Mohammad Malekzadeh

LG
h-index7
13papers
606citations
Novelty54%
AI Score54

13 Papers

9.4LGDec 1, 2025Code
CLEF: Clinically-Guided Contrastive Learning for Electrocardiogram Foundation Models

Yuxuan Shu, Peter H. Charlton, Fahim Kawsar et al.

The electrocardiogram (ECG) is a key diagnostic tool in cardiovascular health. Single-lead ECG recording is integrated into both clinical-grade and consumer wearables. While self-supervised pretraining of foundation models on unlabeled ECGs improves diagnostic performance, existing approaches do not incorporate domain knowledge from clinical metadata. We introduce a novel contrastive learning approach that utilizes an established clinical risk score to adaptively weight negative pairs: clinically-guided contrastive learning. It aligns the similarities of ECG embeddings with clinically meaningful differences between subjects, with an explicit mechanism to handle missing metadata. On 12-lead ECGs from 161K patients in the MIMIC-IV dataset, we pretrain single-lead ECG foundation models at three scales, collectively called CLEF, using only routinely collected metadata without requiring per-sample ECG annotations. We evaluate CLEF on 18 clinical classification and regression tasks across 7 held-out datasets, and benchmark against 5 foundation model baselines and 3 self-supervised algorithms. When pretrained on 12-lead ECG data and tested on lead-I data, CLEF outperforms self-supervised foundation model baselines: the medium-sized CLEF achieves average AUROC improvements of at least 2.6% in classification and average reductions in MAEs of at least 3.2% in regression. Comparing with existing self-supervised learning algorithms, CLEF improves the average AUROC by at least 1.8%. Moreover, when pretrained only on lead-I data for classification tasks, CLEF performs comparably to the state-of-the-art ECGFounder, which was trained in a supervised manner. Overall, CLEF enables more accurate and scalable single-lead ECG analysis, advancing remote health monitoring. Code and pretrained CLEF models are available at: github.com/Nokia-Bell-Labs/ecg-foundation-model.

15.0LGNov 22, 2024Code
PRIMUS: Pretraining IMU Encoders with Multimodal Self-Supervision

Arnav M. Das, Chi Ian Tang, Fahim Kawsar et al.

Sensing human motions through Inertial Measurement Units (IMUs) embedded in personal devices has enabled significant applications in health and wellness. Labeled IMU data is scarce, however, unlabeled or weakly labeled IMU data can be used to model human motions. For video or text modalities, the "pretrain and adapt" approach utilizes large volumes of unlabeled or weakly labeled data to build a strong feature extractor, followed by adaptation to specific tasks using limited labeled data. However, pretraining methods are poorly understood for IMU data, and pipelines are rarely evaluated on out-of-domain tasks. We propose PRIMUS: a method for PRetraining IMU encoderS that uses a novel pretraining objective that is empirically validated based on downstream performance on both in-domain and out-of-domain datasets. The PRIMUS objective effectively enhances downstream performance by combining self-supervision, multimodal, and nearest-neighbor supervision. With fewer than 500 labeled samples per class, PRIMUS improves test accuracy by up to 15%, compared to state-of-the-art baselines. To benefit the broader community, we have open-sourced our code at github.com/nokia-bell-labs/pretrained-imu-encoders.

14.6LGJan 27, 2021Code
Dopamine: Differentially Private Federated Learning on Medical Data

Mohammad Malekzadeh, Burak Hasircioglu, Nitish Mital et al.

While rich medical datasets are hosted in hospitals distributed across the world, concerns on patients' privacy is a barrier against using such data to train deep neural networks (DNNs) for medical diagnostics. We propose Dopamine, a system to train DNNs on distributed datasets, which employs federated learning (FL) with differentially-private stochastic gradient descent (DPSGD), and, in combination with secure aggregation, can establish a better trade-off between differential privacy (DP) guarantee and DNN's accuracy than other approaches. Results on a diabetic retinopathy~(DR) task show that Dopamine provides a DP guarantee close to the centralized training counterpart, while achieving a better classification accuracy than FL with parallel DP where DPSGD is applied without coordination. Code is available at https://github.com/ipc-lab/private-ml-for-health.

