Minghui Li

Shengshan Hu, Junwei Zhang, Wei Liu et al.

Point cloud completion, as the upstream procedure of 3D recognition and segmentation, has become an essential part of many tasks such as navigation and scene understanding. While various point cloud completion models have demonstrated their powerful capabilities, their robustness against adversarial attacks, which have been proven to be fatally malicious towards deep neural networks, remains unknown. In addition, existing attack approaches towards point cloud classifiers cannot be applied to the completion models due to different output forms and attack purposes. In order to evaluate the robustness of the completion models, we propose PointCA, the first adversarial attack against 3D point cloud completion models. PointCA can generate adversarial point clouds that maintain high similarity with the original ones, while being completed as another object with totally different semantic information. Specifically, we minimize the representation discrepancy between the adversarial example and the target point set to jointly explore the adversarial point clouds in the geometry space and the feature space. Furthermore, to launch a stealthier attack, we innovatively employ the neighbourhood density information to tailor the perturbation constraint, leading to geometry-aware and distribution-adaptive modifications for each point. Extensive experiments against different premier point cloud completion networks show that PointCA can cause a performance degradation from 77.9% to 16.7%, with the structure chamfer distance kept below 0.01. We conclude that existing completion models are severely vulnerable to adversarial examples, and state-of-the-art defenses for point cloud classification will be partially invalid when applied to incomplete and uneven point cloud data.

Xiaogeng Liu, Minghui Li, Haoyu Wang et al.

Deep neural networks are proven to be vulnerable to backdoor attacks. Detecting the trigger samples during the inference stage, i.e., the test-time trigger sample detection, can prevent the backdoor from being triggered. However, existing detection methods often require the defenders to have high accessibility to victim models, extra clean data, or knowledge about the appearance of backdoor triggers, limiting their practicality. In this paper, we propose the test-time corruption robustness consistency evaluation (TeCo), a novel test-time trigger sample detection method that only needs the hard-label outputs of the victim models without any extra information. Our journey begins with the intriguing observation that the backdoor-infected models have similar performance across different image corruptions for the clean images, but perform discrepantly for the trigger samples. Based on this phenomenon, we design TeCo to evaluate test-time robustness consistency by calculating the deviation of severity that leads to predictions' transition across different corruptions. Extensive experiments demonstrate that compared with state-of-the-art defenses, which even require either certain information about the trigger types or accessibility of clean data, TeCo outperforms them on different backdoor attacks, datasets, and model architectures, enjoying a higher AUROC by 10% and 5 times of stability.

Shengshan Hu, Xiaogeng Liu, Yechao Zhang et al.

While deep face recognition (FR) systems have shown amazing performance in identification and verification, they also arouse privacy concerns for their excessive surveillance on users, especially for public face images widely spread on social networks. Recently, some studies adopt adversarial examples to protect photos from being identified by unauthorized face recognition systems. However, existing methods of generating adversarial face images suffer from many limitations, such as awkward visual, white-box setting, weak transferability, making them difficult to be applied to protect face privacy in reality. In this paper, we propose adversarial makeup transfer GAN (AMT-GAN), a novel face protection method aiming at constructing adversarial face images that preserve stronger black-box transferability and better visual quality simultaneously. AMT-GAN leverages generative adversarial networks (GAN) to synthesize adversarial face images with makeup transferred from reference images. In particular, we introduce a new regularization module along with a joint training strategy to reconcile the conflicts between the adversarial noises and the cycle consistence loss in makeup transfer, achieving a desirable balance between the attack strength and visual changes. Extensive experiments verify that compared with state of the arts, AMT-GAN can not only preserve a comfortable visual quality, but also achieve a higher attack success rate over commercial FR APIs, including Face++, Aliyun, and Microsoft.

Ziqi Zhou, Shengshan Hu, Minghui Li et al.

Multimodal contrastive learning aims to train a general-purpose feature extractor, such as CLIP, on vast amounts of raw, unlabeled paired image-text data. This can greatly benefit various complex downstream tasks, including cross-modal image-text retrieval and image classification. Despite its promising prospect, the security issue of cross-modal pre-trained encoder has not been fully explored yet, especially when the pre-trained encoder is publicly available for commercial use. In this work, we propose AdvCLIP, the first attack framework for generating downstream-agnostic adversarial examples based on cross-modal pre-trained encoders. AdvCLIP aims to construct a universal adversarial patch for a set of natural images that can fool all the downstream tasks inheriting the victim cross-modal pre-trained encoder. To address the challenges of heterogeneity between different modalities and unknown downstream tasks, we first build a topological graph structure to capture the relevant positions between target samples and their neighbors. Then, we design a topology-deviation based generative adversarial network to generate a universal adversarial patch. By adding the patch to images, we minimize their embeddings similarity to different modality and perturb the sample distribution in the feature space, achieving unviersal non-targeted attacks. Our results demonstrate the excellent attack performance of AdvCLIP on two types of downstream tasks across eight datasets. We also tailor three popular defenses to mitigate AdvCLIP, highlighting the need for new defense mechanisms to defend cross-modal pre-trained encoders.

Yining Hua, Jiageng Wu, Shixu Lin et al.

