 2025 Shared Task 2 competition, which aimed to develop state-of-the-art approaches for automatically recommending appro-priate discharge medications using real-world Chinese EHR data. For this task, we constructed CDrugRed, a high-quality dataset consisting of 5,894 de-identified hospitalization records from 3,190 patients in China. This task is challenging due to multi-label nature of medication recommendation, het-erogeneous clinical text, and patient-specific variability in treatment plans. A total of 526 teams registered, with 167 and 95 teams submitting valid results to the Phase A and Phase B leaderboards, respectively. The top-performing team achieved the highest overall performance on the final test set, with a Jaccard score of 0.5102, F1 score of 0.6267, demonstrating the potential of advanced large language model (LLM)-based ensemble systems. These re-sults highlight both the promise and remaining challenges of applying LLMs to medication recommendation in Chinese EHRs. The post-evaluation phase remains open at https://tianchi.aliyun.com/competition/entrance/532411/.

Yifei She, Ping Zhang, He Liu et al.

Real-world agentic tasks, unlike synchronous Markov Decision Processes (MDPs), often involve non-blocking actions with variable latencies, creating a fundamental \textit{Temporal Gap} between action initiation and completion. Existing environment-side solutions, such as blocking wrappers or frequent polling, either limit scalability or dilute the agent's context window with redundant observations. In this work, we propose an \textbf{Agent-side Approach} that empowers Large Language Models (LLMs) to actively align their \textit{Cognitive Timeline} with the physical world. By extending the Code-as-Action paradigm to the temporal domain, agents utilize semantic priors and In-Context Learning (ICL) to predict precise waiting durations (\texttt{time.sleep(t)}), effectively synchronizing with asynchronous environment without exhaustive checking. Experiments in a simulated Kubernetes cluster demonstrate that agents can precisely calibrate their internal clocks to minimize both query overhead and execution latency, validating that temporal awareness is a learnable capability essential for autonomous evolution in open-ended environments.

Zijian Liang, Kai Niu, Changshuo Wang et al.

The fundamental limit of natural signal compression has traditionally been characterized by classical rate-distortion (RD) theory through the tradeoff between coding rate and reconstruction distortion, while the rate-distortion-perception (RDP) framework introduces a divergence-based measure of perceptual quality as a modeling principle rather than a theoretically-derived principle, leaving its theoretical origin unclear. In this paper, motivated by a synonymity-based semantic information perspective, we reformulate perceptual reconstruction as recovering any admissible sample within an ideal synonymous set (synset) associated with the source, rather than the source sample itself, and correspondingly establish a synonymous source coding architecture. On this basis, we develop a synonymous variational inference (SVI) analysis framework with a synonymous variational lower bound (SVLBO) for tractable analysis of synset-oriented compression. Within this framework, we establish a synonymity-perception consistency principle, showing that optimal identification of semantic information is theoretically consistent with perceptual optimization. Based on its derivation result, we prove a synonymous RDP tradeoff for the proposed synonymous source coding. These analytical results show that the distributional divergence term arises naturally from the synset-based reconstruction objective, clarify its compatibility with existing RDP formulations and classical RD theory, and suggest the potential advantages of synonymous source coding.

Hui Shen, Xin Wang, Ping Zhang et al.

Vision-language models (VLMs) achieve strong performance on multimodal tasks but suffer from high inference latency due to large model sizes and long multimodal contexts. Speculative decoding has recently emerged as an effective acceleration technique, yet its behavior in VLMs remains insufficiently understood. We introduce MMSpec, the first benchmark for evaluating speculative decoding in vision-language models. MMSpec contains 600 multimodal samples across six task categories and integrates ten representative speculative decoding algorithms under a unified evaluation framework. Our study reveals three key findings: (1) methods designed for text-only LLMs degrade in multimodal scenarios, (2) vision awareness becomes increasingly important at larger batch sizes, and (3) throughput speedup alone does not reliably reflect latency performance. Motivated by these findings, we propose ViSkip, a plug-and-play speculative decoding method that dynamically adapts speculation to vision tokens and achieves state-of-the-art performance.

Jinghao Wang, Ping Zhang, Carter Yagemann

Medical Large Language Models (LLMs) are increasingly deployed for clinical decision support across diverse specialties, yet systematic evaluation of their robustness to adversarial misuse and privacy leakage remains inaccessible to most researchers. Existing security benchmarks require GPU clusters, commercial API access, or protected health data -- barriers that limit community participation in this critical research area. We propose a practical, fully reproducible framework for evaluating medical AI security under realistic resource constraints. Our framework design covers multiple medical specialties stratified by clinical risk -- from high-risk domains such as emergency medicine and psychiatry to general practice -- addressing jailbreaking attacks (role-playing, authority impersonation, multi-turn manipulation) and privacy extraction attacks. All evaluation utilizes synthetic patient records requiring no IRB approval. The framework is designed to run entirely on consumer CPU hardware using freely available models, eliminating cost barriers. We present the framework specification including threat models, data generation methodology, evaluation protocols, and scoring rubrics. This proposal establishes a foundation for comparative security assessment of medical-specialist models and defense mechanisms, advancing the broader goal of ensuring safe and trustworthy medical AI systems.