29.3LGOct 27, 2024Code
PaPaGei: Open Foundation Models for Optical Physiological Signals

Arvind Pillai, Dimitris Spathis, Fahim Kawsar et al. · cambridge

Photoplethysmography (PPG) is the leading non-invasive technique for monitoring biosignals and cardiovascular health, with widespread adoption in both clinical settings and consumer wearable devices. While machine learning models trained on PPG signals have shown promise, they tend to be task-specific and struggle with generalization. Current research is limited by the use of single-device datasets, insufficient exploration of out-of-domain generalization, and a lack of publicly available models, which hampers reproducibility. To address these limitations, we present PaPaGei, the first open foundation model for PPG signals. The model is pre-trained on over 57,000 hours of data, comprising 20 million unlabeled PPG segments from publicly available datasets. We introduce a novel representation learning approach that leverages domain knowledge of PPG signal morphology across individuals, enabling the capture of richer representations compared to traditional contrastive learning methods. We evaluate PaPaGei against state-of-the-art time-series foundation models and self-supervised learning benchmarks across 20 tasks from 10 diverse datasets, spanning cardiovascular health, sleep disorders, pregnancy monitoring, and wellbeing assessment. Our model demonstrates superior performance, improving classification and regression metrics by 6.3% and 2.9% respectively in at least 14 tasks. Notably, PaPaGei achieves these results while being more data- and parameter-efficient, outperforming models that are 70x larger. Beyond accuracy, we examine model robustness across different skin tones, establishing a benchmark for bias evaluation in future models. PaPaGei can serve as both a feature extractor and an encoder for multimodal models, opening up new opportunities for multimodal health monitoring.

4.1LGOct 9, 2025
Contrastive Self-Supervised Learning at the Edge: An Energy Perspective

Fernanda Famá, Roberto Pereira, Charalampos Kalalas et al.

While contrastive learning (CL) shows considerable promise in self-supervised representation learning, its deployment on resource-constrained devices remains largely underexplored. The substantial computational demands required for training conventional CL frameworks pose a set of challenges, particularly in terms of energy consumption, data availability, and memory usage. We conduct an evaluation of four widely used CL frameworks: SimCLR, MoCo, SimSiam, and Barlow Twins. We focus on the practical feasibility of these CL frameworks for edge and fog deployment, and introduce a systematic benchmarking strategy that includes energy profiling and reduced training data conditions. Our findings reveal that SimCLR, contrary to its perceived computational cost, demonstrates the lowest energy consumption across various data regimes. Finally, we also extend our analysis by evaluating lightweight neural architectures when paired with CL frameworks. Our study aims to provide insights into the resource implications of deploying CL in edge/fog environments with limited processing capabilities and opens several research directions for its future optimization.

7.1LGOct 3, 2025
AdaBet: Gradient-free Layer Selection for Efficient Training of Deep Neural Networks

Irene Tenison, Soumyajit Chatterjee, Fahim Kawsar et al.

To utilize pre-trained neural networks on edge and mobile devices, we often require efficient adaptation to user-specific runtime data distributions while operating under limited compute and memory resources. On-device retraining with a target dataset can facilitate such adaptations; however, it remains impractical due to the increasing depth of modern neural nets, as well as the computational overhead associated with gradient-based optimization across all layers. Current approaches reduce training cost by selecting a subset of layers for retraining, however, they rely on labeled data, at least one full-model backpropagation, or server-side meta-training; limiting their suitability for constrained devices. We introduce AdaBet, a gradient-free layer selection approach to rank important layers by analyzing topological features of their activation spaces through Betti Numbers and using forward passes alone. AdaBet allows selecting layers with high learning capacity, which are important for retraining and adaptation, without requiring labels or gradients. Evaluating AdaBet on sixteen pairs of benchmark models and datasets, shows AdaBet achieves an average gain of 5% more classification accuracy over gradient-based baselines while reducing average peak memory consumption by 40%.