Objective: Social media-based public health research is crucial for epidemic surveillance, but most studies identify relevant corpora with keyword-matching. This study develops a system to streamline the process of curating colloquial medical dictionaries. We demonstrate the pipeline by curating a UMLS-colloquial symptom dictionary from COVID-19-related tweets as proof of concept. Methods: COVID-19-related tweets from February 1, 2020, to April 30, 2022 were used. The pipeline includes three modules: a named entity recognition module to detect symptoms in tweets; an entity normalization module to aggregate detected entities; and a mapping module that iteratively maps entities to Unified Medical Language System concepts. A random 500 entity sample were drawn from the final dictionary for accuracy validation. Additionally, we conducted a symptom frequency distribution analysis to compare our dictionary to a pre-defined lexicon from previous research. Results: We identified 498,480 unique symptom entity expressions from the tweets. Pre-processing reduces the number to 18,226. The final dictionary contains 38,175 unique expressions of symptoms that can be mapped to 966 UMLS concepts (accuracy = 95%). Symptom distribution analysis found that our dictionary detects more symptoms and is effective at identifying psychiatric disorders like anxiety and depression, often missed by pre-defined lexicons. Conclusions: This study advances public health research by implementing a novel, systematic pipeline for curating symptom lexicons from social media data. The final lexicon's high accuracy, validated by medical professionals, underscores the potential of this methodology to reliably interpret and categorize vast amounts of unstructured social media data into actionable medical insights across diverse linguistic and regional landscapes.

Yechao Zhang, Shengshan Hu, Leo Yu Zhang et al.

Adversarial examples (AEs) for DNNs have been shown to be transferable: AEs that successfully fool white-box surrogate models can also deceive other black-box models with different architectures. Although a bunch of empirical studies have provided guidance on generating highly transferable AEs, many of these findings lack explanations and even lead to inconsistent advice. In this paper, we take a further step towards understanding adversarial transferability, with a particular focus on surrogate aspects. Starting from the intriguing little robustness phenomenon, where models adversarially trained with mildly perturbed adversarial samples can serve as better surrogates, we attribute it to a trade-off between two predominant factors: model smoothness and gradient similarity. Our investigations focus on their joint effects, rather than their separate correlations with transferability. Through a series of theoretical and empirical analyses, we conjecture that the data distribution shift in adversarial training explains the degradation of gradient similarity. Building on these insights, we explore the impacts of data augmentation and gradient regularization on transferability and identify that the trade-off generally exists in the various training mechanisms, thus building a comprehensive blueprint for the regulation mechanism behind transferability. Finally, we provide a general route for constructing better surrogates to boost transferability which optimizes both model smoothness and gradient similarity simultaneously, e.g., the combination of input gradient regularization and sharpness-aware minimization (SAM), validated by extensive experiments. In summary, we call for attention to the united impacts of these two factors for launching effective transfer attacks, rather than optimizing one while ignoring the other, and emphasize the crucial role of manipulating surrogate models.

Hangtao Zhang, Chenyu Zhu, Xianlong Wang et al.

Embodied AI represents systems where AI is integrated into physical entities. Large Language Model (LLM), which exhibits powerful language understanding abilities, has been extensively employed in embodied AI by facilitating sophisticated task planning. However, a critical safety issue remains overlooked: could these embodied LLMs perpetrate harmful behaviors? In response, we introduce BadRobot, a novel attack paradigm aiming to make embodied LLMs violate safety and ethical constraints through typical voice-based user-system interactions. Specifically, three vulnerabilities are exploited to achieve this type of attack: (i) manipulation of LLMs within robotic systems, (ii) misalignment between linguistic outputs and physical actions, and (iii) unintentional hazardous behaviors caused by world knowledge's flaws. Furthermore, we construct a benchmark of various malicious physical action queries to evaluate BadRobot's attack performance. Based on this benchmark, extensive experiments against existing prominent embodied LLM frameworks (e.g., Voxposer, Code as Policies, and ProgPrompt) demonstrate the effectiveness of our BadRobot.

Ziqi Zhou, Yufei Song, Minghui Li et al.

Segment Anything Model (SAM) has recently gained much attention for its outstanding generalization to unseen data and tasks. Despite its promising prospect, the vulnerabilities of SAM, especially to universal adversarial perturbation (UAP) have not been thoroughly investigated yet. In this paper, we propose DarkSAM, the first prompt-free universal attack framework against SAM, including a semantic decoupling-based spatial attack and a texture distortion-based frequency attack. We first divide the output of SAM into foreground and background. Then, we design a shadow target strategy to obtain the semantic blueprint of the image as the attack target. DarkSAM is dedicated to fooling SAM by extracting and destroying crucial object features from images in both spatial and frequency domains. In the spatial domain, we disrupt the semantics of both the foreground and background in the image to confuse SAM. In the frequency domain, we further enhance the attack effectiveness by distorting the high-frequency components (i.e., texture information) of the image. Consequently, with a single UAP, DarkSAM renders SAM incapable of segmenting objects across diverse images with varying prompts. Experimental results on four datasets for SAM and its two variant models demonstrate the powerful attack capability and transferability of DarkSAM.

Xianlong Wang, Hewen Pan, Hangtao Zhang et al.

Robotic manipulation policies are increasingly empowered by \textit{large language models} (LLMs) and \textit{vision-language models} (VLMs), leveraging their understanding and perception capabilities. Recently, inference-time attacks against robotic manipulation have been extensively studied, yet backdoor attacks targeting model supply chain security in robotic policies remain largely unexplored. To fill this gap, we propose \texttt{TrojanRobot}, a backdoor injection framework for model supply chain attack scenarios, which embeds a malicious module into modular robotic policies via backdoor relationships to manipulate the LLM-to-VLM pathway and compromise the system. Our vanilla design instantiates this module as a backdoor-finetuned VLM. To further enhance attack performance, we propose a prime scheme by introducing the concept of \textit{LVLM-as-a-backdoor}, which leverages \textit{in-context instruction learning} (ICIL) to steer \textit{large vision-language model} (LVLM) behavior through backdoored system prompts. Moreover, we develop three types of prime attacks, \textit{permutation}, \textit{stagnation}, and \textit{intentional}, achieving flexible backdoor attack effects. Extensive physical-world and simulator experiments on 18 real-world manipulation tasks and 4 VLMs verify the superiority of proposed \texttt{TrojanRobot}

Minghui Li, Jiangxiong Wang, Hao Zhang et al.

