13.0CLMar 6, 2025
Benchmarking Large Language Models on Multiple Tasks in Bioinformatics NLP with PromptingJiyue Jiang, Pengan Chen, Jiuming Wang et al.
Large language models (LLMs) have become important tools in solving biological problems, offering improvements in accuracy and adaptability over conventional methods. Several benchmarks have been proposed to evaluate the performance of these LLMs. However, current benchmarks can hardly evaluate the performance of these models across diverse tasks effectively. In this paper, we introduce a comprehensive prompting-based benchmarking framework, termed Bio-benchmark, which includes 30 key bioinformatics tasks covering areas such as proteins, RNA, drugs, electronic health records, and traditional Chinese medicine. Using this benchmark, we evaluate six mainstream LLMs, including GPT-4o and Llama-3.1-70b, etc., using 0-shot and few-shot Chain-of-Thought (CoT) settings without fine-tuning to reveal their intrinsic capabilities. To improve the efficiency of our evaluations, we demonstrate BioFinder, a new tool for extracting answers from LLM responses, which increases extraction accuracy by round 30% compared to existing methods. Our benchmark results show the biological tasks suitable for current LLMs and identify specific areas requiring enhancement. Furthermore, we propose targeted prompt engineering strategies for optimizing LLM performance in these contexts. Based on these findings, we provide recommendations for the development of more robust LLMs tailored for various biological applications. This work offers a comprehensive evaluation framework and robust tools to support the application of LLMs in bioinformatics.
1.2CENov 12, 2024
EUR/USD Exchange Rate Forecasting incorporating Text Mining Based on Pre-trained Language Models and Deep Learning MethodsHongcheng Ding, Xiangyu Shi, Ruiting Deng et al.
This study introduces a novel approach for EUR/USD exchange rate forecasting that integrates deep learning, textual analysis, and particle swarm optimization (PSO). By incorporating online news and analysis texts as qualitative data, the proposed PSO-LSTM model demonstrates superior performance compared to traditional econometric and machine learning models. The research employs advanced text mining techniques, including sentiment analysis using the RoBERTa-Large model and topic modeling with LDA. Empirical findings underscore the significant advantage of incorporating textual data, with the PSO-LSTM model outperforming benchmark models such as SVM, SVR, ARIMA, and GARCH. Ablation experiments reveal the contribution of each textual data category to the overall forecasting performance. The study highlights the transformative potential of artificial intelligence in finance and paves the way for future research in real-time forecasting and the integration of alternative data sources.
AutoMC: Automated Model Compression based on Domain Knowledge and Progressive search strategyChunnan Wang, Hongzhi Wang, Xiangyu Shi
Model compression methods can reduce model complexity on the premise of maintaining acceptable performance, and thus promote the application of deep neural networks under resource constrained environments. Despite their great success, the selection of suitable compression methods and design of details of the compression scheme are difficult, requiring lots of domain knowledge as support, which is not friendly to non-expert users. To make more users easily access to the model compression scheme that best meet their needs, in this paper, we propose AutoMC, an effective automatic tool for model compression. AutoMC builds the domain knowledge on model compression to deeply understand the characteristics and advantages of each compression method under different settings. In addition, it presents a progressive search strategy to efficiently explore pareto optimal compression scheme according to the learned prior knowledge combined with the historical evaluation information. Extensive experimental results show that AutoMC can provide satisfying compression schemes within short time, demonstrating the effectiveness of AutoMC.