Raza Imam

Akshat Sanghvi, Naren Akash, Raza Imam et al.

Large language models (LLMs) are increasingly used for health-related decision support. Yet most evaluations treat diagnosis as a single-shot task with complete information provided upfront, often as a multiple-choice selection. This diverges from clinical practice, where diagnosis is interactive and open-ended, involving sequential hypothesis refinement through targeted questioning. We address this gap. We build MeDxBench, a large-scale benchmark of 4,421 clinical cases across 20 specialties. We further propose MeDxAgent, a multi-agent consultation system for interactive diagnosis, and systematically study its prompt-, flow- and agent-level design choices. MeDxAgent achieves a 10.3% accuracy gain over the baseline on MeDxBench, closing 52.3% of the gap to a full-information oracle. We find that specific design choices: collecting demographics first, passing summarized dialogue for diagnosis, and feeding candidate diagnoses for targeted questioning, improve accuracy, mirroring how physicians reason, though their effect emerges fully only in combination. Code and dataset will be released upon publication.

Qazi Mohammad Areeb, Mohammad Nadeem, Shahab Saquib Sohail et al.

A filter bubble refers to the phenomenon where Internet customization effectively isolates individuals from diverse opinions or materials, resulting in their exposure to only a select set of content. This can lead to the reinforcement of existing attitudes, beliefs, or conditions. In this study, our primary focus is to investigate the impact of filter bubbles in recommender systems. This pioneering research aims to uncover the reasons behind this problem, explore potential solutions, and propose an integrated tool to help users avoid filter bubbles in recommender systems. To achieve this objective, we conduct a systematic literature review on the topic of filter bubbles in recommender systems. The reviewed articles are carefully analyzed and classified, providing valuable insights that inform the development of an integrated approach. Notably, our review reveals evidence of filter bubbles in recommendation systems, highlighting several biases that contribute to their existence. Moreover, we propose mechanisms to mitigate the impact of filter bubbles and demonstrate that incorporating diversity into recommendations can potentially help alleviate this issue. The findings of this timely review will serve as a benchmark for researchers working in interdisciplinary fields such as privacy, artificial intelligence ethics, and recommendation systems. Furthermore, it will open new avenues for future research in related domains, prompting further exploration and advancement in this critical area.

Umaima Rahman, Raza Imam, Mohammad Yaqub et al.

In medical image classification, supervised learning is challenging due to the scarcity of labeled medical images. To address this, we leverage the visual-textual alignment within Vision-Language Models (VLMs) to enable unsupervised learning of a medical image classifier. In this work, we propose \underline{Med}ical \underline{Un}supervised \underline{A}daptation (\texttt{MedUnA}) of VLMs, where the LLM-generated descriptions for each class are encoded into text embeddings and matched with class labels via a cross-modal adapter. This adapter attaches to a visual encoder of \texttt{MedCLIP} and aligns the visual embeddings through unsupervised learning, driven by a contrastive entropy-based loss and prompt tuning. Thereby, improving performance in scenarios where textual information is more abundant than labeled images, particularly in the healthcare domain. Unlike traditional VLMs, \texttt{MedUnA} uses \textbf{unpaired images and text} for learning representations and enhances the potential of VLMs beyond traditional constraints. We evaluate the performance on three chest X-ray datasets and two multi-class datasets (diabetic retinopathy and skin lesions), showing significant accuracy gains over the zero-shot baseline. Our code is available at https://github.com/rumaima/meduna.

Raza Imam, Hanan Gani, Muhammad Huzaifa et al.

The conventional modus operandi for adapting pre-trained vision-language models (VLMs) during test-time involves tuning learnable prompts, ie, test-time prompt tuning. This paper introduces Test-Time Low-rank adaptation (TTL) as an alternative to prompt tuning for zero-shot generalization of large-scale VLMs. Taking inspiration from recent advancements in efficiently fine-tuning large language models, TTL offers a test-time parameter-efficient adaptation approach that updates the attention weights of the transformer encoder by maximizing prediction confidence. The self-supervised confidence maximization objective is specified using a weighted entropy loss that enforces consistency among predictions of augmented samples. TTL introduces only a small amount of trainable parameters for low-rank adapters in the model space while keeping the prompts and backbone frozen. Extensive experiments on a variety of natural distribution and cross-domain tasks show that TTL can outperform other techniques for test-time optimization of VLMs in strict zero-shot settings. Specifically, TTL outperforms test-time prompt tuning baselines with a significant improvement on average. Our code is available at at https://github.com/Razaimam45/TTL-Test-Time-Low-Rank-Adaptation.