The success of deep face recognition (FR) systems has raised serious privacy concerns due to their ability to enable unauthorized tracking of users in the digital world. Previous studies proposed introducing imperceptible adversarial noises into face images to deceive those face recognition models, thus achieving the goal of enhancing facial privacy protection. Nevertheless, they heavily rely on user-chosen references to guide the generation of adversarial noises, and cannot simultaneously construct natural and highly transferable adversarial face images in black-box scenarios. In light of this, we present a novel face privacy protection scheme with improved transferability while maintain high visual quality. We propose shaping the entire face space directly instead of exploiting one kind of facial characteristic like makeup information to integrate adversarial noises. To achieve this goal, we first exploit global adversarial latent search to traverse the latent space of the generative model, thereby creating natural adversarial face images with high transferability. We then introduce a key landmark regularization module to preserve the visual identity information. Finally, we investigate the impacts of various kinds of latent spaces and find that $\mathcal{F}$ latent space benefits the trade-off between visual naturalness and adversarial transferability. Extensive experiments over two datasets demonstrate that our approach significantly enhances attack transferability while maintaining high visual quality, outperforming state-of-the-art methods by an average 25% improvement in deep FR models and 10% improvement on commercial FR APIs, including Face++, Aliyun, and Tencent.

Yufei Song, Ziqi Zhou, Menghao Deng et al.

Existing segmentation models exhibit significant vulnerability to adversarial attacks.To improve robustness, adversarial training incorporates adversarial examples into model training. However, existing attack methods consider only global semantic information and ignore contextual semantic relationships within the samples, limiting the effectiveness of adversarial training. To address this issue, we propose EroSeg-AT, a vulnerability-aware adversarial training framework that leverages EroSeg to generate adversarial examples. EroSeg first selects sensitive pixels based on pixel-level confidence and then progressively propagates perturbations to higher-confidence pixels, effectively disrupting the semantic consistency of the samples. Experimental results show that, compared to existing methods, our approach significantly improves attack effectiveness and enhances model robustness under adversarial training.

Lulu Xue, Shengshan Hu, Wei Lu et al.

Machine unlearning is an emerging technique that aims to remove the influence of specific data from trained models, thereby enhancing privacy protection. However, recent research has uncovered critical privacy vulnerabilities, showing that adversaries can exploit unlearning inversion to reconstruct data that was intended to be erased. Despite the severity of this threat, dedicated defenses remain lacking. To address this gap, we propose UnlearnShield, the first defense specifically tailored to counter unlearning inversion. UnlearnShield introduces directional perturbations in the cosine representation space and regulates them through a constraint module to jointly preserve model accuracy and forgetting efficacy, thereby reducing inversion risk while maintaining utility. Experiments demonstrate that it achieves a good trade-off among privacy protection, accuracy, and forgetting.

Lulu Xue, Shengshan Hu, Linqiang Qian et al.

Machine unlearning is a newly popularized technique for removing specific training data from a trained model, enabling it to comply with data deletion requests. While it protects the rights of users requesting unlearning, it also introduces new privacy risks. Prior works have primarily focused on the privacy of data that has been unlearned, while the risks to retained data remain largely unexplored. To address this gap, we focus on the privacy risks of retained data and, for the first time, reveal the vulnerabilities introduced by machine unlearning under the dual-view setting, where an adversary can query both the original and the unlearned models. From an information-theoretic perspective, we introduce the concept of {privacy knowledge gain} and demonstrate that the dual-view setting allows adversaries to obtain more information than querying either model alone, thereby amplifying privacy leakage. To effectively demonstrate this threat, we propose DVIA, a Dual-View Inference Attack, which extracts membership information on retained data using black-box queries to both models. DVIA eliminates the need to train an attack model and employs a lightweight likelihood ratio inference module for efficient inference. Experiments across different datasets and model architectures validate the effectiveness of DVIA and highlight the privacy risks inherent in the dual-view setting.

Minghui Li, Xianlong Wang, Zhifei Yu et al.

Convolution-based unlearnable examples (UEs) employ class-wise multiplicative convolutional noise to training samples, severely compromising model performance. This fire-new type of UEs have successfully countered all defense mechanisms against UEs. The failure of such defenses can be attributed to the absence of norm constraints on convolutional noise, leading to severe blurring of image features. To address this, we first design an Edge Pixel-based Detector (EPD) to identify convolution-based UEs. Upon detection of them, we propose the first defense scheme against convolution-based UEs, COrrupting these samples via random matrix multiplication by employing bilinear INterpolation (COIN) such that disrupting the distribution of class-wise multiplicative noise. To evaluate the generalization of our proposed COIN, we newly design two convolution-based UEs called VUDA and HUDA to expand the scope of convolution-based UEs. Extensive experiments demonstrate the effectiveness of detection scheme EPD and that our defense COIN outperforms 11 state-of-the-art (SOTA) defenses, achieving a significant improvement on the CIFAR and ImageNet datasets.

Hewen Pan, Cong Wei, Dashuang Liang et al.

With the advancement of multi-modal Large Language Models (LLMs), Video LLMs have been further developed to perform on holistic and specialized video understanding. However, existing works are limited to specialized video understanding tasks, failing to achieve a comprehensive and multi-grained video perception. To bridge this gap, we introduce UFVideo, the first Video LLM with unified multi-grained cooperative understanding capabilities. Specifically, we design unified visual-language guided alignment to flexibly handle video understanding across global, pixel and temporal scales within a single model. UFVideo dynamically encodes the visual and text inputs of different tasks and generates the textual response, temporal localization, or grounded mask. Additionally, to evaluate challenging multi-grained video understanding tasks, we construct the UFVideo-Bench consisting of three distinct collaborative tasks within the scales, which demonstrates UFVideo's flexibility and advantages over GPT-4o. Furthermore, we validate the effectiveness of our model across 9 public benchmarks covering various common video understanding tasks, providing valuable insights for future Video LLMs.