15.5LGMay 25, 2021Code
Honest-but-Curious Nets: Sensitive Attributes of Private Inputs Can Be Secretly Coded into the Classifiers' Outputs

Mohammad Malekzadeh, Anastasia Borovykh, Deniz Gündüz

It is known that deep neural networks, trained for the classification of non-sensitive target attributes, can reveal sensitive attributes of their input data through internal representations extracted by the classifier. We take a step forward and show that deep classifiers can be trained to secretly encode a sensitive attribute of their input data into the classifier's outputs for the target attribute, at inference time. Our proposed attack works even if users have a full white-box view of the classifier, can keep all internal representations hidden, and only release the classifier's estimations for the target attribute. We introduce an information-theoretical formulation for such attacks and present efficient empirical implementations for training honest-but-curious (HBC) classifiers: classifiers that can be accurate in predicting their target attribute, but can also exploit their outputs to secretly encode a sensitive attribute. Our work highlights a vulnerability that can be exploited by malicious machine learning service providers to attack their user's privacy in several seemingly safe scenarios; such as encrypted inferences, computations at the edge, or private knowledge distillation. Experimental results on several attributes in two face-image datasets show that a semi-trusted server can train classifiers that are not only perfectly honest but also accurately curious. We conclude by showing the difficulties in distinguishing between standard and HBC classifiers, discussing challenges in defending against this vulnerability of deep classifiers, and enumerating related open directions for future studies.

20.1CROct 17, 2020
Layer-wise Characterization of Latent Information Leakage in Federated Learning

Fan Mo, Anastasia Borovykh, Mohammad Malekzadeh et al.

Training deep neural networks via federated learning allows clients to share, instead of the original data, only the model trained on their data. Prior work has demonstrated that in practice a client's private information, unrelated to the main learning task, can be discovered from the model's gradients, which compromises the promised privacy protection. However, there is still no formal approach for quantifying the leakage of private information via the shared updated model or gradients. In this work, we analyze property inference attacks and define two metrics based on (i) an adaptation of the empirical $\mathcal{V}$-information, and (ii) a sensitivity analysis using Jacobian matrices allowing us to measure changes in the gradients with respect to latent information. We show the applicability of our proposed metrics in localizing private latent information in a layer-wise manner and in two settings where (i) we have or (ii) we do not have knowledge of the attackers' capabilities. We evaluate the proposed metrics for quantifying information leakage on three real-world datasets using three benchmark models.

6.6DCSep 4, 2020
Running Neural Networks on the NIC

Giuseppe Siracusano, Salvator Galea, Davide Sanvito et al.

In this paper we show that the data plane of commodity programmable (Network Interface Cards) NICs can run neural network inference tasks required by packet monitoring applications, with low overhead. This is particularly important as the data transfer costs to the host system and dedicated machine learning accelerators, e.g., GPUs, can be more expensive than the processing task itself. We design and implement our system -- N3IC -- on two different NICs and we show that it can greatly benefit three different network monitoring use cases that require machine learning inference as first-class-primitive. N3IC can perform inference for millions of network flows per second, while forwarding traffic at 40Gb/s. Compared to an equivalent solution implemented on a general purpose CPU, N3IC can provide 100x lower processing latency, with 1.5x increase in throughput.

10.3LGNov 14, 2019Code
Privacy and Utility Preserving Sensor-Data Transformations

Mohammad Malekzadeh, Richard G. Clegg, Andrea Cavallaro et al.

