Jiacheng Ji

Dongxiao Liu, Yuwen Ding, Xinghai Wei et al.

Applying LLMs to complex industrial processes remains challenging due to the semantic gap between natural language design intents and the rigorous physical logic of engineering. In the field of petroleum refining engineering, a critical bottleneck is the automated synthesis of Unit-level Process Diagrams (UPDs), which serve as the topological bridge connecting abstract requirements to concrete unit operations. In this paper, we propose RefineGPT, a domain-specialized agent for autonomous refinery design.RefineGPT adopts a hierarchical architecture in which a supervised fine-tuned small language model is responsible for selecting units that satisfy design requirements, while a large language model is used to connect these units to generate the final topology. To enable supervised training, we develop a pipeline that extracts latent process motifs from noisy, unstructured legacy topologies and synthesizes high-quality rationale-based Chain-of-Thought (CoT) training data. Empirical validation demonstrates that RefineGPT achieves substantial improvements in topological consistency and chemical engineering feasibility, establishing a high-fidelity pathway for AI-augmented industrial process synthesis.

Haoan Jin, Han Ying, Jiacheng Ji et al.

Recent advances in large language models have enabled their application to a range of healthcare tasks. However, aligning LLMs with the nuanced demands of medical ethics, especially under complex real world scenarios, remains underexplored. In this work, we present MedES, a dynamic, scenario-centric benchmark specifically constructed from 260 authoritative Chinese medical, ethical, and legal sources to reflect the challenges in clinical decision-making. To facilitate model alignment, we introduce a guardian-in-the-loop framework that leverages a dedicated automated evaluator (trained on expert-labeled data and achieving over 97% accuracy within our domain) to generate targeted prompts and provide structured ethical feedback. Using this pipeline, we align a 7B-parameter LLM through supervised fine-tuning and domain-specific preference optimization. Experimental results, conducted entirely within the Chinese medical ethics context, demonstrate that our aligned model outperforms notably larger baselines on core ethical tasks, with observed improvements in both quality and composite evaluation metrics. Our work offers a practical and adaptable framework for aligning LLMs with medical ethics in the Chinese healthcare domain, and suggests that similar alignment pipelines may be instantiated in other legal and cultural environments through modular replacement of the underlying normative corpus.