Shihui Yan, Ziqi Zhou, Yufei Song et al.

Physical adversarial patch attacks critically threaten pedestrian detection, causing surveillance and autonomous driving systems to miss pedestrians and creating severe safety risks. Despite their effectiveness in controlled settings, existing physical attacks face two major limitations in practice: they lack systematic disruption of the multi-stage decision pipeline, enabling residual modules to offset perturbations, and they fail to model complex physical variations, leading to poor robustness. To overcome these limitations, we propose a novel pedestrian adversarial patch generation method that combines multi-stage collaborative attacks with robustness enhancement under physical diversity, called TriPatch. Specifically, we design a triplet loss consisting of detection confidence suppression, bounding-box offset amplification, and non-maximum suppression (NMS) disruption, which jointly act across different stages of the detection pipeline. In addition, we introduce an appearance consistency loss to constrain the color distribution of the patch, thereby improving its adaptability under diverse imaging conditions, and incorporate data augmentation to further enhance robustness against complex physical perturbations. Extensive experiments demonstrate that TriPatch achieves a higher attack success rate across multiple detector models compared to existing approaches.

Minghui Li, Yuanhang Wang, Peijin Guo et al.

Accurate prediction of Drug-Target Affinity (DTA) is crucial for reducing experimental costs and accelerating early screening in computational drug discovery. While sequence-based deep learning methods avoid reliance on costly 3D structures, they still overlook simultaneous modeling of global sequence semantic features and local topological structural features within drugs and proteins, and represent drugs as flat sequences without atomic-level, substructural-level, and molecular-level multi-scale features. We propose HiF-DTA, a hierarchical network that adopts a dual-pathway strategy to extract both global sequence semantic and local topological features from drug and protein sequences, and models drugs multi-scale to learn atomic, substructural, and molecular representations fused via a multi-scale bilinear attention module. Experiments on Davis, KIBA, and Metz datasets show HiF-DTA outperforms state-of-the-art baselines, with ablations confirming the importance of global-local extraction and multi-scale fusion.

Peijin Guo, Minghui Li, Hewen Pan et al.

While deep learning models play a crucial role in predicting antibody-antigen interactions (AAI), the scarcity of publicly available sequence-structure pairings constrains their generalization. Current AAI methods often focus on residue-level static details, overlooking fine-grained structural representations of antibodies and their inter-antibody similarities. To tackle this challenge, we introduce a multi-modality representation approach that integates 3D structural and 1D sequence data to unravel intricate intra-antibody hierarchical relationships. By harnessing these representations, we present MuLAAIP, an AAI prediction framework that utilizes graph attention networks to illuminate graph-level structural features and normalized adaptive graph convolution networks to capture inter-antibody sequence associations. Furthermore, we have curated an AAI benchmark dataset comprising both structural and sequence information along with interaction labels. Through extensive experiments on this benchmark, our results demonstrate that MuLAAIP outperforms current state-of-the-art methods in terms of predictive performance. The implementation code and dataset are publicly available at https://github.com/trashTian/MuLAAIP for reproducibility.

Junyu Shi, Minghui Li, Junguo Zuo et al.

Deepfakes, leveraging advanced AIGC (Artificial Intelligence-Generated Content) techniques, create hyper-realistic synthetic images and videos of human faces, posing a significant threat to the authenticity of social media. While this real-world threat is increasingly prevalent, existing academic evaluations and benchmarks for detecting deepfake forgery often fall short to achieve effective application for their lack of specificity, limited deepfake diversity, restricted manipulation techniques.To address these limitations, we introduce RedFace (Real-world-oriented Deepfake Face), a specialized facial deepfake dataset, comprising over 60,000 forged images and 1,000 manipulated videos derived from authentic facial features, to bridge the gap between academic evaluations and real-world necessity. Unlike prior benchmarks, which typically rely on academic methods to generate deepfakes, RedFace utilizes 9 commercial online platforms to integrate the latest deepfake technologies found "in the wild", effectively simulating real-world black-box scenarios.Moreover, RedFace's deepfakes are synthesized using bespoke algorithms, allowing it to capture diverse and evolving methods used by real-world deepfake creators. Extensive experimental results on RedFace (including cross-domain, intra-domain, and real-world social network dissemination simulations) verify the limited practicality of existing deepfake detection schemes against real-world applications. We further perform a detailed analysis of the RedFace dataset, elucidating the reason of its impact on detection performance compared to conventional datasets. Our dataset is available at: https://github.com/kikyou-220/RedFace.

Ziqi Zhou, Minghui Li, Wei Liu et al.

With the evolution of self-supervised learning, the pre-training paradigm has emerged as a predominant solution within the deep learning landscape. Model providers furnish pre-trained encoders designed to function as versatile feature extractors, enabling downstream users to harness the benefits of expansive models with minimal effort through fine-tuning. Nevertheless, recent works have exposed a vulnerability in pre-trained encoders, highlighting their susceptibility to downstream-agnostic adversarial examples (DAEs) meticulously crafted by attackers. The lingering question pertains to the feasibility of fortifying the robustness of downstream models against DAEs, particularly in scenarios where the pre-trained encoders are publicly accessible to the attackers. In this paper, we initially delve into existing defensive mechanisms against adversarial examples within the pre-training paradigm. Our findings reveal that the failure of current defenses stems from the domain shift between pre-training data and downstream tasks, as well as the sensitivity of encoder parameters. In response to these challenges, we propose Genetic Evolution-Nurtured Adversarial Fine-tuning (Gen-AF), a two-stage adversarial fine-tuning approach aimed at enhancing the robustness of downstream models. Our extensive experiments, conducted across ten self-supervised training methods and six datasets, demonstrate that Gen-AF attains high testing accuracy and robust testing accuracy against state-of-the-art DAEs.