Darakshan Rashid, Raza Imam, Dwarikanath Mahapatra et al.

Deep neural networks for chest X-ray classification achieve strong average performance, yet often underperform for specific demographic subgroups, raising critical concerns about clinical safety and equity. Existing debiasing methods frequently yield inconsistent improvements across datasets or attain fairness by degrading overall diagnostic utility, treating fairness as a post hoc constraint rather than a property of the learned representation. In this work, we propose Stride-Net (Sensitive Attribute Resilient Learning via Disentanglement and Learnable Masking with Embedding Alignment), a fairness-aware framework that learns disease-discriminative yet demographically invariant representations for chest X-ray analysis. Stride-Net operates at the patch level, using a learnable stride-based mask to select label-aligned image regions while suppressing sensitive attribute information through adversarial confusion loss. To anchor representations in clinical semantics and discourage shortcut learning, we further enforce semantic alignment between image features and BioBERT-based disease label embeddings via Group Optimal Transport. We evaluate Stride-Net on the MIMIC-CXR and CheXpert benchmarks across race and intersectional race-gender subgroups. Across architectures including ResNet and Vision Transformers, Stride-Net consistently improves fairness metrics while matching or exceeding baseline accuracy, achieving a more favorable accuracy-fairness trade-off than prior debiasing approaches. Our code is available at https://github.com/Daraksh/Fairness_StrideNet.

Raza Imam, Ibrahim Almakky, Salma Alrashdi et al.

Deep Learning methods have recently seen increased adoption in medical imaging applications. However, elevated vulnerabilities have been explored in recent Deep Learning solutions, which can hinder future adoption. Particularly, the vulnerability of Vision Transformer (ViT) to adversarial, privacy, and confidentiality attacks raise serious concerns about their reliability in medical settings. This work aims to enhance the robustness of self-ensembling ViTs for the tuberculosis chest x-ray classification task. We propose Self-Ensembling ViT with defensive Distillation and Adversarial training (SEDA). SEDA utilizes efficient CNN blocks to learn spatial features with various levels of abstraction from feature representations extracted from intermediate ViT blocks, that are largely unaffected by adversarial perturbations. Furthermore, SEDA leverages adversarial training in combination with defensive distillation for improved robustness against adversaries. Training using adversarial examples leads to better model generalizability and improves its ability to handle perturbations. Distillation using soft probabilities introduces uncertainty and variation into the output probabilities, making it more difficult for adversarial and privacy attacks. Extensive experiments performed with the proposed architecture and training paradigm on publicly available Tuberculosis x-ray dataset shows SOTA efficacy of SEDA compared to SEViT in terms of computational efficiency with 70x times lighter framework and enhanced robustness of +9%.

Raza Imam, Hu Wang, Dwarikanath Mahapatra et al.

In medical imaging, vision-language models face a critical duality: pretrained networks offer broad robustness but lack subtle, modality-specific characteristics, while fine-tuned expert models achieve high in-distribution accuracy yet falter under modality shift. Existing model-merging techniques, designed for natural-image benchmarks, are simple and efficient but fail to deliver consistent gains across diverse medical modalities; their static interpolation limits reliability in varied clinical tasks. To address this, we introduce Test-Time Task adaptive merging (T^3), a backpropagation-free framework that computes per-sample interpolation coefficients via the Jensen-Shannon divergence between the two models' output distributions. T^3 dynamically preserves local precision when models agree and defers to generalist robustness under drift. To overcome the inference costs of sample-wise merging, we further propose a batch-wise extension, T^3_B, that computes a merging coefficient across a batch of samples, dramatically reducing computational bottleneck. Recognizing the lack of a standardized medical-merging benchmark, we present a rigorous cross-evaluation protocol spanning in-domain, base-to-novel, and corruptions across four modalities. Empirically, T^3 sets new state-of-the-art in Top-1 accuracy and error reduction, outperforming strong baselines while maintaining efficiency, paving the way for adaptive MVLM deployment in clinical settings. Our code is available at https://github.com/Razaimam45/TCube.

Raza Imam, Mohammed Talha Alam, Umaima Rahman et al.