Weixuan Chen, Qianqian Yang, Yuanyuan Jia et al.

Semantic communication (SemCom) has emerged as a promising paradigm for future wireless networks by prioritizing task-relevant meaning over raw data delivery, thereby reducing communication overhead and improving efficiency. However, shifting from bit-accurate transmission to task-oriented delivery introduces new security and privacy risks. These include semantic leakage, semantic manipulation, knowledge base vulnerabilities, model-related attacks, and threats to authenticity and availability. Most existing secure SemCom studies focus on analog SemCom, where semantic features are mapped to continuous channel inputs. In contrast, digital SemCom transmits semantic information through discrete bits or symbols within practical transceiver pipelines, offering stronger compatibility with realworld systems while exposing a distinct and underexplored attack surface. In particular, digital SemCom typically represents semantic information over a finite alphabet through explicit digital modulation, following two main routes: probabilistic modulation and deterministic modulation. These discrete mechanisms and practical transmission procedures introduce additional vulnerabilities affecting bit- or symbol-level semantic information, the modulation stage, and packet-based delivery and protocol operations. Motivated by these challenges and the lack of a systematic analysis of secure digital SemCom, this paper provides a structured review of the area. Specifically, we review SemCom fundamentals and clarify the architectural differences between analog and digital SemCom. We then summarize threats shared by both paradigms and organize the threat landscape specific to digital SemCom, followed by a discussion of potential defenses. Finally, we outline open research directions toward secure and deployable digital SemCom systems.

Juntao Li, Haobin Yuan, Ling Luo et al.

Intelligent drug recommendation based on Electronic Health Records (EHRs) is critical for improving for improving the quality and efficiency of clinical decision-making. By leveraging large-scale patient data, drug recommendation systems can assist physicians in selecting the most appropriate medications according to a patient's medical history, diagnoses, laboratory results, and comorbidities. However, the advancement of such systems is significantly hampered by the scarcity of publicly available, real-world EHR datasets, particularly in languages other than English. In this work, we present CDrugRed, a first publicly available Chinese drug recommendation dataset focused on discharge medications for metabolic diseases. The dataset includes 5,894 de-identified records from 3,190 patients, containing comprehensive information such as patient demographics, medical history, clinical course, and discharge diagnoses. We assess the utility of CDrugRed by benchmarking several state-of-the-art large language models (LLMs) on the discharge medication recommendation task. Experimental results show that while supervised fine-tuning improves model performance, there remains substantial room for improvement, with the best model achieving the F1 score of 0.5648 and Jaccard score of 0.4477. This result highlights the complexity of the clinical drug recommendation task and establishes CDrugRed as a challenging and valuable resource for developing more robust and accurate drug recommendation systems. The dataset is publicly available to the research community under the data usage agreements at https://github.com/DUTIR-BioNLP/CDrugRed.

Yajuan Zhang, Jiahai Jiang, Yule Yan et al.

Accurate wind power forecasting can help formulate scientific dispatch plans, which is of great significance for maintaining the safety, stability, and efficient operation of the power system. In recent years, wind power forecasting methods based on deep learning have focused on extracting the spatiotemporal correlations among data, achieving significant improvements in forecasting accuracy. However, they exhibit two limitations. First, there is a lack of modeling for the inter-variable relationships, which limits the accuracy of the forecasts. Second, by treating endogenous and exogenous variables equally, it leads to unnecessary interactions between the endogenous and exogenous variables, increasing the complexity of the model. In this paper, we propose the 2DXformer, which, building upon the previous work's focus on spatiotemporal correlations, addresses the aforementioned two limitations. Specifically, we classify the inputs of the model into three types: exogenous static variables, exogenous dynamic variables, and endogenous variables. First, we embed these variables as variable tokens in a channel-independent manner. Then, we use the attention mechanism to capture the correlations among exogenous variables. Finally, we employ a multi-layer perceptron with residual connections to model the impact of exogenous variables on endogenous variables. Experimental results on two real-world large-scale datasets indicate that our proposed 2DXformer can further improve the performance of wind power forecasting. The code is available in this repository: \href{https://github.com/jseaj/2DXformer}{https://github.com/jseaj/2DXformer}.