Xianlong Wang, Hewen Pan, Hangtao Zhang et al.

Robotic manipulation in the physical world is increasingly empowered by \textit{large language models} (LLMs) and \textit{vision-language models} (VLMs), leveraging their understanding and perception capabilities. Recently, various attacks against such robotic policies have been proposed, with backdoor attacks drawing considerable attention for their high stealth and strong persistence capabilities. However, existing backdoor efforts are limited to simulators and suffer from physical-world realization. To address this, we propose \textit{TrojanRobot}, a highly stealthy and broadly effective robotic backdoor attack in the physical world. Specifically, we introduce a module-poisoning approach by embedding a backdoor module into the modular robotic policy, enabling backdoor control over the policy's visual perception module thereby backdooring the entire robotic policy. Our vanilla implementation leverages a backdoor-finetuned VLM to serve as the backdoor module. To enhance its generalization in physical environments, we propose a prime implementation, leveraging the LVLM-as-a-backdoor paradigm and developing three types of prime attacks, \ie, \textit{permutation}, \textit{stagnation}, and \textit{intentional} attacks, thus achieving finer-grained backdoors. Extensive experiments on the UR3e manipulator with 18 task instructions using robotic policies based on four VLMs demonstrate the broad effectiveness and physical-world stealth of TrojanRobot. Our attack's video demonstrations are available via a github link https://trojanrobot.github.io.

Yichen Wang, Yuxuan Chou, Ziqi Zhou et al.

As deep neural networks (DNNs) are widely applied in the physical world, many researches are focusing on physical-world adversarial examples (PAEs), which introduce perturbations to inputs and cause the model's incorrect outputs. However, existing PAEs face two challenges: unsatisfactory attack performance (i.e., poor transferability and insufficient robustness to environment conditions), and difficulty in balancing attack effectiveness with stealthiness, where better attack effectiveness often makes PAEs more perceptible. In this paper, we explore a novel perturbation-based method to overcome the challenges. For the first challenge, we introduce a strategy Deceptive RF injection based on robust features (RFs) that are predictive, robust to perturbations, and consistent across different models. Specifically, it improves the transferability and robustness of PAEs by covering RFs of other classes onto the predictive features in clean images. For the second challenge, we introduce another strategy Adversarial Semantic Pattern Minimization, which removes most perturbations and retains only essential adversarial patterns in AEsBased on the two strategies, we design our method Robust Feature Coverage Attack (RFCoA), comprising Robust Feature Disentanglement and Adversarial Feature Fusion. In the first stage, we extract target class RFs in feature space. In the second stage, we use attention-based feature fusion to overlay these RFs onto predictive features of clean images and remove unnecessary perturbations. Experiments show our method's superior transferability, robustness, and stealthiness compared to existing state-of-the-art methods. Additionally, our method's effectiveness can extend to Large Vision-Language Models (LVLMs), indicating its potential applicability to more complex tasks.

Yufei Song, Ziqi Zhou, Minghui Li et al.

With the rapid advancement of deep learning, the model robustness has become a significant research hotspot, \ie, adversarial attacks on deep neural networks. Existing works primarily focus on image classification tasks, aiming to alter the model's predicted labels. Due to the output complexity and deeper network architectures, research on adversarial examples for segmentation models is still limited, particularly for universal adversarial perturbations. In this paper, we propose a novel universal adversarial attack method designed for segmentation models, which includes dual feature separation and low-frequency scattering modules. The two modules guide the training of adversarial examples in the pixel and frequency space, respectively. Experiments demonstrate that our method achieves high attack success rates surpassing the state-of-the-art methods, and exhibits strong transferability across different models.

Hangtao Zhang, Yichen Wang, Shihui Yan et al.

Object detection models are vulnerable to backdoor attacks, where attackers poison a small subset of training samples by embedding a predefined trigger to manipulate prediction. Detecting poisoned samples (i.e., those containing triggers) at test time can prevent backdoor activation. However, unlike image classification tasks, the unique characteristics of object detection -- particularly its output of numerous objects -- pose fresh challenges for backdoor detection. The complex attack effects (e.g., "ghost" object emergence or "vanishing" object) further render current defenses fundamentally inadequate. To this end, we design TRAnsformation Consistency Evaluation (TRACE), a brand-new method for detecting poisoned samples at test time in object detection. Our journey begins with two intriguing observations: (1) poisoned samples exhibit significantly more consistent detection results than clean ones across varied backgrounds. (2) clean samples show higher detection consistency when introduced to different focal information. Based on these phenomena, TRACE applies foreground and background transformations to each test sample, then assesses transformation consistency by calculating the variance in objects confidences. TRACE achieves black-box, universal backdoor detection, with extensive experiments showing a 30% improvement in AUROC over state-of-the-art defenses and resistance to adaptive attacks.

Wei Wan, Yuxuan Ning, Shengshan Hu et al.

\textit{Federated learning} (FL) and \textit{split learning} (SL) are prevailing distributed paradigms in recent years. They both enable shared global model training while keeping data localized on users' devices. The former excels in parallel execution capabilities, while the latter enjoys low dependence on edge computing resources and strong privacy protection. \textit{Split federated learning} (SFL) combines the strengths of both FL and SL, making it one of the most popular distributed architectures. Furthermore, a recent study has claimed that SFL exhibits robustness against poisoning attacks, with a fivefold improvement compared to FL in terms of robustness. In this paper, we present a novel poisoning attack known as MISA. It poisons both the top and bottom models, causing a \textbf{\underline{misa}}lignment in the global model, ultimately leading to a drastic accuracy collapse. This attack unveils the vulnerabilities in SFL, challenging the conventional belief that SFL is robust against poisoning attacks. Extensive experiments demonstrate that our proposed MISA poses a significant threat to the availability of SFL, underscoring the imperative for academia and industry to accord this matter due attention.