Sensitive inferences and user re-identification are major threats to privacy when raw sensor data from wearable or portable devices are shared with cloud-assisted applications. To mitigate these threats, we propose mechanisms to transform sensor data before sharing them with applications running on users' devices. These transformations aim at eliminating patterns that can be used for user re-identification or for inferring potentially sensitive activities, while introducing a minor utility loss for the target application (or task). We show that, on gesture and activity recognition tasks, we can prevent inference of potentially sensitive activities while keeping the reduction in recognition accuracy of non-sensitive activities to less than 5 percentage points. We also show that we can reduce the accuracy of user re-identification and of the potential inference of gender to the level of a random guess, while keeping the accuracy of activity recognition comparable to that obtained on the original data.

10.7LGSep 10, 2019Code
Privacy-Preserving Bandits

Mohammad Malekzadeh, Dimitrios Athanasakis, Hamed Haddadi et al.

Contextual bandit algorithms~(CBAs) often rely on personal data to provide recommendations. Centralized CBA agents utilize potentially sensitive data from recent interactions to provide personalization to end-users. Keeping the sensitive data locally, by running a local agent on the user's device, protects the user's privacy, however, the agent requires longer to produce useful recommendations, as it does not leverage feedback from other users. This paper proposes a technique we call Privacy-Preserving Bandits (P2B); a system that updates local agents by collecting feedback from other local agents in a differentially-private manner. Comparisons of our proposed approach with a non-private, as well as a fully-private (local) system, show competitive performance on both synthetic benchmarks and real-world data. Specifically, we observed only a decrease of 2.6% and 3.6% in multi-label classification accuracy, and a CTR increase of 0.0025 in online advertising for a privacy budget $ε\approx 0.693$. These results suggest P2B is an effective approach to challenges arising in on-device privacy-preserving personalization.

2.2MLJun 21, 2019Code
Modeling and Forecasting Art Movements with CGANs

Edoardo Lisi, Mohammad Malekzadeh, Hamed Haddadi et al.

Conditional Generative Adversarial Networks~(CGAN) are a recent and popular method for generating samples from a probability distribution conditioned on latent information. The latent information often comes in the form of a discrete label from a small set. We propose a novel method for training CGANs which allows us to condition on a sequence of continuous latent distributions $f^{(1)}, \ldots, f^{(K)}$. This training allows CGANs to generate samples from a sequence of distributions. We apply our method to paintings from a sequence of artistic movements, where each movement is considered to be its own distribution. Exploiting the temporal aspect of the data, a vector autoregressive (VAR) model is fitted to the means of the latent distributions that we learn, and used for one-step-ahead forecasting, to predict the latent distribution of a future art movement $f^{(K+1)}$. Realisations from this distribution can be used by the CGAN to generate "future" paintings. In experiments, this novel methodology generates accurate predictions of the evolution of art. The training set consists of a large dataset of past paintings. While there is no agreement on exactly what current art period we find ourselves in, we test on plausible candidate sets of present art, and show that the mean distance to our predictions is small.

20.3LGOct 26, 2018Code
Mobile Sensor Data Anonymization

Mohammad Malekzadeh, Richard G. Clegg, Andrea Cavallaro et al.

Motion sensors such as accelerometers and gyroscopes measure the instant acceleration and rotation of a device, in three dimensions. Raw data streams from motion sensors embedded in portable and wearable devices may reveal private information about users without their awareness. For example, motion data might disclose the weight or gender of a user, or enable their re-identification. To address this problem, we propose an on-device transformation of sensor data to be shared for specific applications, such as monitoring selected daily activities, without revealing information that enables user identification. We formulate the anonymization problem using an information-theoretic approach and propose a new multi-objective loss function for training deep autoencoders. This loss function helps minimizing user-identity information as well as data distortion to preserve the application-specific utility. The training process regulates the encoder to disregard user-identifiable patterns and tunes the decoder to shape the output independently of users in the training set. The trained autoencoder can be deployed on a mobile or wearable device to anonymize sensor data even for users who are not included in the training dataset. Data from 24 users transformed by the proposed anonymizing autoencoder lead to a promising trade-off between utility and privacy, with an accuracy for activity recognition above 92% and an accuracy for user identification below 7%.