Existing vision-text contrastive learning models enhance representation transferability and support zero-shot prediction by matching paired image and caption embeddings while pushing unrelated pairs apart. However, astronomical image-label datasets are significantly smaller compared to general image and label datasets available from the internet. We introduce CosmoCLIP, an astronomical image-text contrastive learning framework precisely fine-tuned on the pre-trained CLIP model using SpaceNet and BLIP-based captions. SpaceNet, attained via FLARE, constitutes ~13k optimally distributed images, while BLIP acts as a rich knowledge extractor. The rich semantics derived from this SpaceNet and BLIP descriptions, when learned contrastively, enable CosmoCLIP to achieve superior generalization across various in-domain and out-of-domain tasks. Our results demonstrate that CosmoCLIP is a straightforward yet powerful framework, significantly outperforming CLIP in zero-shot classification and image-text retrieval tasks.

Raza Imam, Mohammed Talha Alam

Deep learning has emerged as a prominent field in recent literature, showcasing the introduction of models that utilize transfer learning to achieve remarkable accuracies in the classification of brain tumor MRI images. However, the majority of these proposals primarily focus on balanced datasets, neglecting the inherent data imbalance present in real-world scenarios. Consequently, there is a pressing need for approaches that not only address the data imbalance but also prioritize precise classification of brain cancer. In this work, we present a novel deep learning-based approach, called Transfer Learning-CNN, for brain tumor classification using MRI data. The proposed model leverages the predictive capabilities of existing publicly available models by utilizing their pre-trained weights and transferring those weights to the CNN. By leveraging a publicly available Brain MRI dataset, the experiment evaluated various transfer learning models for classifying different tumor types, including meningioma, glioma, and pituitary tumors. We investigate the impact of different loss functions, including focal loss, and oversampling methods, such as SMOTE and ADASYN, in addressing the data imbalance issue. Notably, the proposed strategy, which combines VGG-16 and CNN, achieved an impressive accuracy rate of 96%, surpassing alternative approaches significantly.

Mohammed Talha Alam, Raza Imam, Mohsen Guizani et al.

The prevalence of AI-generated imagery has raised concerns about the authenticity of astronomical images, especially with advanced text-to-image models like Stable Diffusion producing highly realistic synthetic samples. Existing detection methods, primarily based on convolutional neural networks (CNNs) or spectral analysis, have limitations when used independently. We present AstroSpy, a hybrid model that integrates both spectral and image features to distinguish real from synthetic astronomical images. Trained on a unique dataset of real NASA images and AI-generated fakes (approximately 18k samples), AstroSpy utilizes a dual-pathway architecture to fuse spatial and spectral information. This approach enables AstroSpy to achieve superior performance in identifying authentic astronomical images. Extensive evaluations demonstrate AstroSpy's effectiveness and robustness, significantly outperforming baseline models in both in-domain and cross-domain tasks, highlighting its potential to combat misinformation in astronomy.

Mohammed Talha Alam, Raza Imam, Mohsen Guizani et al.

The intersection of Astronomy and AI encounters significant challenges related to issues such as noisy backgrounds, lower resolution (LR), and the intricate process of filtering and archiving images from advanced telescopes like the James Webb. Given the dispersion of raw images in feature space, we have proposed a \textit{two-stage augmentation framework} entitled as \textbf{FLARE} based on \underline{f}eature \underline{l}earning and \underline{a}ugmented \underline{r}esolution \underline{e}nhancement. We first apply lower (LR) to higher resolution (HR) conversion followed by standard augmentations. Secondly, we integrate a diffusion approach to synthetically generate samples using class-concatenated prompts. By merging these two stages using weighted percentiles, we realign the feature space distribution, enabling a classification model to establish a distinct decision boundary and achieve superior generalization on various in-domain and out-of-domain tasks. We conducted experiments on several downstream cosmos datasets and on our optimally distributed \textbf{SpaceNet} dataset across 8-class fine-grained and 4-class macro classification tasks. FLARE attains the highest performance gain of 20.78\% for fine-grained tasks compared to similar baselines, while across different classification models, FLARE shows a consistent increment of an average of +15\%. This outcome underscores the effectiveness of the FLARE method in enhancing the precision of image classification, ultimately bolstering the reliability of astronomical research outcomes. % Our code and SpaceNet dataset will be released to the public soon. Our code and SpaceNet dataset is available at \href{https://github.com/Razaimam45/PlanetX_Dxb}{\textit{https://github.com/Razaimam45/PlanetX\_Dxb}}.