Zihui Zhu, Ziqi Zhou, Yichen Wang et al.

Deep learning drives major advances in autonomous driving (AD), where object detectors are central to perception. However, adversarial attacks pose significant threats to the reliability and safety of these systems, with physical adversarial patches representing a particularly potent form of attack. Physical adversarial patch attacks pose severe risks but are usually crafted for a single model, yielding poor transferability to unseen detectors. We propose AdvAD, a transfer-based physical attack against object detection in autonomous driving. Instead of targeting a specific detector, AdvAD optimizes adversarial patches over multiple detection models in a unified framework, encouraging the learned perturbations to capture shared vulnerabilities across architectures. The optimization process adaptively balances model contributions and enforces robustness to physical variations. It further employs data augmentation and geometric transformations to maintain patch effectiveness under diverse physical conditions. Experiments in both digital and real-world settings show that AdvAD consistently outperforms state-of-the-art (SOTA) attacks in performance and transferability.

Yufei Song, Ziqi Zhou, Qi Lu et al.

Segmentation models exhibit significant vulnerability to adversarial examples in white-box settings, but existing adversarial attack methods often show poor transferability across different segmentation models. While some researchers have explored transfer-based adversarial attack (i.e., transfer attack) methods for segmentation models, the complex contextual dependencies within these models and the feature distribution gaps between surrogate and target models result in unsatisfactory transfer success rates. To address these issues, we propose SegTrans, a novel transfer attack framework that divides the input sample into multiple local regions and remaps their semantic information to generate diverse enhanced samples. These enhanced samples replace the original ones for perturbation optimization, thereby improving the transferability of adversarial examples across different segmentation models. Unlike existing methods, SegTrans only retains local semantic information from the original input, rather than using global semantic information to optimize perturbations. Extensive experiments on two benchmark datasets, PASCAL VOC and Cityscapes, four different segmentation models, and three backbone networks show that SegTrans significantly improves adversarial transfer success rates without introducing additional computational overhead. Compared to the current state-of-the-art methods, SegTrans achieves an average increase of 8.55% in transfer attack success rate and improves computational efficiency by more than 100%.

Ziqi Zhou, Menghao Deng, Yufei Song et al.

Benefiting from its superior feature learning capabilities and efficiency, deep hashing has achieved remarkable success in large-scale image retrieval. Recent studies have demonstrated the vulnerability of deep hashing models to backdoor attacks. Although these studies have shown promising attack results, they rely on access to the training dataset to implant the backdoor. In the real world, obtaining such data (e.g., identity information) is often prohibited due to privacy protection and intellectual property concerns. Embedding backdoors into deep hashing models without access to the training data, while maintaining retrieval accuracy for the original task, presents a novel and challenging problem. In this paper, we propose DarkHash, the first data-free backdoor attack against deep hashing. Specifically, we design a novel shadow backdoor attack framework with dual-semantic guidance. It embeds backdoor functionality and maintains original retrieval accuracy by fine-tuning only specific layers of the victim model using a surrogate dataset. We consider leveraging the relationship between individual samples and their neighbors to enhance backdoor attacks during training. By designing a topological alignment loss, we optimize both individual and neighboring poisoned samples toward the target sample, further enhancing the attack capability. Experimental results on four image datasets, five model architectures, and two hashing methods demonstrate the high effectiveness of DarkHash, outperforming existing state-of-the-art backdoor attack methods. Defense experiments show that DarkHash can withstand existing mainstream backdoor defense methods.

Yechao Zhang, Yingzhe Xu, Junyu Shi et al.

Deep neural networks (DNNs) are susceptible to universal adversarial perturbations (UAPs). These perturbations are meticulously designed to fool the target model universally across all sample classes. Unlike instance-specific adversarial examples (AEs), generating UAPs is more complex because they must be generalized across a wide range of data samples and models. Our research reveals that existing universal attack methods, which optimize UAPs using DNNs with static model parameter snapshots, do not fully leverage the potential of DNNs to generate more effective UAPs. Rather than optimizing UAPs against static DNN models with a fixed training set, we suggest using dynamic model-data pairs to generate UAPs. In particular, we introduce a dynamic maximin optimization strategy, aiming to optimize the UAP across a variety of optimal model-data pairs. We term this approach DM-UAP. DM-UAP utilizes an iterative max-min-min optimization framework that refines the model-data pairs, coupled with a curriculum UAP learning algorithm to examine the combined space of model parameters and data thoroughly. Comprehensive experiments on the ImageNet dataset demonstrate that the proposed DM-UAP markedly enhances both cross-sample universality and cross-model transferability of UAPs. Using only 500 samples for UAP generation, DM-UAP outperforms the state-of-the-art approach with an average increase in fooling ratio of 12.108%.

Minghui Li, Zikang Guo, Yang Wu et al.

Drug-target interaction is fundamental in understanding how drugs affect biological systems, and accurately predicting drug-target affinity (DTA) is vital for drug discovery. Recently, deep learning methods have emerged as a significant approach for estimating the binding strength between drugs and target proteins. However, existing methods simply utilize the drug's local information from molecular topology rather than global information. Additionally, the features of drugs and proteins are usually fused with a simple concatenation operation, limiting their effectiveness. To address these challenges, we proposed ViDTA, an enhanced DTA prediction framework. We introduce virtual nodes into the Graph Neural Network (GNN)-based drug feature extraction network, which acts as a global memory to exchange messages more efficiently. By incorporating virtual graph nodes, we seamlessly integrate local and global features of drug molecular structures, expanding the GNN's receptive field. Additionally, we propose an attention-based linear feature fusion network for better capturing the interaction information between drugs and proteins. Experimental results evaluated on various benchmarks including Davis, Metz, and KIBA demonstrate that our proposed ViDTA outperforms the state-of-the-art baselines.

