Abdurrahim Yılmaz

Abdurrahim Yilmaz, Furkan Yuceyalcin, Ece Gokyayla et al.

A major barrier to developing vision large language models (LLMs) in dermatology is the lack of large image--text pairs dataset. We introduce DermaSynth, a dataset comprising of 92,020 synthetic image--text pairs curated from 45,205 images (13,568 clinical and 35,561 dermatoscopic) for dermatology-related clinical tasks. Leveraging state-of-the-art LLMs, using Gemini 2.0, we used clinically related prompts and self-instruct method to generate diverse and rich synthetic texts. Metadata of the datasets were incorporated into the input prompts by targeting to reduce potential hallucinations. The resulting dataset builds upon open access dermatological image repositories (DERM12345, BCN20000, PAD-UFES-20, SCIN, and HIBA) that have permissive CC-BY-4.0 licenses. We also fine-tuned a preliminary Llama-3.2-11B-Vision-Instruct model, DermatoLlama 1.0, on 5,000 samples. We anticipate this dataset to support and accelerate AI research in dermatology. Data and code underlying this work are accessible at https://github.com/abdurrahimyilmaz/DermaSynth.

Abdurrahim Yilmaz, Serra Atilla Aydin, Deniz Temur et al.

Mohs micrographic surgery (MMS) is the gold standard technique for removing high risk nonmelanoma skin cancer however, intraoperative histopathological examination demands significant time, effort, and professionality. The objective of this study is to develop a deep learning model to detect basal cell carcinoma (BCC) and artifacts on Mohs slides. A total of 731 Mohs slides from 51 patients with BCCs were used in this study, with 91 containing tumor and 640 without tumor which was defined as non-tumor. The dataset was employed to train U-Net based models that segment tumor and non-tumor regions on the slides. The segmented patches were classified as tumor, or non-tumor to produce predictions for whole slide images (WSIs). For the segmentation phase, the deep learning model success was measured using a Dice score with 0.70 and 0.67 value, area under the curve (AUC) score with 0.98 and 0.96 for tumor and non-tumor, respectively. For the tumor classification, an AUC of 0.98 for patch-based detection, and AUC of 0.91 for slide-based detection was obtained on the test dataset. We present an AI system that can detect tumors and non-tumors in Mohs slides with high success. Deep learning can aid Mohs surgeons and dermatopathologists in making more accurate decisions.

Abdurrahim Yilmaz, Sirin Pekcan Yasar, Gulsum Gencoglan et al.

Skin lesion datasets provide essential information for understanding various skin conditions and developing effective diagnostic tools. They aid the artificial intelligence-based early detection of skin cancer, facilitate treatment planning, and contribute to medical education and research. Published large datasets have partially coverage the subclassifications of the skin lesions. This limitation highlights the need for more expansive and varied datasets to reduce false predictions and help improve the failure analysis for skin lesions. This study presents a diverse dataset comprising 12,345 dermatoscopic images with 38 subclasses of skin lesions collected in Turkiye which comprises different skin types in the transition zone between Europe and Asia. Each subgroup contains high-resolution photos and expert annotations, providing a strong and reliable basis for future research. The detailed analysis of each subgroup provided in this study facilitates targeted research endeavors and enhances the depth of understanding regarding the skin lesions. This dataset distinguishes itself through a diverse structure with 5 super classes, 15 main classes, 38 subclasses and its 12,345 high-resolution dermatoscopic images.

Abdurrahim Yilmaz, Mucahit Kalebasi, Yegor Samoylenko et al.

Skin cancer is one of the deadly types of cancer and is common in the world. Recently, there has been a huge jump in the rate of people getting skin cancer. For this reason, the number of studies on skin cancer classification with deep learning are increasing day by day. For the growth of work in this area, the International Skin Imaging Collaboration (ISIC) organization was established and they created an open dataset archive. In this study, images were taken from ISIC 2017 Challenge. The skin cancer images taken were preprocessed and data augmented. Later, these images were trained with transfer learning and fine-tuning approach and deep learning models were created in this way. 3 different mobile deep learning models and 3 different batch size values were determined for each, and a total of 9 models were created. Among these models, the NASNetMobile model with 16 batch size got the best result. The accuracy value of this model is 82.00%, the precision value is 81.77% and the F1 score value is 0.8038. Our method is to benchmark mobile deep learning models which have few parameters and compare the results of the models.

Abdurrahim Yilmaz, Ali Anil Demircali, Serra Ozkasap et al.

The purpose of this study is to find ideal forces for reducing cell stress in wound healing process by micro robots. Because of this aim, we made two simulations on COMSOL Multiphysics with micro robot to find correct force. As a result of these simulation, we created force curves to obtain the minimum force and friction force that could lift the cells from the surface will be determined. As the potential of the system for two micro robots that have 2 mm x 0.25 mm x 0.4 mm dimension SU-8 body with 3 NdFeB that have 0.25 thickness and diameter, simulation results at maximum force in the x-axis calculated with 4.640 mN, the distance between the two robots is 150 um.

Abdurrahim Yilmaz, Fatih Goktay, Rahmetullah Varol et al.

The diagnosis of superficial fungal infections in dermatology is still mostly based on manual direct microscopic examination with Potassium Hydroxide (KOH) solution. However, this method can be time consuming and its diagnostic accuracy rates vary widely depending on the clinician's experience. With the increase of neural network applications in the field of clinical microscopy, it is now possible to automate such manual processes increasing both efficiency and accuracy. This study presents a deep neural network structure that enables the rapid solutions for these problems and can perform automatic fungi detection in grayscale images without dyes. 160 microscopic field photographs containing the fungal element, obtained from patients with onychomycosis, and 297 microscopic field photographs containing dissolved keratin obtained from normal nails were collected. Smaller patches containing 4234 fungi and 4981 keratin were extracted from these images. In order to detect fungus and keratin, VGG16 and InceptionV3 models were developed. The VGG16 model had 95.98% accuracy, and the area under the curve (AUC) value of 0.9930, while the InceptionV3 model had 95.90% accuracy and the AUC value of 0.9917. However, average accuracy and AUC value of clinicians is 72.8% and 0.87, respectively. This deep learning model allows the development of an automated system that can detect fungi within microscopic images.

Abdurrahim Yilmaz, Asli Tekeci, Meryem Ece Ozyetkin et al.

This study investigates the effects of porosity on flying creatures such as dragonflies, moths, hummingbirds, etc. wing and shows that pores can affect wing performance. These studies were performed by 3D porous flapping wing flow analyses on Comsol Multiphysics. In this study, we analyzed different numbers of the porous wing at different angles of inclination in order to see the effect of pores on lift and drag forces. To compare the results 9 different analyses were performed. In these analyses, airflow velocity was taken as 5 m/s, angle of attack as 5 degrees, frequency as 25 Hz, and flapping angle as 30 degrees. By keeping these values constant, the number of pores was changed to 36, 48, and 60, and the pore angles of inclination to 60, 70, and 80 degrees. Analyses were carried out by giving laminar flow to this wing designed in the Comsol Multiphysics program. The importance of pores was investigated by comparing the results of these analyses.