Mohammed Talha Alam, Raza Imam, Mohammad Areeb Qazi et al.

Advancements in generative modeling are pushing the state-of-the-art in synthetic medical image generation. These synthetic images can serve as an effective data augmentation method to aid the development of more accurate machine learning models for medical image analysis. While the fidelity of these synthetic images has progressively increased, the diversity of these images is an understudied phenomenon. In this work, we propose the SDICE index, which is based on the characterization of similarity distributions induced by a contrastive encoder. Given a synthetic dataset and a reference dataset of real images, the SDICE index measures the distance between the similarity score distributions of original and synthetic images, where the similarity scores are estimated using a pre-trained contrastive encoder. This distance is then normalized using an exponential function to provide a consistent metric that can be easily compared across domains. Experiments conducted on the MIMIC-chest X-ray and ImageNet datasets demonstrate the effectiveness of SDICE index in assessing synthetic medical dataset diversity.

Raza Imam, Muhammad Huzaifa, Nabil Mansour et al.

In this study, we propose an automated framework for camel farm monitoring, introducing two key contributions: the Unified Auto-Annotation framework and the Fine-Tune Distillation framework. The Unified Auto-Annotation approach combines two models, GroundingDINO (GD), and Segment-Anything-Model (SAM), to automatically annotate raw datasets extracted from surveillance videos. Building upon this foundation, the Fine-Tune Distillation framework conducts fine-tuning of student models using the auto-annotated dataset. This process involves transferring knowledge from a large teacher model to a student model, resembling a variant of Knowledge Distillation. The Fine-Tune Distillation framework aims to be adaptable to specific use cases, enabling the transfer of knowledge from the large models to the small models, making it suitable for domain-specific applications. By leveraging our raw dataset collected from Al-Marmoom Camel Farm in Dubai, UAE, and a pre-trained teacher model, GroundingDINO, the Fine-Tune Distillation framework produces a lightweight deployable model, YOLOv8. This framework demonstrates high performance and computational efficiency, facilitating efficient real-time object detection. Our code is available at \href{https://github.com/Razaimam45/Fine-Tune-Distillation}{https://github.com/Razaimam45/Fine-Tune-Distillation}

Umaima Rahman, Raza Imam, Mohammad Yaqub et al.

Medical vision-language models (VLMs) offer promise for clinical decision support, yet their reliability under distribution shifts remains a major concern for safe deployment. These models often learn task-agnostic correlations due to variability in imaging protocols and free-text reports, limiting their generalizability and increasing the risk of failure in real-world settings. We propose DRiFt, a structured feature decoupling framework that explicitly separates clinically relevant signals from task-agnostic noise using parameter-efficient tuning (LoRA) and learnable prompt tokens. To enhance cross-modal alignment and reduce uncertainty, we curate high-quality, clinically grounded image-text pairs by generating captions for a diverse medical dataset. Our approach improves in-distribution performance by +11.4% Top-1 accuracy and +3.3% Macro-F1 over prior prompt-based methods, while maintaining strong robustness across unseen datasets. Ablation studies reveal that disentangling task-relevant features and careful alignment significantly enhance model generalization and reduce unpredictable behavior under domain shift. These insights contribute toward building safer, more trustworthy VLMs for clinical use. The code is available at https://github.com/rumaima/DRiFt.

Mohammad Amaan Sayeed, Mohammed Talha Alam, Raza Imam et al.

Centuries-old Islamic medical texts like Avicenna's Canon of Medicine and the Prophetic Tibb-e-Nabawi encode a wealth of preventive care, nutrition, and holistic therapies, yet remain inaccessible to many and underutilized in modern AI systems. Existing language-model benchmarks focus narrowly on factual recall or user preference, leaving a gap in validating culturally grounded medical guidance at scale. We propose a unified evaluation pipeline, Tibbe-AG, that aligns 30 carefully curated Prophetic-medicine questions with human-verified remedies and compares three LLMs (LLaMA-3, Mistral-7B, Qwen2-7B) under three configurations: direct generation, retrieval-augmented generation, and a scientific self-critique filter. Each answer is then assessed by a secondary LLM serving as an agentic judge, yielding a single 3C3H quality score. Retrieval improves factual accuracy by 13%, while the agentic prompt adds another 10% improvement through deeper mechanistic insight and safety considerations. Our results demonstrate that blending classical Islamic texts with retrieval and self-evaluation enables reliable, culturally sensitive medical question-answering.