Yechao Zhang, Yuxuan Zhou, Tianyu Li et al.

Transfer learning from pre-trained encoders has become essential in modern machine learning, enabling efficient model adaptation across diverse tasks. However, this combination of pre-training and downstream adaptation creates an expanded attack surface, exposing models to sophisticated backdoor embeddings at both the encoder and dataset levels--an area often overlooked in prior research. Additionally, the limited computational resources typically available to users of pre-trained encoders constrain the effectiveness of generic backdoor defenses compared to end-to-end training from scratch. In this work, we investigate how to mitigate potential backdoor risks in resource-constrained transfer learning scenarios. Specifically, we conduct an exhaustive analysis of existing defense strategies, revealing that many follow a reactive workflow based on assumptions that do not scale to unknown threats, novel attack types, or different training paradigms. In response, we introduce a proactive mindset focused on identifying clean elements and propose the Trusted Core (T-Core) Bootstrapping framework, which emphasizes the importance of pinpointing trustworthy data and neurons to enhance model security. Our empirical evaluations demonstrate the effectiveness and superiority of T-Core, specifically assessing 5 encoder poisoning attacks, 7 dataset poisoning attacks, and 14 baseline defenses across five benchmark datasets, addressing four scenarios of 3 potential backdoor threats.

Yichen Wang, Hangtao Zhang, Hewen Pan et al.

Vision-Language Models (VLMs), with their strong reasoning and planning capabilities, are widely used in embodied decision-making (EDM) tasks in embodied agents, such as autonomous driving and robotic manipulation. Recent research has increasingly explored adversarial attacks on VLMs to reveal their vulnerabilities. However, these attacks either rely on overly strong assumptions, requiring full knowledge of the victim VLM, which is impractical for attacking VLM-based agents, or exhibit limited effectiveness. The latter stems from disrupting most semantic information in the image, which leads to a misalignment between the perception and the task context defined by system prompts. This inconsistency interrupts the VLM's reasoning process, resulting in invalid outputs that fail to affect interactions in the physical world. To this end, we propose a fine-grained adversarial attack framework, ADVEDM, which modifies the VLM's perception of only a few key objects while preserving the semantics of the remaining regions. This attack effectively reduces conflicts with the task context, making VLMs output valid but incorrect decisions and affecting the actions of agents, thus posing a more substantial safety threat in the physical world. We design two variants of based on this framework, ADVEDM-R and ADVEDM-A, which respectively remove the semantics of a specific object from the image and add the semantics of a new object into the image. The experimental results in both general scenarios and EDM tasks demonstrate fine-grained control and excellent attack performance.

Peijin Guo, Minghui Li, Hewen Pan et al.

Accurate prediction of molecular metabolic stability (MS) is critical for drug research and development but remains challenging due to the complex interplay of molecular interactions. Despite recent advances in graph neural networks (GNNs) for MS prediction, current approaches face two critical limitations: (1) incomplete molecular modeling due to atom-centric message-passing mechanisms that disregard bond-level topological features, and (2) prediction frameworks that lack reliable uncertainty quantification. To address these challenges, we propose TrustworthyMS, a novel contrastive learning framework designed for uncertainty-aware metabolic stability prediction. First, a molecular graph topology remapping mechanism synchronizes atom-bond interactions through edge-induced feature propagation, capturing both localized electronic effects and global conformational constraints. Second, contrastive topology-bond alignment enforces consistency between molecular topology views and bond patterns via feature alignment, enhancing representation robustness. Third, uncertainty modeling through Beta-Binomial uncertainty quantification enables simultaneous prediction and confidence calibration under epistemic uncertainty. Through extensive experiments, our results demonstrate that TrustworthyMS outperforms current state-of-the-art methods in terms of predictive performance.

Minghui Li, Hao Zhang, Yechao Zhang et al.

Direct Prompt Injection (DPI) attacks pose a critical security threat to Large Language Models (LLMs) due to their low barrier of execution and high potential damage. To address the impracticality of existing white-box/gray-box methods and the poor transferability of black-box methods, we propose an activations-guided prompt injection attack framework. We first construct an Energy-based Model (EBM) using activations from a surrogate model to evaluate the quality of adversarial prompts. Guided by the trained EBM, we employ the token-level Markov Chain Monte Carlo (MCMC) sampling to adaptively optimize adversarial prompts, thereby enabling gradient-free black-box attacks. Experimental results demonstrate our superior cross-model transferability, achieving 49.6% attack success rate (ASR) across five mainstream LLMs and 34.6% improvement over human-crafted prompts, and maintaining 36.6% ASR on unseen task scenarios. Interpretability analysis reveals a correlation between activations and attack effectiveness, highlighting the critical role of semantic patterns in transferable vulnerability exploitation.

Lulu Xue, Shengshan Hu, Wei Lu et al.

With growing demands for privacy protection, security, and legal compliance (e.g., GDPR), machine unlearning has emerged as a critical technique for ensuring the controllability and regulatory alignment of machine learning models. However, a fundamental challenge in this field lies in effectively verifying whether unlearning operations have been successfully and thoroughly executed. Despite a growing body of work on unlearning techniques, verification methodologies remain comparatively underexplored and often fragmented. Existing approaches lack a unified taxonomy and a systematic framework for evaluation. To bridge this gap, this paper presents the first structured survey of machine unlearning verification methods. We propose a taxonomy that organizes current techniques into two principal categories -- behavioral verification and parametric verification -- based on the type of evidence used to assess unlearning fidelity. We examine representative methods within each category, analyze their underlying assumptions, strengths, and limitations, and identify potential vulnerabilities in practical deployment. In closing, we articulate a set of open problems in current verification research, aiming to provide a foundation for developing more robust, efficient, and theoretically grounded unlearning verification mechanisms.

Jiageng Wu, Xian Wu, Zhaopeng Qiu et al.

$\textbf{Objectives}$: Large Language Models (LLMs) such as ChatGPT and Med-PaLM have excelled in various medical question-answering tasks. However, these English-centric models encounter challenges in non-English clinical settings, primarily due to limited clinical knowledge in respective languages, a consequence of imbalanced training corpora. We systematically evaluate LLMs in the Chinese medical context and develop a novel in-context learning framework to enhance their performance. $\textbf{Materials and Methods}$: The latest China National Medical Licensing Examination (CNMLE-2022) served as the benchmark. We collected 53 medical books and 381,149 medical questions to construct the medical knowledge base and question bank. The proposed Knowledge and Few-shot Enhancement In-context Learning (KFE) framework leverages the in-context learning ability of LLMs to integrate diverse external clinical knowledge sources. We evaluated KFE with ChatGPT(GPT3.5), GPT4, Baichuan2(BC2)-7B, and BC2-13B in CNMLE-2022 and investigated the effectiveness of different pathways for incorporating LLMs with medical knowledge from 7 perspectives. $\textbf{Results}$: Directly applying ChatGPT failed to qualify for the CNMLE-2022 at a score of 51. Cooperated with the KFE, the LLMs with varying sizes yielded consistent and significant improvements. The ChatGPT's performance surged to 70.04 and GPT-4 achieved the highest score of 82.59. This surpasses the qualification threshold (60) and exceeds the average human score of 68.70. It also enabled a smaller BC2-13B to pass the examination, showcasing the great potential in low-resource settings. $\textbf{Conclusion}$: By synergizing medical knowledge through in-context learning, LLM can extend clinical insight beyond language barriers, significantly reducing language-related disparities of LLM applications and ensuring global benefit in healthcare.

Minghui Li, Sherman S. M. Chow, Shengshan Hu et al.

Convolutional neural network is a machine-learning model widely applied in various prediction tasks, such as computer vision and medical image analysis. Their great predictive power requires extensive computation, which encourages model owners to host the prediction service in a cloud platform. Recent researches focus on the privacy of the query and results, but they do not provide model privacy against the model-hosting server and may leak partial information about the results. Some of them further require frequent interactions with the querier or heavy computation overheads, which discourages querier from using the prediction service. This paper proposes a new scheme for privacy-preserving neural network prediction in the outsourced setting, i.e., the server cannot learn the query, (intermediate) results, and the model. Similar to SecureML (S&P'17), a representative work that provides model privacy, we leverage two non-colluding servers with secret sharing and triplet generation to minimize the usage of heavyweight cryptography. Further, we adopt asynchronous computation to improve the throughput, and design garbled circuits for the non-polynomial activation function to keep the same accuracy as the underlying network (instead of approximating it). Our experiments on MNIST dataset show that our scheme achieves an average of 122x, 14.63x, and 36.69x reduction in latency compared to SecureML, MiniONN (CCS'17), and EzPC (EuroS&P'19), respectively. For the communication costs, our scheme outperforms SecureML by 1.09x, MiniONN by 36.69x, and EzPC by 31.32x on average. On the CIFAR dataset, our scheme achieves a lower latency by a factor of 7.14x and 3.48x compared to MiniONN and EzPC, respectively. Our scheme also provides 13.88x and 77.46x lower communication costs than MiniONN and EzPC on the CIFAR dataset.

Shengshan Hu, Chengjun Cai, Qian Wang et al.

Searchable symmetric encryption (SSE) allows the data owner to outsource an encrypted database to a remote server in a private manner while maintaining the ability for selectively search. So far, most existing solutions focus on an honest-but-curious server, while security designs against a malicious server have not drawn enough attention. A few recent works have attempted to construct verifiable SSE that enables the data owner to verify the integrity of search results. Nevertheless, these verification mechanisms are highly dependent on specific SSE schemes, and fail to support complex queries. A general verification mechanism is desired that can be applied to all SSE schemes. In this work, instead of concentrating on a central server, we explore the potential of the smart contract, an emerging blockchain-based decentralized technology, and construct decentralized SSE schemes where the data owner can receive correct search results with assurance without worrying about potential wrongdoings of a malicious server. We study both public and private blockchain environments and propose two designs with a trade-off between security and efficiency. To better support practical applications, the multi-user setting of SSE is further investigated where the data owner allows authenticated users to search keywords in shared documents. We implement prototypes of our two designs and present experiments and evaluations to demonstrate the practicability of our decentralized SSE schemes.

Bo Han, Bo He, Rui Nian et al.

Extreme learning machine (ELM) as a neural network algorithm has shown its good performance, such as fast speed, simple structure etc, but also, weak robustness is an unavoidable defect in original ELM for blended data. We present a new machine learning framework called LARSEN-ELM for overcoming this problem. In our paper, we would like to show two key steps in LARSEN-ELM. In the first step, preprocessing, we select the input variables highly related to the output using least angle regression (LARS). In the second step, training, we employ Genetic Algorithm (GA) based selective ensemble and original ELM. In the experiments, we apply a sum of two sines and four datasets from UCI repository to verify the robustness of our approach. The experimental results show that compared with original ELM and other methods such as OP-ELM, GASEN-ELM and LSBoost, LARSEN-ELM significantly improve robustness performance while keeping a relatively high speed.