Raza Imam, Rufael Marew, Mohammad Yaqub

Medical Vision-Language Models (MVLMs) have achieved par excellence generalization in medical image analysis, yet their performance under noisy, corrupted conditions remains largely untested. Clinical imaging is inherently susceptible to acquisition artifacts and noise; however, existing evaluations predominantly assess generally clean datasets, overlooking robustness -- i.e., the model's ability to perform under real-world distortions. To address this gap, we first introduce MediMeta-C, a corruption benchmark that systematically applies several perturbations across multiple medical imaging datasets. Combined with MedMNIST-C, this establishes a comprehensive robustness evaluation framework for MVLMs. We further propose RobustMedCLIP, a visual encoder adaptation of a pretrained MVLM that incorporates few-shot tuning to enhance resilience against corruptions. Through extensive experiments, we benchmark 5 major MVLMs across 5 medical imaging modalities, revealing that existing models exhibit severe degradation under corruption and struggle with domain-modality tradeoffs. Our findings highlight the necessity of diverse training and robust adaptation strategies, demonstrating that efficient low-rank adaptation when paired with few-shot tuning, improves robustness while preserving generalization across modalities.

Raza Imam, Asif Hanif, Jian Zhang et al.

Recently, test-time adaptation has garnered attention as a method for tuning models without labeled data. The conventional modus operandi for adapting pre-trained vision-language models (VLMs) during test-time primarily focuses on tuning learnable prompts; however, this approach overlooks potential distribution shifts in the visual representations themselves. In this work, we address this limitation by introducing Test-Time Noise Tuning (TNT), a novel method for handling unpredictable shifts in the visual space. TNT leverages, for the first time, a noise adaptation strategy that optimizes learnable noise directly in the visual input space, enabling adaptive feature learning from a single test sample. We further introduce a novel approach for inter-view representation alignment by explicitly enforcing coherence in embedding distances, ensuring consistent feature representations across views. Combined with scaled logits and confident view selection at inference, TNT substantially enhances VLM generalization and calibration, achieving average gains of +7.38% on natural distributions benchmark and +0.80% on cross-dataset evaluations over zero-shot CLIP. These improvements lay a strong foundation for adaptive out-of-distribution handling.

Maryam Nadeem, Raza Imam, Rouqaiah Al-Refai et al.

As virtual environments continue to advance, the demand for immersive and emotionally engaging experiences has grown. Addressing this demand, we introduce Emotion enabled Virtual avatar mapping using Optimized KnowledgE distillation (EVOKE), a lightweight emotion recognition framework designed for the seamless integration of emotion recognition into 3D avatars within virtual environments. Our approach leverages knowledge distillation involving multi-label classification on the publicly available DEAP dataset, which covers valence, arousal, and dominance as primary emotional classes. Remarkably, our distilled model, a CNN with only two convolutional layers and 18 times fewer parameters than the teacher model, achieves competitive results, boasting an accuracy of 87% while demanding far less computational resources. This equilibrium between performance and deployability positions our framework as an ideal choice for virtual environment systems. Furthermore, the multi-label classification outcomes are utilized to map emotions onto custom-designed 3D avatars.

Raza Imam, Muhammad Huzaifa, Mohammed El-Amine Azz

Privacy and confidentiality of medical data are of utmost importance in healthcare settings. ViTs, the SOTA vision model, rely on large amounts of patient data for training, which raises concerns about data security and the potential for unauthorized access. Adversaries may exploit vulnerabilities in ViTs to extract sensitive patient information and compromising patient privacy. This work address these vulnerabilities to ensure the trustworthiness and reliability of ViTs in medical applications. In this work, we introduced a defensive diffusion technique as an adversarial purifier to eliminate adversarial noise introduced by attackers in the original image. By utilizing the denoising capabilities of the diffusion model, we employ a reverse diffusion process to effectively eliminate the adversarial noise from the attack sample, resulting in a cleaner image that is then fed into the ViT blocks. Our findings demonstrate the effectiveness of the diffusion model in eliminating attack-agnostic adversarial noise from images. Additionally, we propose combining knowledge distillation with our framework to obtain a lightweight student model that is both computationally efficient and robust against gray box attacks. Comparison of our method with a SOTA baseline method, SEViT, shows that our work is able to outperform the baseline. Extensive experiments conducted on a publicly available Tuberculosis X-ray dataset validate the computational efficiency and improved robustness achieved by our proposed architecture.